Alta Sciences

SEPTEMBER 13, 2023

Four Pain Models Altasciences Uses to Assess Treatments During Clinical Trials pmjackson Wed, 09/13/2023 - 17:01 September is pain awareness month, and the importance of pain management and continued research into effective analgesics is integral to helping patients suffering from various pain conditions.

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Drug Discovery World

APRIL 25, 2023

The trial is the first-in-human clinical study investigating the duo CAR-T cell therapy for the treatment of HIV. “We So far, there have been no adverse events observed that were related to the treatment and the two participants are doing fine.”

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Quanticate

JULY 5, 2024

It’s essential for maintaining ethical standards, high-quality outcomes and facilitating global standardisation, enabling multi-center and multinational studies, thereby streamlining the development and approval process for new medical treatments, and maintaining public trust in clinical research.

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Drug Discovery World

OCTOBER 20, 2022

DDW Multimedia Editor Megan Thomas takes a broad look at the drug discovery and development landscape in Japan and highlights how it is bolstered by government policies, investment, collaboration, start-up ecosystems and academic research. . Overview . Start-up ecosystem . Japan is evolving with such ecosystems.

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Conversations in Drug Development Trends

JANUARY 24, 2024

Many parents are hesitant to pursue testing since it will not affect the patient’s care management, as several of these diseases have no approved treatments, such as Fragile X, a syndromic form of autism. Throughout my research, I discovered that genetic counselors are more likely to discuss clinical trials with rare disease patients.

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Drug Discovery World

JULY 5, 2023

Precision oncology supports targeted therapeutic treatments by determining the specific molecular characteristics of a tumour – the molecular phenotype, as it’s called – to obtain an in depth understanding of the patient’s unique cancer and using it to specifically target the patient’s cancer on a molecular level.

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Drug Discovery World

MAY 17, 2024

Deepika Khedekar , Associate Centralized Clinical Trial Lead at IQVIA Inc, looks at the challenges of utilising artificial intelligence (AI) in oncology clinical research. That brings us to our next question – so what problems can AI solve in oncology research? So, what does this mean for clinical trials in oncology?

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PPD

JUNE 7, 2023

As therapies for the treatment of NASH in adult patients go this year to the U.S. Food and Drug Administration (FDA) for approval , much work remains for drug developers aiming to advance treatments for pediatric populations. We are poised to use our expertise to advance your treatment.

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Drug Target Review

SEPTEMBER 5, 2024

I am a pharmacist by training and continued with a PhD in Clinical Pharmacology. However, my goal was all the time to work with drug development in the pharma industry, so I moved on and started that journey in 1992 when I took on a role as Clinical Research Manager at AstraHässle, a mid-size Swedish pharma company.

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Conversations in Drug Development Trends

AUGUST 9, 2024

It broadens recruitment strategies, diversifies the patient population, and expands the study population, thus increasing access to potentially life-saving treatments. These trials increase the chances of success by enabling the early detection of effective treatments in defined populations and focusing efforts on the most promising options.

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Drug Discovery World

APRIL 29, 2024

Current areas of attention include post-traumatic stress disorder (PTSD), palliative care, agitation in Alzheimer’s disease, spasticity in multiple sclerosis, inflammatory skin conditions, Tourette syndrome, idiopathic hypersomnia, and potential activation in immunotherapy treatments in oncology 2,3. Ann Intern Med. link] Feb 1, 2022.

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The Pharma Data

MAY 6, 2021

INDIANAPOLIS , May 6, 2021 /PRNewswire/ — With a goal of integrating data and technology to help streamline diabetes management, Eli Lilly and Company (NYSE: LLY) signed strategic international agreements with four companies – DexCom, Inc., This creates a solid foundation enabling collaboration and confident treatment decisions.

