Drug Target Review

OCTOBER 31, 2023

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

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Precision for Medicine

APRIL 7, 2023

This provides value to researchers executing clinical trials, particularly those developing novel therapeutics and vaccines, where sample processing requires geographical proximity to the trial site and samples need to be processed within hours of collecting them from patients.

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The Pharma Data

OCTOBER 22, 2020

Monalizumab, Innate’s lead partnered asset, is a potentially first-in-class immune checkpoint inhibitor targeting NKG2A receptors expressed on tumor infiltrating cytotoxic CD8+ T cells and NK cells. Dosing of the first patient in this trial has triggered a $50 million milestone payment from AstraZeneca to Innate. “W

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Drug Target Review

JUNE 29, 2023

Obviously there are lots of issues to work on, but it’s a real modality that is changing people’s lives for the long term and changing the way we think about cancer treatments. When it comes down to cell biology itself, cells can do so many different things.

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The Pharma Data

NOVEMBER 17, 2021

Now, new research led by investigators at Harvard Medical School and Boston Children’s Hospital points to a well-known and widely available drug called disulfiram as a possible treatment for COVID-19. The authors hope that the study will motivate large international phase 3 trials of the drug. ” Sander recalled.

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DrugBank

JUNE 27, 2023

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care.

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The Pharma Data

JANUARY 23, 2021

Assessing the morphological and architectural changes in collagen fibers with the platform could potentially aid TNBC clinical trials in categorizing patients and monitoring therapeutic responses. On a larger scale, the tool may greatly aid existing and future TNBC studies that are currently exploring new therapies for targeted treatments.

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The Pharma Data

DECEMBER 1, 2020

is a commercial stage oncology-focused biotech company dedicated to improving treatment and clinical outcomes for patients through therapeutic antibodies that harness the immune system to fight cancer. About Innate Pharma: Innate Pharma S.A.

Cell Biology 52

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Drug Target Review

DECEMBER 21, 2023

Where do you see the future of mRNA biology and AI converging, and how does Anima Biotech plan to lead this convergence? mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer.

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The Pharma Data

JANUARY 3, 2021

Both will help NexImmune advance current early-stage clinical trials and will guide Company’s translational efforts to develop new immunotherapy products. Both Jerry and Jeff have proven and successful track records in the design and execution of early and late-stage clinical trials that have evaluated novel immune therapies.

Immune Response 40

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Codon

APRIL 2, 2023

Mice and human cells that were given the therapy had normal levels of the survival motor neuron protein, and no symptoms. When delivered using AAV9 in mice, the treatment significantly improved motor function and extended average lifespan. An open-source FACS automation system for high-throughput cell biology. Wiener D.M.

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The Pharma Data

JANUARY 4, 2021

Such trifunctional NKCEs have proven more effective in pre-clinical models than classical antibodies directed against the same tumor target, as co-engagement of multiple surface receptors on NK cells is required for their full activation. About NKp46-based NKCE: NKp46 is an activating receptor expressed on all NK cells.

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The Pharma Data

MARCH 11, 2021

Second, the biorevolution is driving innovation in all of Bayer’s divisions – with major progress in cell biology, gene editing and data science. And third, the company is accelerating its transformation and further increasing efficiency.

Science 52

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Codon

OCTOBER 22, 2024

This is a strong indication that peer reviewers push back against the aforementioned signs of importance hacking — namely, inflated importance and a weak treatment of limitations. Interestingly, the study found that peer review most improved the author’s discussions of their work’s limitations and implications.

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Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. A new paper engineers a communication network between cells using DNA instead. .” Jessica Hamzelou for MIT Technology Review.

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Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. A new paper engineers a communication network between cells using DNA instead. .” Jessica Hamzelou for MIT Technology Review.

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Codon

APRIL 9, 2023

The CAR-T cells were detectable in 26 out of 27 children after 30 months. Of those, 17 children responded to the treatment, and the 3-year overall survival rate was 60 percent. Read Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial. Nature Cell Biology. McGrady N.R. Shenderov E.

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Codon

APRIL 9, 2024

In response to the precipitous rise in incidence, governments on both sides of the Pacific began a systematized search for antimalarial treatments. Over the course of 12 years, the Walter Reed Army Institute of Research (WRAIR) screened more than 250,000 compounds in search of an efficacious treatment. Nobody had an answer.

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Codon

SEPTEMBER 22, 2024

They achieved this by treating mouse fetal ovaries with an enzyme mixture to break them apart into single cells, isolating the ovarian supporting cells, and mixing them with human PGC-like cells to form aggregates, which were then cultured in liquid media for up to 120 days.

DNA 106

DNA Laboratories Regulations Therapies 106

Broad Institute

NOVEMBER 21, 2024

Researchers identify source of a brain cancer’s deadly transformation By Corie Lok November 21, 2024 Breadcrumb Home Researchers identify source of a brain cancer’s deadly transformation Slow-growing glioma tumors become more aggressive when their cells shift identities and acquire new genetic mutations.

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Drug Target Review

APRIL 1, 2025

Advances in biotechnology are driving significant progress in the treatment of rare diseases, making it possible to develop targeted therapies for previously untreatable conditions. His expertise has positioned SynaptixBio to advance its drug candidates toward clinical trials.

Disease 52

Disease Therapies Clinical Trials Cell Biology 52

SugarCone Biotech

MAY 28, 2019

Learnings regarding immune geography and cell:cell contact are increasingly important as we consider how best to advance cell therapies for diverse hematologic malignancies and solid tumors ( www.aletabio.com ). Therefore, TILs are not always terminally exhausted.

Immune Response 52

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Codon

APRIL 16, 2023

Nature Cell Biology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read Safety and dose escalation of the targeted oncolytic adenovirus OBP-301 for refractory advanced liver cancer: Phase I clinical trial. Cell Reports. Nature Biotechnology. Nature Protocols.

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Drug Target Review

MARCH 26, 2025

Hormone replacement therapy (HRT) for low hormone levels is one of the oldest treatments utilised in Western medicine and can be traced back centuries. 2 Sex hormone replacement also gained in popularity, notably starting in 1940, when conjugated equine oestrogen was approved for the treatment of postmenopausal women. Ann Intern Med.

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Codon

NOVEMBER 1, 2024

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. This essay focuses on how we might do both, specifically for the cell. Even the humble E.

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