Cell Biology RNA Science 
Broad Institute
OCTOBER 28, 2024
Scientists then annotate the cells with this information, a process that can take days or even weeks, depending on the number of cells being labeled, and requires labor-intensive literature and database searches. We wanted to build a tool like that for cell biology. Overall, how can AI help advance cell biology?
Broad Institute
OCTOBER 11, 2023
By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. Along the way, TIDE is showing how careful, systematic science at scale can quickly home in on promising drug targets.
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Drug Target Review
JULY 23, 2024
I sharpened my focus in my early teen age years when I decided I wanted to harness my interest in human biology to make medicines for people. I studied Natural Sciences at the University of Cambridge, where I was exposed to a range of disciplines from chemistry to physiology, specialising in my last year in biochemistry.
Codon
FEBRUARY 20, 2024
At any given moment, thousands of messenger RNAs are being translated into proteins by ribosomes, which are protein-making machines that are, themselves, made from a mixture of proteins and RNA. 3 Part of the beauty of science is that it builds upon itself, one experiment at a time. Hundreds of proteins do this at the same time.
Drug Target Review
AUGUST 10, 2023
This discovery sheds new light on the intricate mechanisms at play within cancer cells when faced with adverse conditions. When bound to GRP78, ID2 loses its inhibitory function, leading to increased invasiveness of cancer cells.
Codon
APRIL 9, 2023
“Computer science is to biology what calculus is to physics.” Small snippets of double-stranded RNA were sprayed onto hot pepper plants to control a pest, called Frankliniella occidentalis. The RNA strands shut down a specific gene in the insects, and killed half after 7 days. Nature Chemical Biology.
Codon
APRIL 2, 2023
Basic Science *No evidence for a common blood microbiome based on a population study of 9,770 healthy humans. Read A new DNA polymerase variant, called RT-KTq I614Y, can directly detect RNA modifications, including pseudouridine (Ψ) and queuosine (Q). Massively parallel profiling of RNA-targeting CRISPR-Cas13d.
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