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Drug Discovery World

DECEMBER 26, 2023

Atropos Health and SEQSTER Real-world data company Atropos Health and SEQSTER, a provider of patient-centric healthcare data technology, have partnered to accelerate patient registries in clinical research. The collaboration will advance the speed-to-insight for many underrepresented populations served by registry-based research.

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The Pharma Data

JUNE 26, 2021

Together with our research partners, BIG conducts landmark, practice-changing trials that can have a significant impact on the lives of women with breast cancer,” sa id David Cameron , Chair of the BIG Executive Board. Adjuvant therapy helps prevent and delay the progression of disease into the later setting.

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The Pharma Data

DECEMBER 7, 2020

. “I thought we’d find a greater number of trials in the later years of the study,” said lead author Dr. Alexander Zheutlin, a resident physician in the department of internal medicine at the University of Utah in Salt Lake City. This impedes our ability to develop new and novel interventions and treatments.”

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Olympian Clinical Research

SEPTEMBER 3, 2020

Eating a well balanced diet, full of fruits and vegetables, floods your body with antioxidants that then decrease the internal inflammation contributing to and/or caused by depression. . We just started a clinical trial to explore a new treatment option for patients who suffer from moderate to severe depression.

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Drug Discovery World

APRIL 14, 2023

She is also a Professor of Pathology at the Johns Hopkins University School of Medicine, Co-director of the Skip Viragh Center for Pancreas Cancer Clinical Research and Patient Care, and Deputy Director of the Johns Hopkins Institute for Clinical and Translational Research.

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Advarra

OCTOBER 1, 2024

Managing clinical trial budgets efficiently is necessary for the success and sustainability of clinical research sites. Escalation plans: Use internal and sponsor escalation plans to navigate any challenges arising during the negotiation process. from the Food and Drug Administration [FDA]) Safety reporting (e.g.,

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Drug Discovery World

AUGUST 3, 2023

For example, the FDA has not approved a marketing application for cannabis for the treatment of any disease or condition to date 1. million for the STEP (Stratification & Treatment in Early Psychosis) programme, as part of its support for mental health research.

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Drug Discovery World

JANUARY 24, 2023

In the study, published in PLoS Computational Biology , scientists got one step closer to a breakthrough owing to a first-of-its-kind computer model that successfully simulated a clinical trial evaluating the efficacy of multiple treatments for Alzheimer’s disease. How will a treatment fit into the existing competitive landscape?

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Conversations in Drug Development Trends

APRIL 3, 2024

By: Sue Batchelor, Executive Director, Oncology Project Management Radiopharmaceuticals represent a cutting-edge frontier in oncology treatment, offering the promise of highly targeted therapy with the potential to revolutionize cancer care. One such approach is standardizing imaging protocols across your trial sites — consistency is key.

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PPD

OCTOBER 9, 2023

Adverse event identification: A patient called his concierge stating that he had been experiencing severe nausea while on treatment and would need to leave the trial. The concierge expressed empathy for the participant’s symptoms, and then offered to transfer the participant to his clinical trial site.

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Drug Discovery World

OCTOBER 16, 2023

The university aims to identify treatments for life-threatening anti-microbial diseases and metabolic disorders. One of the research themes at the university is Discovery of Medicines, which hosts the Cancer Research UK Newcastle Drug Discovery Unit.

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Conversations in Drug Development Trends

NOVEMBER 3, 2022

BioPharma Dive interviewed our Derek Ansel on how to conduct psychedelic clinical research. In April 2022, the Food and Drug Administration (FDA) issued draft guidance on developing a “Race and Ethnicity Diversity Plan” for clinical trials. So while Ansel said he’s seen many sponsors of orphan drugs successfully diversify U.S.

Disease 52

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Vial

MARCH 27, 2024

The Costs of Working with a CRO Running clinical trials is an integral part of the pharmaceutical industry, crucial to the development and approval of new drugs and treatments. Personnel salaries, site rentals, and equipment maintenance are other necessary expenses associated with clinical trials.

