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Metabolism of macrocyclic drugs

Metabolite Tales Blog

We await to see what other biotransformation data emerges on synthetic macrocycles as more information is publicly disclosed as they advance through development. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry.

Drugs 52
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Metabolism of de novo designed macrocyclic drugs

Metabolite Tales Blog

We await to see what other biotransformation data emerges on synthetic macrocycles as more information is publicly disclosed as they advance through development. Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry.