Drug Target Review

JULY 12, 2023

Molecular-level biochemical assays like transcriptomics, genomics and proteomics have emerged as valuable tools for identifying potential targets in cancer treatment through deep cyclic inhibition (DCI). How does the DCI mechanism compare to the design of other drugs for cancer treatment?

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PPD

OCTOBER 17, 2024

In China, the high incidence of solid tumors is driving an urgent need for advanced therapies, spurring the push for new treatment approaches. Site selection presents barriers and opportunities As cell therapies expand in Asia-Pacific, areas with large hospitals are often the main hubs for innovation.

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National Drug & Alcohol Research Centre Blog

JULY 13, 2021

NCCRED was funded through the Strategy, and commenced in 2018, to build clinical research capacity and work towards establishing evidence-based treatment approaches for both methamphetamines and other emerging drugs of concern. Why do a clinical research priority setting study?

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Vial

DECEMBER 4, 2023

Clinical research is an integral component of the healthcare ecosystem. It is pivotal in the development of cutting-edge treatments, therapies, and interventions for a wide array of diseases. Patient Payments in Clinical Research: Perception Over the Years In the U.S.,

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Conversations in Drug Development Trends

JANUARY 24, 2024

Much of what we discuss I covered in my presentation, “Leveraging Genetics to Support Rare Disease Clinical Trials,” at last year’s World Orphan Drug Congress (WODC) EU. One diagnostic example that I discussed in my presentation is autism.

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Olympian Clinical Research

NOVEMBER 16, 2022

In its early stages, HS often presents as a small, pea-sized lump in one place. More research is still needed to understand the causes of HS fully. Receiving an accurate and prompt diagnosis of HS is essential for developing a treatment plan and preventing it from worsening. Treatments for Hidradenitis Suppurativa.

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FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.

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The Pharma Data

MARCH 11, 2021

Eli Lilly and Company (NYSE: LLY) today announced that data from programs across its oncology portfolio and pipeline will be presented at the 2021 American Association for Cancer Research (AACR) Annual Meeting, to be held virtually April 10-15, 2021. Portfolio Highlights. Pipeline Highlights.

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PPD

AUGUST 5, 2024

Though they do positively impact patients’ quality of life and hemodynamic parameters, these treatments — prostacyclin analogs and receptor agonists, phosphodiesterase 5 inhibitors, endothelin-receptor antagonists, and cGMP activators — have shown limited beneficial effects on survival and disease progression.

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The Pharma Data

SEPTEMBER 10, 2020

Full data from the Phase 3 CROWN study in lung cancer will be presented during the Presidential Symposium. Data to be presented include findings from the Phase 3 CROWN study of LORBRENA ® (lorlatinib)* in first-line ALK-positive non-small cell lung cancer (NSCLC), building on Pfizer’s extensive heritage in precision medicine research.

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The Pharma Data

JANUARY 14, 2021

(NASDAQ: FPRX) today announced clinical results from the global, randomized, double-blind placebo-controlled Phase 2 FIGHT trial evaluating first-in-class targeted therapy bemarituzumab in advanced gastric or gastroesophageal junction (GEJ) cancer. The ASCO GI presentation slides are available on the company’s website. Wainberg, M.D.,

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The Pharma Data

JANUARY 14, 2021

COHASSET, MA, January 14, 2021 /24-7PressRelease/ — Marquis Who’s Who, the world’s premier publisher of biographical profiles, is proud to present Harvey Leonard Dickstein, MD, with the Albert Nelson Marquis Lifetime Achievement Award. As a seasoned scientist, Dr. Dickstein spent significant time conducting research.

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Drug Target Review

AUGUST 22, 2023

This Q&A explores how pre-clinical research is being used to identify potential therapies for Huntington’s disease, a devastating condition that currently lacks disease- modifying treatments. What makes the potential therapeutic for Huntington’s disease unique compared to other treatments?

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PPD

NOVEMBER 7, 2023

The underrepresentation of diverse groups in clinical research is an area of regulatory, scientific and industry focus, partly due to the recent U.S. Food and Drug Administration (FDA) draft guidance, “Diversity Plans to Improve Enrollment of Participants from Underrepresented Racial and Ethnic Populations in Clinical Trials.”

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Olympian Clinical Research

JULY 12, 2022

There are several types of depression, each with its own set of symptoms and recommended treatment methods. Major depressive disorder ( MDD ), also known as clinical depression, is characterized by a persistent feeling of sadness or emptiness lasting for at least two weeks. As a result, many people do not seek treatment.

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Conversations in Drug Development Trends

JUNE 21, 2024

The 2024 ASCO Annual Meeting from the American Society of Clinical Oncology is a fantastic platform for clinical researchers to discuss the latest advancements and challenges in oncology research. Currently, there are 12 approved ADC drugs, and several hundred more are in the development pipeline.

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The Pharma Data

APRIL 12, 2022

20% variant allele frequency reduction – At the time of analysis with > 2 year follow up the survival estimate was 100% in patients who had improvements in bone marrow fibrosis or variant allele frequency – Results were presented at the American Association for Cancer Research annual meeting.

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Olympian Clinical Research

AUGUST 19, 2022

While these conditions cannot be cured, there are treatments available that may lessen the symptoms. In addition, clinical research may provide new information and breakthrough treatments. . Therefore finding treatment options that may help lessen the symptoms is important. . Treatment Options for Pediatric Eczema.

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The Pharma Data

MAY 27, 2022

In the pivotal clinical study CARTITUDE-1, 98 percent of patients with relapsed or refractory multiple myeloma responded to a one-time treatment with ciltacabtagene autoleucel and 80 percent of patients who responded experienced a stringent complete response . to develop and commercialise cilta-cel.[1].