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Vial

JUNE 18, 2024

Black/African American and Hispanic/Latino adults in terms of prevalence, incidence, and outcomes, these populations are underrepresented in AD clinical research. Both groups agreed that reluctance toward research is a prominent barrier. Although AD disproportionately affects U.S. Specifically, U.S.

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The Pharma Data

JANUARY 6, 2021

7, 2021 /PRNewswire/ — UNION therapeutics A/S ( UNION ) today announces that the US Food and Drug Administration (FDA) has approved an Investigational New Drug program (IND) for oral orismilast; a next generation PDE4-inhibitor for the treatment of plaque psoriasis in adults. One step closer to a novel treatment.

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Vial

FEBRUARY 15, 2024

Sponsors often contract a CRO to delegate specific day-to-day tasks, streamlining their research processes and enhancing efficiency. Patient recruitment and retention : Recruiting and retaining a sufficient number of eligible participants is one of the major challenges in conducting clinical trials.

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The Pharma Data

MARCH 17, 2022

Merck (NYSE: MRK), known as MSD outside the United States and Canada, the European Organisation for Research and Treatment of Cancer (EORTC) and the European Thoracic Oncology Platform (ETOP) today announced results from the pivotal Phase 3 KEYNOTE-091 trial, also known as EORTC-1416-LCG/ETOP-8-15 – PEARLS. About EORTC. About ETOP.

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Drug Discovery World

AUGUST 8, 2022

Earlier this year, pharmaceutical company Novo Nordisk announced positive results from Phase I & II clinical trials investigating its antibody treatment for haemophilia A. . We look forward to moving into phase 3 clinical development, which is due to commence in Q4 2022.

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The Pharma Data

DECEMBER 24, 2020

The results add to similar findings and support regulatory and clinical recommendations that patients shouldn’t stop taking ACE inhibitors or ARBs due to concerns about increased COVID-19 risk, the study authors said. ” © 2020 HealthDay.

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Advarra

JUNE 20, 2023

Complicated Conditions and Targeted Treatments Cancer treatment is moving toward more targeted therapies: As researchers identify cancer molecular pathways and targets, it’s becoming possible to treat the target tumor regardless of the organ of origin. This means study startup times can vary greatly.

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The Pharma Data

MARCH 17, 2021

This approval is based on results from the pivotal Phase 3 KEYNOTE-204 trial, in which KEYTRUDA monotherapy demonstrated a significant improvement in progression-free survival (PFS) compared with brentuximab vedotin (BV), a commonly used treatment. KEYTRUDA reduced the risk of disease progression or death by 35% (HR=0.65 [95% CI, 0.48-0.88];

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The Pharma Data

JANUARY 14, 2021

We are strongly encouraged by these data and the potential for a frontline targeted treatment that can improve overall survival,” said Zev A. Associate Professor of Medicine at UCLA, Co-director of the Gastrointestinal Oncology Program and Director of Early Phase Clinical Research at the Jonsson Comprehensive Cancer Center.

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The Pharma Data

DECEMBER 27, 2020

Treatment with orelabrutinib has demonstrated clear benefit for patients. Orelabrutinib is a BTK inhibitor developed by InnoCare for the treatment of cancer and autoimmune diseases. We believe that the approval of orelabrutinib will provide a safe and effective new treatment solution for lymphoma patients in China.”.

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The Pharma Data

NOVEMBER 1, 2020

Dr Nurbhai has more than 25 years of experience and a strong track record in the strategic and operational leadership of all phases of clinical research and development at companies across Europe and the US. The Company is managed by a team with broad international, commercial and clinical-science experience.

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PerkinElmer

JANUARY 21, 2022

1 To address the urgent need for new therapies, the UK’s Medical Research Council (MRC), a national public agency supporting health science and research, established the Dementias Platform United Kingdom (DPUK) in 2014. References Spotlight on: Dementia – Research – Medical Research Council [Internet].

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