Drug Discovery World

APRIL 25, 2023

“We have reached an important milestone with the dosing of the second participant in our clinical trial evaluating a potentially groundbreaking CAR-T cell therapy to cure HIV,” said Mehrdad Abedi, Professor of Internal Medicine, Hematology and Oncology and co-investigator of the study. “So In 2021 there were an estimated 1.5

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Drug Discovery World

SEPTEMBER 16, 2022

A biologic therapy for very young children with moderate to severe eczema (or atopic dermatitis) has been shown to be safe and effective in an international trial. Arkwright said: “Young children and infants who have moderate-to-severe eczema have a substantially reduced quality of life.

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Drug Discovery World

FEBRUARY 9, 2023

1 This authorisation by the MHRA has been issued under Project Orbis, an international programme coordinated by the US Food and Drug Administration (FDA), which provides a framework for the concurrent submission and review of oncology medicines among international partners. Whilst this disease is uncommon, the incidence is rising.

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Drug Target Review

SEPTEMBER 5, 2024

I am a pharmacist by training and continued with a PhD in Clinical Pharmacology. However, my goal was all the time to work with drug development in the pharma industry, so I moved on and started that journey in 1992 when I took on a role as Clinical Research Manager at AstraHässle, a mid-size Swedish pharma company.

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PPD

JUNE 7, 2023

Adults aren’t the only patients affected by the increasing prevalence of liver disease. The number of pediatric patients diagnosed with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is on the rise, yet there are currently no approved therapies to treat NAFLD and NASH in adult or pediatric populations.

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The Pharma Data

MAY 6, 2021

INDIANAPOLIS , May 6, 2021 /PRNewswire/ — With a goal of integrating data and technology to help streamline diabetes management, Eli Lilly and Company (NYSE: LLY) signed strategic international agreements with four companies – DexCom, Inc., Glooko Inc. ” About Diabetes An estimated 463 million adults worldwide 1 have diabetes. .”

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Drug Discovery World

OCTOBER 20, 2022

DDW Multimedia Editor Megan Thomas takes a broad look at the drug discovery and development landscape in Japan and highlights how it is bolstered by government policies, investment, collaboration, start-up ecosystems and academic research. . Overview . Start-up ecosystem . Japan is evolving with such ecosystems.

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The Pharma Data

NOVEMBER 10, 2020

Biomarkers will be critical to developing precision medicine for Alzheimer’s disease. Although a few are out there, phosphorylated tau (P-tau) may enable even earlier and more accurate detection, according to Eli Lilly-associated researchers speaking at the Clinical Trials on Alzheimer’s Disease (CTAD) virtual conference in early November.

Disease 52

Disease Clinical Trials Trials Research 52

Drug Discovery World

DECEMBER 26, 2023

Makoto Inoue, President and Representative Director of Otsuka Pharmaceutical commented: “Otsuka is committed to the development of drugs for rare diseases such as autosomal dominant polycystic kidney disease (ADPKD). His research focuses on immunotherapies for patients with breast cancer.

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The Pharma Data

JANUARY 25, 2021

“The establishment of an Advisory Board focusing on Alzheimer’s disease, and the recruitment of such an impressive group of scientific and clinical leaders in this field is an extremely important step forward for the Company,” stated Paul Brennan, NervGen’s President & CEO. Dr.

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Drug Discovery World

APRIL 29, 2024

Current areas of attention include post-traumatic stress disorder (PTSD), palliative care, agitation in Alzheimer’s disease, spasticity in multiple sclerosis, inflammatory skin conditions, Tourette syndrome, idiopathic hypersomnia, and potential activation in immunotherapy treatments in oncology 2,3. Ann Intern Med. link] Feb 1, 2022.

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Drug Discovery World

JULY 1, 2024

Following a trip to Copenhagen, Denmark, DDW’s Megan Thomas reflects on the Novo Nordisk Foundation’s efforts to tackle cardiometabolic diseases. The World Health Organization (WHO) reports that cardiovascular diseases (CVDs) are the leading cause of death globally, stating that an estimated 17.9

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Vial

JUNE 18, 2024

Recognizing the issue of underrepresentation of racial and ethnic minorities in clinical trials, e.g., for Alzheimer’s Disease (AD), researchers have sought to understand the barriers and facilitators for patient access better. Although AD disproportionately affects U.S. Specifically, U.S. Specifically, U.S. Rubin et al.

