Drug Target Review

JANUARY 31, 2024

For instance, clinical trial diversity is essential to Allergan Aesthetics to ensure our clinical trials appropriately reflect the changing landscape of the aesthetics consumer. Additionally, organizations need to help ensure representation of the diverse populations they serve throughout all facets of their work.

Clinical Trials 97

Clinical Trials Production Science Research 97

The Pharma Data

OCTOBER 27, 2021

million expansion will bring high quality seeds to worldwide markets faster, providing solutions for growers and meeting consumer demands / The seven-hectare global Product Design Center in San Nicolás includes state-of-the-art lab space for cell biology research and greenhouses for seed production.

Cell Biology 40

Cell Biology Production Laboratories Marketing 40

Drug Target Review

AUGUST 24, 2023

Her discoveries on the first-in-class RNA-based innate immune receptor agonist RGT100, built the foundation for the initiation of a Phase I clinical trial as well as the successful acquisition of Rigontec by MSD (known as Merck & Co. Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration.

Treatment 98

Treatment Therapies Clinical Development Cell Biology 98

The Pharma Data

DECEMBER 1, 2020

Innate has been a pioneer in the understanding of natural killer cell biology and has expanded its expertise in the tumor microenvironment and tumor-antigens, as well as antibody engineering.

Cell Biology 52

Cell Biology Clinical Trials Production Licensing 52

The Pharma Data

JANUARY 3, 2021

Both will help NexImmune advance current early-stage clinical trials and will guide Company’s translational efforts to develop new immunotherapy products. Both Jerry and Jeff have proven and successful track records in the design and execution of early and late-stage clinical trials that have evaluated novel immune therapies.

Immune Response 40

Immune Response Clinical Trials Therapies Cell Biology 40

The Pharma Data

JANUARY 23, 2021

Assessing the morphological and architectural changes in collagen fibers with the platform could potentially aid TNBC clinical trials in categorizing patients and monitoring therapeutic responses. SINGAPORE , Jan. Particularly in TNBC, collagen remodeling is seen in the stromal compartment [ 3 ].

Treatment 52

Treatment Cell Biology Hospitals Clinical Trials 52

DrugBank

JUNE 27, 2023

Modern advances in “omics,” as well as biomarker development, clinical trial design, and mathematical modelling (including artificial intelligence) have revolutionized our ability to precisely define or “stratify” patient populations, splitting them into groups based on their characteristics.

Disease 98

Disease Treatment Drugs Clinical Trials 98

Drug Target Review

MAY 21, 2024

I don’t think that it’s harder for women to enter careers in STEM, at least not in the scientific field—cell biology—that I have predominantly worked in. Organoids are being used in more and more clinical trials.

Doctors 59

Doctors Science Research Cell Biology 59

The Pharma Data

JANUARY 4, 2021

Innate has been a pioneer in the understanding of natural killer cell biology and has expanded its expertise in the tumor microenvironment and tumor-antigens, as well as antibody engineering.

Drugs 40

Drugs Cell Biology Pharmacokinetics Clinical Trials 40

Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. By then, a few cancer immunotherapies had entered clinical trials and only a handful had been approved by the FDA.

Research 137

Research Immune Response Clinical Trials Therapies 137

Drug Target Review

OCTOBER 2, 2024

By harvesting, expanding, and injecting CD34+ cells directly to the heart muscle, this natural repair mechanism is enhanced. Early-phase clinical trials have shown the safety and efficacy of using stem cells for cardiac repair, encouraging further research and development.

Therapies 98

Therapies Disease Engineering RNA 98

The Pharma Data

OCTOBER 19, 2020

We welcome them to our team and I am confident in our collective abilities to execute this large late-stage trial enrolling up to 1,600 patients with sepsis and acute kidney injury.”. in Cell Biology from Utrecht University. Dr. Kraan joins AM-Pharma from Pierre Fabre S.A., Dr. van de Laar holds a M.Sc. About AM-Pharma.

Trials 40

Trials Small Molecule Cell Biology Clinical Trials 40

Codon

APRIL 9, 2024

After confirming they experienced no side effects, Tu and her colleagues carried out the first clinical trial on human patients in Hainan between August and October 1972, which continued to demonstrate qinghao extract’s high efficacy. Few journal articles were written about the project using her (or anyone’s) name before 2010.

Drugs 140

Drugs Science Research Doctors 140

Drug Target Review

JUNE 29, 2023

It’s great that we are in clinical trials, and we are helping a certain number of patients, but if you don’t make it to the market and all that involves, then you haven’t really won because you think of all those patients that you’re no longer serving if you don’t get to that end goal.

Therapies 115

Therapies Science Production Cell Biology 115

Codon

OCTOBER 22, 2024

Detailed guidelines have been developed for randomized clinical trials ( CONSORT , STAR-D ), observational studies ( STROBE ), genetic association studies ( STREGA ), and meta-analyses ( PRISMA ). The implementation of CLAIM has benefited the journal’s readership and is pushing the field in a much-needed direction.

