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During clinicaldevelopment, new chemical entities (NCEs) require an absorption, metabolism, and excretion (AME) study. As a result, we ensure collection of all urine and fecal samples over a period ranging between five to seven days, modifying the participant diet if needed.
Addressing the long timelines and high costs of drugdevelopment is therefore critical for the advancement of medical innovation. Unfortunately, many drug candidates fail. Clinicaldevelopment failure may be due to an inability to demonstrate efficacy or sufficient safety. Unfortunately, many drug candidates fail.
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