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New machine learning-based single-cell search engine makes cell annotation faster, more efficient

Broad Institute

Scientists then annotate the cells with this information, a process that can take days or even weeks, depending on the number of cells being labeled, and requires labor-intensive literature and database searches. We wanted to build a tool like that for cell biology. Overall, how can AI help advance cell biology?

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Condensate biology: advancing drug discovery for complex diseases

Drug Target Review

The aim is to establish condensate biology as a fundamental branch of cell biology – “cell biology 2.0” The underlying biology and processes upon which the company was founded have broad applicability across various human disease areas. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98
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CAR-NK cells: promising for cancer therapy

Drug Target Review

About the authors Aleta Pupovac Publications Officer, Cartherics Aleta is a cell biologist and immunologist who is passionate about translational science. In 2019, she joined Cartherics focusing on the science underpinning induced pluripotential stem cell differentiation to natural killer cells, and how to manufacture them.

Therapies 118
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Patient-derived organoids in disease modelling

Drug Target Review

Nikki drives adoption of 3D cellular models of human disease by applying her expertise in cell biology to drug discovery and high-throughput screening. Nikki’s life sciences experience spans leadership, commercial and research roles. About the author Nikki Carter Commercial Organoid Innovation Director, Molecular Devices.

Disease 122
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#WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers

Broad Institute

By Leah Eisenstadt March 25, 2024 Credit: Allison Colorado, Broad Communications Alex Navarro, Senior Program Coordinator for the Broad Biomedical Post-baccalaureate Scholars Program Alex Navarro didn’t always aspire to a career in science. in cell biology. It was fun to spend so much time watching cells divide.

Science 111
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#ScienceSaturday: March 2, 2024

KIF1A

Read the Article Rare Roundup The Jackson Laboratory offers “Exploring Rare Disease Through Translational Research” MiniCourse Human health is incredibly complex; developing safe, effective treatments requires knowledge of molecular mechanisms, cell biology, and drug administration.

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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. Along the way, TIDE is showing how careful, systematic science at scale can quickly home in on promising drug targets.

Research 137