Science 115

Science Research Government Cell Biology 115

Precision for Medicine

APRIL 7, 2023

This provides value to researchers executing clinical trials, particularly those developing novel therapeutics and vaccines, where sample processing requires geographical proximity to the trial site and samples need to be processed within hours of collecting them from patients. Canada, Europe, and Australia.

Laboratories 52

Laboratories Clinical Research Clinical Trials Cell Biology 52

Codon

APRIL 2, 2023

Read Safety and pharmacokinetics of escalating doses of neutralising monoclonal antibody CAP256V2LS administered with and without VRC07-523LS in HIV-negative women in South Africa (CAPRISA 012B): a phase 1, dose-escalation, randomised controlled trial. An open-source FACS automation system for high-throughput cell biology.

DNA 52

DNA RNA Engineering Licensing 52

The Pharma Data

MARCH 11, 2021

Second, the biorevolution is driving innovation in all of Bayer’s divisions – with major progress in cell biology, gene editing and data science. And third, the company is accelerating its transformation and further increasing efficiency.

Science 52

Science Pharmaceuticals Licensing Licensing 52

Drug Target Review

DECEMBER 21, 2023

Where do you see the future of mRNA biology and AI converging, and how does Anima Biotech plan to lead this convergence? mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer.

Disease 105

Disease Small Molecule Vaccine Drugs 105

Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. A new paper engineers a communication network between cells using DNA instead. .” difficile therapy.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. A new paper engineers a communication network between cells using DNA instead. .” difficile therapy.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 9, 2023

Read Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial. Read Hematopoietic stem-cell gene therapy is associated with restored white matter microvascular function in cerebral adrenoleukodystrophy. Nature Cell Biology. McGrady N.R. Molecular Therapy. Shenderov E. Nature Medicine.

Therapies 52

Therapies RNA Engineering Vaccine 52

Codon

SEPTEMBER 22, 2024

They achieved this by treating mouse fetal ovaries with an enzyme mixture to break them apart into single cells, isolating the ovarian supporting cells, and mixing them with human PGC-like cells to form aggregates, which were then cultured in liquid media for up to 120 days.

DNA 117

DNA Laboratories Regulations Therapies 117

The Pharma Data

NOVEMBER 17, 2021

Realizing that their research could be relevant to inflammation associated with COVID-19, the duo reached out to Chris Sander, professor in residence of cell biology at HMS. A small randomized phase 2 clinical trial of disulfiram in patients with moderate COVID-19 is nearing completion, and another is underway.

Virus 52

Virus Drugs Clinical Trials Medical Schools 52

Drug Target Review

APRIL 1, 2025

Co-founder and CEO Dr Dan Williams brings over 20 years of experience in biochemistry and drug development, with a strong background in research and clinical trials. His expertise has positioned SynaptixBio to advance its drug candidates toward clinical trials. Gene silencing has been shown to have fewer side effects than gene editing.”

Disease 52

Disease Therapies Clinical Trials Cell Biology 52

Codon

APRIL 16, 2023

Nature Cell Biology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read Safety and dose escalation of the targeted oncolytic adenovirus OBP-301 for refractory advanced liver cancer: Phase I clinical trial. Nature Biotechnology. coli DNA using a Retro-Cascorder.

Engineering 52

Engineering DNA RNA Science 52

Drug Target Review

JANUARY 16, 2025

Phase III trials for MK-0616 commenced in the second half of 2023. 9,10 Because many therapeutic macrocycles violate the Ro5 guidelines, the presumption was that such large molecules would have limited cell permeability. Phase 2b randomized trial of the oral PCSK9 inhibitor MK-0616. 8 Why are there not more macrocyclic drugs?

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52

Broad Institute

NOVEMBER 21, 2024

Bernstein is also chair of the Department of Cancer Biology at Dana-Farber Cancer Institute, a professor in cell biology and pathology at Harvard Medical School, and holds the Richard and Nancy Lubin Family Chair. Inevitable progression Gliomas arise from glial cells, which protect and support a healthy nervous system.

Research 124

Research Medical Schools DNA Hospitals 124

Drug Target Review

MARCH 26, 2025

Sigilon uncovers possible reason behind haemophilia A trial hold. She has a background in cell biology, biophysics and pharmacology and was a professor and Chair at the University of Kansas for over 20 years. Testoerone in men with hypogonadism and transgender males: a systematic review comparign three different preparatiosn.

Therapies 52

Therapies Compliance Treatment Small Molecule 52

SugarCone Biotech

MAY 28, 2019

Learnings regarding immune geography and cell:cell contact are increasingly important as we consider how best to advance cell therapies for diverse hematologic malignancies and solid tumors ( www.aletabio.com ). Therefore, TILs are not always terminally exhausted.

Immune Response 52

Immune Response Therapies Engineering Drug Development 52

Codon

NOVEMBER 1, 2024

.” However, it isn’t clear that such a superintelligence could even be applied to its full potential in biology today, given the dearth of high-quality datasets needed to train it. Still, many of the bottlenecks slowing biology today are biophysical , rather than computational. Subscribe to Asimov Press. Even the humble E.

DNA 128

DNA RNA Molecular Biology Laboratories 128