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Using gene therapy to live longer, healthier lives

Drug Discovery World

She discusses with DDW’s Megan Thomas the company’s lead programme; a gene therapy called ER-100. This is the sweet spot for developing therapeutics where you can restore cells to a more youthful state, while maintaining cell identity.” Sharon Rosenzweig-Lipson , PhD, is Chief Scientific Officer of Life Biosciences.

Therapies 147
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Macrophage cell therapy: a new hope for chronic liver disease patients

Drug Target Review

Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years. Could you describe the platform of macrophage biology and cell engineering used by Resolution Therapeutics in developing their cell therapies?

Therapies 114
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Precision cancer therapies: Where are we?

Drug Discovery World

DDW’s Diana Spencer reports on the recent Avacta Therapeutics Science Day, which explored the latest exciting developments in targeted treatments for cancer and asked what advances the future might bring. Komanduri suggested synthetic biology could increase efficacy of CAR-T cell therapy in the future.He

Therapies 130
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Turning Science into Business: Inducing autophagy to treat disease

Drug Discovery World

What is the potential for this type of therapy in treating other neurodegenerative disorders? DS: Why do you think there haven’t been any therapies targeting autophagy before? Could therapies like these treat rare genetic conditions? What impact could autophagy inducing therapies have on lifespan? LinkedIn profile.

Disease 130
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Cell and gene therapies: Opportunities for innovation 

Drug Discovery World

In recent years the advanced therapy industry has been the most significant disruptor in medicine. Cell and gene therapies are not only transforming the way diseases are treated but are also aiming to cure entirely new patient populations. Record breaking investments in 2021 fuel an industry on fire . billion raised.

Therapies 130
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Transcending expectations for cell & gene therapy development

Drug Discovery World

David Lewandowski, Business Director of Cell & Gene Therapy at Azenta Life Sciences, explains how efficient sample management can help to work efficiently and bring therapies to market faster. It has been estimated that by 2025 the FDA will be approving 10 to 20 cell and gene therapy products per year 2.

Therapies 130
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Expert view: What’s next for cell and gene therapy?

Drug Discovery World

What are the global innovations in cell and gene therapy? What opportunities and challenges are emerging and can therapies get to market faster? The deeper the understanding of product and process from a characterisation standpoint, the smoother the regulatory conversations and development pathway will be.” The solution?

Therapies 130