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Discovering an Antimalarial Drug in Mao’s China

Codon

However, the blandly clinical package of artemisinin and artesunate tablets reveals little about how the key compound was first discovered. Current vaccines and medicines work by intervening against these life phases. Multiple species of Plasmodium infect humans, but P. Nobody had an answer.

Drugs 140
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Codon Digest: Injected Gene Editors

Codon

Read Inhalable nanoparticles, packaged with mRNA or CRISPR systems, efficiently edit lung cells. They achieved high gene-editing efficiencies in airway epithelial cells (which are normally hard to target.) mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 Nature Biotechnology.

DNA 52
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Levers for Biological Progress

Codon

Such models will, in turn, make it much easier to invent the sorts of platform tools that Amodei asserts “drive >50% of progress in biology,” such as CRISPR and mRNA vaccines, because the creation of these tools ultimately derive from a deeper understanding of how cells work. Even the humble E.

DNA 128