Quanticate

JULY 5, 2024

It’s essential for maintaining ethical standards, high-quality outcomes and facilitating global standardisation, enabling multi-center and multinational studies, thereby streamlining the development and approval process for new medical treatments, and maintaining public trust in clinical research.

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Olympian Clinical Research

SEPTEMBER 3, 2020

Eating a well balanced diet, full of fruits and vegetables, floods your body with antioxidants that then decrease the internal inflammation contributing to and/or caused by depression. . We just started a clinical trial to explore a new treatment option for patients who suffer from moderate to severe depression.

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PPD

DECEMBER 16, 2024

The drug development industry faces rising costs and increasingly complex protocols as top challenges, with 49% of developers citing costs as their primary concern and 39% pointing to protocol complexity as a key hurdle, according to a recent survey of 150 drug developers worldwide by the PPD clinical research business of Thermo Fisher Scientific.

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PPD

JUNE 7, 2023

As therapies for the treatment of NASH in adult patients go this year to the U.S. Food and Drug Administration (FDA) for approval , much work remains for drug developers aiming to advance treatments for pediatric populations. We are poised to use our expertise to advance your treatment.

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PPD

AUGUST 5, 2024

Though they do positively impact patients’ quality of life and hemodynamic parameters, these treatments — prostacyclin analogs and receptor agonists, phosphodiesterase 5 inhibitors, endothelin-receptor antagonists, and cGMP activators — have shown limited beneficial effects on survival and disease progression.

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Alta Sciences

SEPTEMBER 13, 2023

Four Pain Models Altasciences Uses to Assess Treatments During Clinical Trials pmjackson Wed, 09/13/2023 - 17:01 September is pain awareness month, and the importance of pain management and continued research into effective analgesics is integral to helping patients suffering from various pain conditions.

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Drug Target Review

SEPTEMBER 5, 2024

I am a pharmacist by training and continued with a PhD in Clinical Pharmacology. However, my goal was all the time to work with drug development in the pharma industry, so I moved on and started that journey in 1992 when I took on a role as Clinical Research Manager at AstraHässle, a mid-size Swedish pharma company.

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Drug Target Review

JULY 6, 2023

Animal testing plays a significant role in pre-clinical research and therefore requires the use of millions of animals. 1 Over a quarter of those were for basic research purposes, with most common areas focused on the immune system, the nervous system and oncology. In Britain, 2.88

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The Pharma Data

MAY 6, 2021

INDIANAPOLIS , May 6, 2021 /PRNewswire/ — With a goal of integrating data and technology to help streamline diabetes management, Eli Lilly and Company (NYSE: LLY) signed strategic international agreements with four companies – DexCom, Inc., This creates a solid foundation enabling collaboration and confident treatment decisions.

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Conversations in Drug Development Trends

AUGUST 9, 2024

It broadens recruitment strategies, diversifies the patient population, and expands the study population, thus increasing access to potentially life-saving treatments. These trials increase the chances of success by enabling the early detection of effective treatments in defined populations and focusing efforts on the most promising options.

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The Pharma Data

DECEMBER 7, 2020

. “I thought we’d find a greater number of trials in the later years of the study,” said lead author Dr. Alexander Zheutlin, a resident physician in the department of internal medicine at the University of Utah in Salt Lake City. This impedes our ability to develop new and novel interventions and treatments.”

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The Pharma Data

JUNE 26, 2021

Together with our research partners, BIG conducts landmark, practice-changing trials that can have a significant impact on the lives of women with breast cancer,” sa id David Cameron , Chair of the BIG Executive Board. Adjuvant therapy helps prevent and delay the progression of disease into the later setting.

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PPD

OCTOBER 9, 2023

Adverse event identification: A patient called his concierge stating that he had been experiencing severe nausea while on treatment and would need to leave the trial. The concierge expressed empathy for the participant’s symptoms, and then offered to transfer the participant to his clinical trial site.

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Conversations in Drug Development Trends

APRIL 3, 2024

By: Sue Batchelor, Executive Director, Oncology Project Management Radiopharmaceuticals represent a cutting-edge frontier in oncology treatment, offering the promise of highly targeted therapy with the potential to revolutionize cancer care. One such approach is standardizing imaging protocols across your trial sites — consistency is key.

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Advarra

OCTOBER 15, 2024

The International Council for Harmonisation (ICH) good clinical practice (GCP) guidelines are critical in ensuring the safety and rights of clinical trial participants. The post The Evolution of Clinical Quality: Key Considerations from ICH E6 R3 appeared first on Advarra.

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Vial

JUNE 12, 2024

Utilizing PROs enables the active participation of patients in their care outcomes – both in a clinical setting and in clinical research. PROs in clinical trials are important as they capture the patient’s perspective and ensure that the impact of an intervention is comprehensively evaluated.

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The Pharma Data

JANUARY 6, 2021

7, 2021 /PRNewswire/ — UNION therapeutics A/S ( UNION ) today announces that the US Food and Drug Administration (FDA) has approved an Investigational New Drug program (IND) for oral orismilast; a next generation PDE4-inhibitor for the treatment of plaque psoriasis in adults. One step closer to a novel treatment.

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The Pharma Data

DECEMBER 24, 2020

The results add to similar findings and support regulatory and clinical recommendations that patients shouldn’t stop taking ACE inhibitors or ARBs due to concerns about increased COVID-19 risk, the study authors said. ” © 2020 HealthDay.

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The Pharma Data

DECEMBER 27, 2020

Treatment with orelabrutinib has demonstrated clear benefit for patients. Orelabrutinib is a BTK inhibitor developed by InnoCare for the treatment of cancer and autoimmune diseases. We believe that the approval of orelabrutinib will provide a safe and effective new treatment solution for lymphoma patients in China.”.

