Clinical Development Clinical Pharmacology Process Chemistry 
Metabolite Tales Blog
JULY 5, 2023
With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [9] PHARMACOLOGY/TOXICOLOGY NDA REVIEW AND EVALUATION.
Metabolite Tales Blog
JULY 5, 2023
With metabolic stability in mind, we take a look at the metabolism of some FDA approved synthetic macrocyclic drugs, and a few of those that were/are in clinical development where metabolism data was available. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [9] PHARMACOLOGY/TOXICOLOGY NDA REVIEW AND EVALUATION.
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