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New molecular insights on medical cannabis

Drug Target Review

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. The Journal of Cell Biology. 2002 Jul 22;158(2):227–33.

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AM-Pharma Appoints Chief Medical Officer and VP Manufacturing to Support Global Pivotal Trial in Sepsis-associated Acute Kidney Injury

The Pharma Data

We welcome them to our team and I am confident in our collective abilities to execute this large late-stage trial enrolling up to 1,600 patients with sepsis and acute kidney injury.”. At Aduro, he was responsible for all manufacturing and supply chain activities for the company’s biologics and small molecules and managed a transatlantic team.

Trials 40
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The future of mRNA biology and AI convergence

Drug Target Review

Where do you see the future of mRNA biology and AI converging, and how does Anima Biotech plan to lead this convergence? mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer.

Disease 105
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Codon Digest: Injected Gene Editors

Codon

Read Safety and pharmacokinetics of escalating doses of neutralising monoclonal antibody CAP256V2LS administered with and without VRC07-523LS in HIV-negative women in South Africa (CAPRISA 012B): a phase 1, dose-escalation, randomised controlled trial. An open-source FACS automation system for high-throughput cell biology.

DNA 52
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. Read Microbes in the wild ‘talk’ to their neighbors by emitting, and sensing, small chemicals. Cell Systems.

Vaccine 52
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. Read Microbes in the wild ‘talk’ to their neighbors by emitting, and sensing, small chemicals. Cell Systems.

Vaccine 52
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Obstacles and innovations of macrocyclic drug development

Drug Target Review

Traditionally, drug discovery has focused on small-molecule therapeutics, typically with a molecular weight of less than 500 Daltons. 2 Typically, small-molecule drugs target active sites buried inside proteins. Phase III trials for MK-0616 commenced in the second half of 2023.