Clinical Trials 52

Clinical Trials Trials Clinical Research Research 52

Vial

MARCH 25, 2024

Worldwide Clinical Trials is a mid-size, full-service global contract research organization (CRO) that works with biotech and pharma to advance new medications. With an international presence in nearly 60 countries, Worldwide is supported by over 3,400 team members.

Clinical Trials 52

Clinical Trials Trials Clinical Development Clinical Research 52

The Pharma Data

JUNE 26, 2021

Together with our research partners, BIG conducts landmark, practice-changing trials that can have a significant impact on the lives of women with breast cancer,” sa id David Cameron , Chair of the BIG Executive Board. Adjuvant therapy helps prevent and delay the progression of disease into the later setting.

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Clinical Trials International Trials Therapies 52

PPD

OCTOBER 9, 2023

Education on the disease state and regular reinforcement. Travel services: A patient in a rare disease trial contacted her concierge expressing concern about her ability to travel to her appointments, as she and her husband shared a vehicle. Training through a device and/or app to support protocol requirements.

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Vial

APRIL 10, 2024

The strong commitment to innovation allows IQVIA to provide advanced analytics, technology solutions, and industry-specific expertise in the health information technologies and clinical research domains. IQVIA has a vast collection of healthcare information, including over 1.2 increase on a reported basis and an 4.8%

Clinical Trials 52

Clinical Trials Trials Compliance Clinical Research 52

The Pharma Data

NOVEMBER 10, 2020

P otential to be a safer and effective alternative to the intravenous immunotherapies currently used for Crohn’s Disease. Crohn’s Disease Therapeutics Market Size $4.7 Phase1b/2 clinical study to be conducted in the United States and several European countries. Billion by 2025. and Europe.

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Clinical Trials Science Disease Trials 40

Olympian Clinical Research

SEPTEMBER 3, 2020

The tough thing about depression is that the disease is wildly indiscriminate, affecting patients of every age, gender, and ethnicity. For patients that struggle with depression, the disease can have devastating impacts both mentally, physically, and emotionally.

Clinical Trials 98

Clinical Trials Treatment Clinical Research Trials 98

Vial

MAY 8, 2024

A Brief Introduction Medrio was founded in 2005 with the mission to revolutionize clinical research with the creation of the first cloud-based EDC system, designed to simplify data collection without requiring advanced programming skills. Established in 2020, Vial has rapidly emerged as a leading technology-driven CRO.

Clinical Trials 52

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Drug Discovery World

JANUARY 24, 2023

In the study, published in PLoS Computational Biology , scientists got one step closer to a breakthrough owing to a first-of-its-kind computer model that successfully simulated a clinical trial evaluating the efficacy of multiple treatments for Alzheimer’s disease.

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Clinical Trials Trials Drugs Treatment 242

Drug Discovery World

OCTOBER 16, 2023

A company within this ecosystem is STORM Therapeutics, a clinical stage biotechnology company creating novel small molecule therapies that inhibit RNA modifying enzymes (RME) for use in oncology and other diseases. The university aims to identify treatments for life-threatening anti-microbial diseases and metabolic disorders.

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The Pharma Data

MARCH 17, 2022

Merck (NYSE: MRK), known as MSD outside the United States and Canada, the European Organisation for Research and Treatment of Cancer (EORTC) and the European Thoracic Oncology Platform (ETOP) today announced results from the pivotal Phase 3 KEYNOTE-091 trial, also known as EORTC-1416-LCG/ETOP-8-15 – PEARLS. About EORTC. About ETOP.

Therapies 52

Therapies Clinical Trials Disease Trials 52

The Pharma Data

NOVEMBER 1, 2020

Dr Nurbhai has more than 25 years of experience and a strong track record in the strategic and operational leadership of all phases of clinical research and development at companies across Europe and the US. The Company is managed by a team with broad international, commercial and clinical-science experience.

Clinical Pharmacology 52

Clinical Pharmacology Small Molecule Clinical Research Science 52

Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. Consequently, this strategy substantially reduces the failure rate of cancer clinical trials. International Clinical Trials Registry Platform (ICTRP).

