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Applying Artificial Intelligence to Transform the Patient Enrollment Paradigm in Clinical Research

PPD

The benefits of utilizing AI in clinical research Patient recruitment and diversity AI is increasingly being utilized in the recruitment process for clinical trials , aiming to connect individuals with potential benefits from investigational treatments.

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PPD Early Development Services: Accelerating the Clinical Process

PPD

Our early development organization expanded offerings in Phase Ib patient trials to characterize the pharmacokinetics and pharmacodynamics in patients and to assess safety and early efficacy signals. We have three PPD clinical research units, located in Austin, Texas , Orlando, Florida , and Las Vegas, Nevada.

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Up Close and Personal with Jason Boehme, Associate Director, Program Management

Alta Sciences

He was promoted to Associate Director, Program Management , in 2022, and now oversees a team of program managers who guide end-to-end solutions, including preclinical , clinical , CDMO , regulatory , and bioanalytical solutions. What Was your dream job as a child?

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Establishing Effective Adaptive Trial Designs for Oncology in Multi-Regional Studies

Conversations in Drug Development Trends

Advantages and Operational Challenges in Adaptive MRCTs Adaptive trial designs are gaining popularity in clinical research due to their ability to improve trial efficiency and uphold ethical standards, resulting in faster and more reliable outcomes.

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Targeting the immunotherapy potential of cytokines IL-12 and IL-18 with new advancements in protein engineering

Drug Target Review

We are currently selecting our lead IL-18 variant on the basis of potency for the IL-18 receptor, optimal pharmacokinetic profile and in vivo efficacy for inhibiting tumour growth. Ultimately, our goal is for this approach to yield an enhanced cancer fighting response.

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Altasciences Completes Successful Phase I Trial of Ischemix’ Novel Compound for Treatment of Traumatic Brain Injury (TBI)

Alta Sciences

The trial was performed at Altasciences’ clinical facility in Montréal. The Phase I trial was performed to evaluate safety, tolerability, and pharmacokinetics in a group of 80 healthy participants in a two-part, double-blind, placebo-controlled study.

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Keys to Success in Vaccine Development for Special Populations

PPD

From study participants’ consent, to minimizing the patient and caregiver burden, to planning for different needs at different stages of the pediatric immune system, there are many factors to consider when conducting clinical research with this specific population.

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