Agency IQ

APRIL 12, 2024

Cell-based assays , while more complex to develop and use, offer another option for characterizing product activity at a slightly higher level, allowing sponsors to measure the further downstream effects of products (e.g., morphological cell changes or alterations in protein production or expression).

Production 40

Production FDA Therapies Biochemical Assays 40

Codon

MARCH 20, 2023

🧪 Papers AI + Bio Protein-specific signal peptides for mammalian vector engineering. Evolutionary-scale prediction of atomic-level protein structure with a language model. Biological Engineering Generation of functional oocytes from male mice in vitro. Metabolic Engineering. Metabolic Engineering.

Virus 52

Virus Engineering RNA Small Molecule 52

Codon

MARCH 24, 2024

In the first real test of delivering a complex biomolecule to over a billion people, little has changed from how Genentech first approached manufacturing in the 1980s; Cells are genetically engineered and then grown in steel tanks. To make matters worse, many companies struggled with engineering problems on the path to scale.

Engineering 87

Engineering Vaccine Production RNA 87

The Pharma Data

JANUARY 24, 2021

Dr Caroline Barelle (CEO and CSO, Elasmogen Ltd) explained: “These robust little proteins have their origins in the immune systems of sharks and over 400 million years of evolution have been tailor-made to recognise pockets and grooves in proteins as part of the animals defence against infections.

Research 40

Research Virus Medical Schools Government 40