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The Pharma Data

NOVEMBER 1, 2020

Dr Nurbhai has more than 25 years of experience and a strong track record in the strategic and operational leadership of all phases of clinical research and development at companies across Europe and the US. The Company is managed by a team with broad international, commercial and clinical-science experience.

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The Pharma Data

JANUARY 14, 2021

We are strongly encouraged by these data and the potential for a frontline targeted treatment that can improve overall survival,” said Zev A. Associate Professor of Medicine at UCLA, Co-director of the Gastrointestinal Oncology Program and Director of Early Phase Clinical Research at the Jonsson Comprehensive Cancer Center.

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Vial

MAY 15, 2024

Vial | Pros and Cons The unprecedented consequences of the COVID-19 pandemic gave rise to the advent of decentralized clinical trials (DCTs), which are studies that use telemedicine and remote or local healthcare professionals to enable participants to join from different locations. billion and now functions as a subsidiary.

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Conversations in Drug Development Trends

NOVEMBER 3, 2022

BioPharma Dive interviewed our Derek Ansel on how to conduct psychedelic clinical research. In April 2022, the Food and Drug Administration (FDA) issued draft guidance on developing a “Race and Ethnicity Diversity Plan” for clinical trials. So while Ansel said he’s seen many sponsors of orphan drugs successfully diversify U.S.

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The Anticancer Fund

OCTOBER 18, 2023

Proteogenomic insights suggest druggable pathways in endometrial carcinoma Published in Cancer Cell This large, international study used a multi-omics approach to characterise a prospectively collected cohort of 130 endometrial carcinoma tumour samples and 20 normal controls. You can easily subscribe to this newsletter by clicking here.

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The Pharma Data

JANUARY 14, 2021

Dr. Dickstein enjoyed 30 years in the pharmaceutical field before retiring in 1998 as the vice president of clinical research for Transcend Therapeutics, Inc. As a seasoned scientist, Dr. Dickstein spent significant time conducting research. Early in his career, Dr. Dickstein held appointments with the U.S.

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PerkinElmer

JANUARY 21, 2022

1 To address the urgent need for new therapies, the UK’s Medical Research Council (MRC), a national public agency supporting health science and research, established the Dementias Platform United Kingdom (DPUK) in 2014. References Spotlight on: Dementia – Research – Medical Research Council [Internet].

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Advarra

SEPTEMBER 30, 2022

Is the clinical research industry winning or failing at innovation? Despite the fast pace of medical innovation, the lack of consistency between technology systems managing these advancements ultimately inhibits research progress. . Has innovation really succeeded in clinical research if this is the state we’re currently in?

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The Pharma Data

JANUARY 13, 2021

We are pleased vaccines are now approved for the prevention of COVID-19; however, a significant unmet need remains for effective treatments for symptomatic patients. Ensifentrine has been well tolerated in clinical trials involving more than 1,300 people. About the study. Single center study at University of Alabama at Birmingham.

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Vial

MARCH 27, 2024

The Costs of Working with a CRO Running clinical trials is an integral part of the pharmaceutical industry, crucial to the development and approval of new drugs and treatments. Personnel salaries, site rentals, and equipment maintenance are other necessary expenses associated with clinical trials.

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Advarra

JUNE 20, 2023

Complicated Conditions and Targeted Treatments Cancer treatment is moving toward more targeted therapies: As researchers identify cancer molecular pathways and targets, it’s becoming possible to treat the target tumor regardless of the organ of origin. This means study startup times can vary greatly.

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Vial

JUNE 18, 2024

Black/African American and Hispanic/Latino adults in terms of prevalence, incidence, and outcomes, these populations are underrepresented in AD clinical research. Both groups agreed that reluctance toward research is a prominent barrier. Although AD disproportionately affects U.S. Specifically, U.S.

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Vial

FEBRUARY 15, 2024

Sponsors often contract a CRO to delegate specific day-to-day tasks, streamlining their research processes and enhancing efficiency. Patient recruitment and retention : Recruiting and retaining a sufficient number of eligible participants is one of the major challenges in conducting clinical trials.

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The Anticancer Fund

NOVEMBER 16, 2022

Top stories Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in limb-salvage surgery for osteosarcoma: A retrospective analysis Published in Medicine Osteosarcoma remains desperately in need of new treatment options, as has been noted here before.

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Drug Target Review

OCTOBER 25, 2024

How does precision neuroscience differ from traditional approaches in the treatment of neurodegenerative diseases, and what advantages does it offer? Traditionally, Alzheimer’s disease is diagnosed by clinical examination, medical history and cognitive testing. link] Devi, G. 2023, July 24). link] Cummings J. Adv Exp Med Biol.

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The Pharma Data

APRIL 22, 2023

The trial is the first-in-human clinical study investigating the duoCAR T-cell therapy for the treatment of HIV. “So far, there have been no adverse events observed that were related to the treatment and the two participants are doing fine.” An additional nine subjects may enroll in the expansion cohort.

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Advarra

OCTOBER 1, 2024

Managing clinical trial budgets efficiently is necessary for the success and sustainability of clinical research sites. Escalation plans: Use internal and sponsor escalation plans to navigate any challenges arising during the negotiation process. from the Food and Drug Administration [FDA]) Safety reporting (e.g.,

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The Pharma Data

JULY 29, 2021

The series of promising pipeline updates included the data from the landmark ZUMA-7 study for the treatment of second-line large B-cell lymphoma. Gilead presented additional lenacapavir clinical development program data at the International AIDS Society (“IAS”) 2021 Conference on HIV Science. Viral Diseases.

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