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The Pharma Data

JANUARY 12, 2021

a biopharmaceutical company focused on the development of first-in-class therapeutics for the treatment of cancer, today announced the completion of the Phase 1b clinical trial conducted by the NCI with its lead clinical candidate zotiraciclib (ZTR/TG02), a potent oral cyclin-dependent kinase 9 (CDK9) inhibitor.

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Olympian Clinical Research

DECEMBER 19, 2023

Understanding its triggers, identifying symptoms, exploring home remedies, and reviewing advanced medical treatments are crucial for effective management. With ongoing research and clinical trials , institutions like Olympian Clinical Research are at the forefront of finding innovative treatment options.

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The Pharma Data

JANUARY 10, 2021

SH ) submitted its pivotal phase III clinical trial application (IND) of national class I innovative drug Chiauranib to NMPA, for the treatment of Small Cell Lung Cancer (SCLC) as a single agent for the patients after 2nd-line systemic chemotherapy and recurrence afterwards. (Chipscreen Biosciences, Stock Symbol: 688321.SH

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PPD

JUNE 24, 2024

Explore the unique aspects of mega trials, the challenges they pose to vaccine developers, what the future holds for these large, complex trials, and how a partnership with an experienced provider of clinical research solutions can enable success.

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PPD

SEPTEMBER 7, 2023

For more than 40 years, drug developers have been dedicated to advancing HIV clinical research in the quest for treatments and, ultimately, a cure. Though there has been considerable progress in treatment options, 39 million people across the globe are infected with HIV, with an estimated 1.3 Since the U.S.

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Conversations in Drug Development Trends

AUGUST 9, 2024

It broadens recruitment strategies, diversifies the patient population, and expands the study population, thus increasing access to potentially life-saving treatments. These trials increase the chances of success by enabling the early detection of effective treatments in defined populations and focusing efforts on the most promising options.

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Olympian Clinical Research

MARCH 31, 2022

In order to receive the right treatment for your condition, it’s essential to know what type of anxiety you’re experiencing. These symptoms can cause impairment throughout one’s daily life, and GAD is diagnosed when three or more symptoms are present more days than not for at least six months. What is General Anxiety Disorder?

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Olympian Clinical Research

SEPTEMBER 16, 2021

Plaque psoriasis presents itself as patches of red, raised skin covered with silvery scales, along with a red bulbous base. Psoriasis Treatment Options. Once psoriasis is diagnosed, treatment is determined based on the level of severity and if there is a presence of joint involvement, known as psoriatic arthritis.

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Conversations in Drug Development Trends

MARCH 12, 2024

From their use in risk and safety assessments to patient screening and treatment efficacy, biomarkers offer minimally invasive, objective data. Deviations from established baseline values provide insights into treatment response in certain cancer indications. Currently, there are thousands of known biomarkers.

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Olympian Clinical Research

DECEMBER 1, 2022

The type of psoriasis you experience can influence the symptoms and complications associated with your condition as well as the treatment plan that is right for you. Potential treatment options include phototherapy, corticosteroids, and oral medications. Guttate psoriasis usually responds well to topical treatments and phototherapy. .

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The Pharma Data

OCTOBER 19, 2020

Two presentations will be delivered by Nanobiotix and two will be delivered by the University of Texas MD Anderson Cancer Center. The Company is also engaged in a broad, comprehensive clinical research collaboration with The University of Texas MD Anderson Cancer Center to further expand the NBTXR3 development program.

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The Pharma Data

NOVEMBER 11, 2020

Details of the presentation are as follows: Event: Late Breaking Developments, Part II Title: One Year and Beyond: Long-term Multiple-dose Study of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate with Extended Durability, in wAMD, DME, and RVO Presenter: Arshad M Khanani, M.D., Chief Executive Officer.

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Drug Target Review

MAY 7, 2024

However, some biomarkers may only be present in a minority of patients, requiring a large patient population to identify such markers. Moreover, the application of synthetic control arms presents the opportunity to transform the trial process itself. Not all biomarkers have a limited prevalence.

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Conversations in Drug Development Trends

NOVEMBER 10, 2023

At this year’s annual Pain Therapeutics Summit , which took place in San Diego, CA, October 19 to 20th, I heard brilliant presentations on novel pain medication development, targeted discoveries, pain classifications, the NIH HEAL Initiative , trial designs, biomarkers, and others.

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Olympian Clinical Research

JULY 7, 2021

It’s perfectly normal for people to get nervous in certain social situations, such as someone who’s worried about an upcoming interview for a job or dreading a class presentation. The post Understanding The Signs & Symptoms Of Social Anxiety appeared first on Olympian Clinical Research. Social Anxiety & Avoidance.

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PPD

JUNE 29, 2023

Although several corticosteroid treatments are available as first-line treatments, drug developers continue to seek more effective therapies to improve the wellbeing of those diagnosed with atopic dermatitis. But developing treatments for atopic dermatitis is complex and competitive.

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The Pharma Data

SEPTEMBER 21, 2020

. MSD (Merck) and Eisai have revealed new data from two trials under the LEAP clinical programme evaluating the combination of MSD’s PD-1 inhibitor Keytruda and Eisai’s oral tyrosine kinase inhibitor Lenvima. However, the combo treatment performed better in certain cancers compared to others, reporting a response in 32.3%

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The Premier Consulting Blog

NOVEMBER 30, 2022

It can augment preclinical and clinical research through mechanistic and predictive investigations that would otherwise be impossible. Virtual patients are then generated who can be randomized to one or more cohorts to allow researchers to select treatment options.

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