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PerkinElmer

JANUARY 21, 2022

Dementias include a wide spectrum of neurodegenerative disorders, including Parkinson’s disease, Motor Neuron diseases, Multiple Sclerosis, Huntington’s disease, Creutzfeldt–Jakob disease, and Alzheimer’s disease. That’s right, the MRC says. To achieve that, Prof. I believe that is a goal worth pursuing.”

Cell Biology 52

Cell Biology Disease Treatment Science 52

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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Drug Discovery World

SEPTEMBER 28, 2022

Whilst we know that AI has been effective in practices such as validating targets that may be suitable to treat a disease, it faces a plethora of significant challenges. Which areas of drug discovery research stand to benefit most? . But has its application been as revolutionary as industry bods predicted? . The simple answer is no.

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The Pharma Data

JANUARY 6, 2021

“Further, PDE4-inhibition is a well-documented pharmacological target for a number of other inflammatory indications, and we look forward to advancing our clinical research to realize the full potential of orismilast for the benefit of the millions of patients living with inflammatory conditions globally,” adds Professor Sommer.

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Conversations in Drug Development Trends

APRIL 3, 2024

Leveraging Real-World Data : Utilizing electronic health records and disease registries can help identify potential candidates more efficiently. Partnering with advocacy organizations can help them to explain radiopharmaceuticals to their members and encourage participation.

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Trials Clinical Trials Compliance Treatment 81

The Pharma Data

MARCH 17, 2021

KEYTRUDA reduced the risk of disease progression or death by 35% (HR=0.65 [95% CI, 0.48-0.88]; We are driven to advance therapies to help improve outcomes for patients with blood cancers, including those with relapsed or refractory classical Hodgkin lymphoma, through our broad clinical program.”. months versus 8.3 months (95% CI, 10.9-19.4)

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Therapies Treatment Disease Trials 52

The Pharma Data

JANUARY 14, 2021

Dickstein enjoyed 30 years in the pharmaceutical field before retiring in 1998 as the vice president of clinical research for Transcend Therapeutics, Inc. As a seasoned scientist, Dr. Dickstein spent significant time conducting research. Early in his career, Dr. Dickstein held appointments with the U.S.

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Laboratories Clinical Research Hospitals Pharmaceuticals 52

Drug Discovery World

AUGUST 3, 2023

For example, the FDA has not approved a marketing application for cannabis for the treatment of any disease or condition to date 1. Susan Audino is ISO Assessor and Instructor, Scientific Advisor at AOAC International CASP, and Chemistry Laboratory Consultant at SA Audino & Associates, LLC. deletion syndrome.

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Clinical Trials Regulations Production FDA 130

The Pharma Data

DECEMBER 27, 2020

Orelabrutinib is a BTK inhibitor developed by InnoCare for the treatment of cancer and autoimmune diseases. Professor and Director of the Department of Internal Medicine and Lymphoma, Peking University Cancer Hospital. “We China represents a large pharmaceutical market. 1 Source: [link].

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Hospitals Science Treatment Clinical Trials 52

The Pharma Data

OCTOBER 26, 2020

University International Institute for Global Health (UNU-IIGH). The topics covered in the BMJ series, include a broad range of social and medical factors influencing women’s health, such as sexual and reproductive health; violence against women, mental health, noncommunicable diseases, climate change, limited.

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Government Disease Clinical Research International 52

The Pharma Data

FEBRUARY 18, 2022

The global mRNA technology transfer hub was established in 2021 to support manufacturers in low- and middle-income countries to produce their own vaccines, ensuring that they have all the necessary operating procedures and know-how to manufacture mRNA vaccines at scale and according to international standards.

Vaccine 52

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The Pharma Data

JANUARY 17, 2021

It was co-sponsored by Merck and Bayer, conducted with the scientific oversight of the Canadian VIGOUR Centre and the Duke Clinical Research Institute. Myelosuppression happens when radiation damages internal organs, including bone marrow. Aurinia Pharmaceutical’s Voclosporin for Lupus Nephritis.

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FDA Small Molecule Immune Response Hospitals 52