SCIENMAG: Medicine & Health

JULY 13, 2023

RESEARCH REVEALS HOW COVID-19 VIRUS INFECTS THE PLACENTA, AND HOW THIS CAN BE PREVENTED Credit: Monash University RESEARCH REVEALS HOW COVID-19 VIRUS INFECTS THE PLACENTA, AND HOW THIS CAN BE PREVENTED In a landmark study published in Nature Cell Biology, Australian researchers, led by Professor Jose Polo from Monash University and the University of (..)

Cell Biology 77

Cell Biology Virus Research 77

Drug Target Review

NOVEMBER 17, 2023

About the authors Aleta Pupovac Publications Officer, Cartherics Aleta is a cell biologist and immunologist who is passionate about translational science. Alan is Emeritus Professor Monash University and Distinguished Scientist, Hudson Institute for Medical Research, Clayton, Victoria, Australia.

Therapies 118

Therapies Clinical Trials Cell Biology Trials 118

Drug Target Review

OCTOBER 16, 2023

They self-assemble and in doing so retain the genetics, structure and heterogeneity of cell types found in the tissue they derive from. Their close resemblance to the patient and disease state makes PDOs a valuable and scalable source of biological material to interrogate in disease research and drug discovery.

Disease 122

Disease Immune Response Cell Biology Therapies 122

Drug Target Review

MARCH 3, 2025

Turning this tide, Professor Jens Christian Schwamborn, a cell biology expert at the University of Luxembourg and co-founder of OrganoTherapeutics , is leading a groundbreaking effort to transform our understanding and treatment of these debilitating diseases. Schwamborns research focuses on creating patient-specific brain organoids.

Disease 52

Disease Treatment Therapies Cell Biology 52

Chemical Biology and Drug Design

JANUARY 5, 2024

After the corresponding transfection or treatment with inhibitor of catenin-responsive transcription-3 (iCRT-3), abovementioned CRC cell biological behaviors as well as expression levels of HOXB7 and β-catenin were evaluated. μM THA dwindled CRC cell viability, migration, and invasion, and facilitated apoptosis.

Bioinformatics 100

Bioinformatics Cell Biology Treatment Research 100

Drug Target Review

NOVEMBER 24, 2023

The National Institutes of Health (NIH) awarded new recipients of the Brain Research Through Advancing Innovative Neurotechnologies® Initiative (BRAIN Initiative) funding. Machine learning Operating biological imaging techniques invented by Lichtman and his colleagues, the researchers will carry out a two-tiered system for the NIH project.

Cell Biology 105

Cell Biology Engineering Research Treatment 105

Reprocell

NOVEMBER 20, 2023

CHIR99021, also known as CT99021, is a small molecule compound that has proven to be a potent and versatile tool in the world of stem cell biology and regenerative medicine. This activation facilitates the derivation of high-quality, undifferentiated cell populations.

Research 52

Research Small Molecule Cell Biology 52

Chemical Biology and Drug Design

JULY 27, 2023

DDP-resistant NPC cells were established by treatment with DDP at increased concentrations (2, 4, 6, 8, or 10 μg/mL). Cell biological behaviors were assessed via cell function experiments. MicroRNA-577 and EIF5A2 mRNA expressions were detected by qRT-PCR.

Cell Biology 100

Cell Biology Regulations Treatment Research 100

The Pharma Data

JUNE 28, 2021

24 scientists will receive both financial and scientific support for their crop science research proposal / Successful projects have the potential to become future collaborations with Bayer / Researchers selected from more than 600 proposals representing 39 countries. I was thrilled to have my project chosen!”

Research 52

Research Cell Biology Science Disease 52

Drug Target Review

NOVEMBER 1, 2023

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. He is a researcher at University of Oldenburg, Germany.

Clinical Trials 134

Clinical Trials Trials Small Molecule Disease 134

Drug Target Review

JUNE 5, 2023

Dr Paul Moore emphasises the significance of T cell -engaging bispecific antibodies, like ZW171, in treating solid cancer tumours by overcoming biological obstacles in the tumour microenvironment. No single therapeutic mode has cured all cancers, so diversification in research and treatment is warranted.

Treatment 100

Treatment Pharmacokinetics Drugs Cell Biology 100

The Pharma Data

DECEMBER 31, 2020

Researchers at Stanford Medicine found that COVID-19 antibodies preferentially target different parts of the SARS-CoV-2 virus in mild COVID-19 cases than they do in severe cases. Astrocytes are star-shaped cells that help structure the brain and maintain homeostasis with involvement in neuronal signaling.

Research 52

Research Virus Immune Response Cell Biology 52

Drug Target Review

APRIL 12, 2024

Controlling the amount of RNP entering each cell is challenging, leading to uncertainty about the ratio of RNP that reaches any specific cell. Importantly for the researcher, there is no assurance that the RNP, once inside the cells, will reliably enter their nuclei.

Cell Biology 105

Cell Biology FDA Approval FDA Research 105

Broad Institute

MARCH 25, 2024

Navarro later became the first in her family to attend a four-year college, earning her degree in microbiology from the University of Texas at El Paso, followed by a stint doing research at Novartis in Cambridge, MA, and then graduate studies at MIT to earn her Ph.D. in cell biology. Why do you think it works?,”

Science 111

Science Cell Biology Research DNA 111

Drug Target Review

APRIL 12, 2024

Controlling the amount of RNP entering each cell is challenging, leading to uncertainty about the ratio of RNP that reaches any specific cell. Importantly for the researcher, there is no assurance that the RNP, once inside the cells, will reliably enter their nuclei.

Cell Biology 98

Cell Biology FDA Approval FDA Research 98

Drug Target Review

JULY 23, 2024

Shortly after finishing my studies, I landed my first job in industry working on cell biology research for several disease indications. Mentors are essential for growth, especially as they provided a trusted resource to help navigate new research frontiers and obstacles.

Small Molecule 116

Small Molecule Targeted Protein Degradation Science Disease 116

Drug Target Review

OCTOBER 31, 2023

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

Cell Biology 107

Cell Biology Pharmaceuticals Science Disease 107

KIF1A

MAY 24, 2023

It’s an investment in the long-term success of rare disease research, even if it doesn’t provide an immediate clinical on-ramp. Rebecca Shi of Stanford University, who worked to create a research laboratory course for undergraduates in the Stanford Biology department for the Spring 2023 semester. What Can We Learn From A Worm?

Disease 98

Disease Laboratories Research Science 98

The Pharma Data

MARCH 16, 2022

The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cell biology. Protein labeling (e.g.

Cell Biology 52

Cell Biology Molecular Biology Science Laboratories 52

The Pharma Data

SEPTEMBER 21, 2020

Investors include SV Health Investors and Cancer Research UK. A biotech company spun out of the University of Edinburgh will utilise research to develop new gene therapies to target different types of cancer.

Therapies 52

Therapies Cell Biology Licensing Licensing 52

Codon

APRIL 9, 2024

Chinese researchers scoured ancient medical texts containing written records of malaria outbreaks and the plant-derived recipes that were used to treat them nearly two thousand years ago. Over the course of 12 years, the Walter Reed Army Institute of Research (WRAIR) screened more than 250,000 compounds in search of an efficacious treatment.

Drugs 139

Drugs Science Research Doctors 139

Drug Target Review

DECEMBER 21, 2023

A recently published study 1 from a large team of cell biologists sheds new light on cellular organisation and variability. Can you give a brief overview of your research methods? SR: This project started in the early days of the Allen Institute for Cell Science, nearly seven years ago.

International 105

International Science Disease Research 105

Drug Target Review

JANUARY 31, 2024

During my fellowship at Cleveland Clinic, the opportunity to interact with clinicians helped me see the journey of a medicinal entity from the start – through all its research stages to the end, where it had immense impact on patient lives. It was the first time I had experienced the power of having allies and mentors.

Clinical Trials 97

Clinical Trials Production Science Research 97

PerkinElmer

JANUARY 21, 2022

1 To address the urgent need for new therapies, the UK’s Medical Research Council (MRC), a national public agency supporting health science and research, established the Dementias Platform United Kingdom (DPUK) in 2014. We are intent on developing a one-stop-shop portal for global researchers,” Prof. 2022 [cited 6 January 2022].

Cell Biology 52

Cell Biology Disease Treatment Science 52

Broad Institute

FEBRUARY 29, 2024

Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram. Senior Research Scientist Michal Lipinski is a senior research scientist at the Spatial Technology Platform of the Broad Institute of MIT and Harvard, where he works under the supervision of Sami Farhi. Nat Methods. 2021;18(11):1352-1362.

Cell Biology 52

Cell Biology Disease Science Treatment 52

Drug Target Review

JUNE 7, 2024

She has deep knowledge in Immunology and T cell biology, and 13 years of experience in Research (seven of them in biotech at Immunocore), including pipeline programme leadership. Dr Ribeiro holds a PhD in Biomedical Sciences from University of Porto, Portugal, studying T cell and thymus development.

Engineering 81

Engineering Clinical Trials Therapies Cell Biology 81

The Pharma Data

FEBRUARY 24, 2022

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development. Their findings are published online in Nature Cell Biology.

Small Molecule 52

Small Molecule Cell Biology Research Drug Development 52

The Pharma Data

JUNE 26, 2021

Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection. All current COVID-19 vaccines and antibody-based therapeutics were designed to disrupt this route into cells, which requires a receptor called ACE2. The study is published June 23 in Cell Reports.

Virus 52

Virus Cell Biology Vaccine Research 52

Drug Target Review

AUGUST 10, 2023

A breakthrough study conducted by researchers at the Keck School of Medicine of USC has shown a remarkable finding: during moments of stress, cancer cells undergo a transformative process. A crucial protein within these cells migrates to the nucleus, effectively reprogramming them to exhibit increased mobility and invasiveness.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

Drug Target Review

JUNE 29, 2023

Could you share an example of a specific project or some research that you have worked on and the impact it has had in your field? How has your research in STEM contributed to advancements or improvements in your field, and what potential future applications or implications do you foresee based on your work?

Therapies 115

Therapies Science Production Cell Biology 115

Alta Sciences

JANUARY 31, 2025

It owned the societal name of the Canadian Association for Research on Drug Safety. The meeting reflected on daily exposures and the boundless toxicology research to investigate the consequences of exposures across dietary, inhalation, and environmental factors through a forensic lens. Tags Preclinical Research Weight 15

Cell Biology 52

Cell Biology Pharmaceutical Companies Clinical Research Government 52

The Pharma Data

OCTOBER 27, 2021

million expansion will bring high quality seeds to worldwide markets faster, providing solutions for growers and meeting consumer demands / The seven-hectare global Product Design Center in San Nicolás includes state-of-the-art lab space for cell biology research and greenhouses for seed production.

Cell Biology 40

Cell Biology Production Laboratories Marketing 40

The Pharma Data

MARCH 25, 2022

Researchers at Karolinska Institutet in Sweden have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants. The approach led to the discovery of multiple nanobodies that in cell cultures and mice effectively blocked infection with different SARS-CoV-2 variants.

Molecular Biology 52

Molecular Biology Laboratories Cell Biology Science 52

The Pharma Data

MARCH 15, 2022

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilising the protein and making it more potent.

Cell Biology 52

Cell Biology DNA Research Vaccine 52

Codon

OCTOBER 22, 2024

He suggests that peer review doesn’t “do the thing it’s supposed to do” — namely, “catch bad research and prevent it from being published,” so perhaps scientists would be better off uploading PDFs to the internet where review and oversight can happen post-publication. Some politicians, such as Rep.

Science 110

Science Research Government Cell Biology 110

Precision for Medicine

APRIL 7, 2023

This provides value to researchers executing clinical trials, particularly those developing novel therapeutics and vaccines, where sample processing requires geographical proximity to the trial site and samples need to be processed within hours of collecting them from patients.

Laboratories 52

Laboratories Clinical Research Clinical Trials Cell Biology 52

Drug Target Review

AUGUST 24, 2023

Prior to joining CatalYm, Christine co-founded Rigontec in 2014 where she led the company’s discovery and non-clinical development activities as Senior Vice President, Research. Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration. Current Opinion in Cell Biology.

Treatment 98

Treatment Therapies Clinical Development Cell Biology 98