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Results from a phase 1/2 clinicaltrial of a novel stem cell treatment for cornea injuries found 14 patients treated and tracked for 18 months had a more than 90% success rate at restoring the cornea's surface and improvements in vision.
A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinicaltrial without the intoxication typically associated with whole plant cannabis. For the study, researchers conducted the first human clinicaltrial investigating the acute effects of CBG on anxiety, stress and mood.
Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinicaltrial.
Recent results from a recent clinicaltrial indicate that a twice-yearly injection of Lenacapavir offers an overall 96% reduced risk of acquiring HIV. This makes Lenacapavir significantly more effective than the standard daily oral PrEP (pre-exposure prophylaxis).
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinicaltrials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. As AI-driven innovation reshapes the clinicaltrial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. But its impact goes far beyond research.
MONDAY, July 15, 2024 -- An experimental drug appears to help women deal with stress incontinence, clinicaltrial data show.The drug, for now dubbed TAS-303, reduced the frequency of leaks related to stress incontinence by about 58%, compared with.
The scientists say that discovering the mechanism will support ongoing clinicaltrials, and could lead to the targeted use of aspirin to prevent the spread of susceptible types of cancer, and to the development of more effective drugs to prevent cancer metastasis.
As clinicaltrials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Discover how AI is used to optimize key aspects of clinicaltrial management.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management.
FRIDAY, April 19, 2024 -- Black and Hispanic patients with Alzheimer’s disease are greatly underrepresented in clinicaltrials, even though they’re more likely to get dementia than whites.However, racial discrimination may not be driving this.
Food and Drug Administration (FDA) has approved the first-ever clinicaltrials testing pig kidney transplants in people with kidney failure, marking a major step forward in cross-species transplantation.Two. TUESDAY, Feb. 4, 2025 -- The U.S.
Decentralized clinicaltrials (DCTs) bring many benefits to the clinical research process, and more importantly, the patients. However, it is important to remember the risks if there is no data security process in place.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinicaltrials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies.
Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.
Fortunately, technology has created opportunities to innovate in clinicaltrials for rare diseases. The need for more research into rare diseases is clear, but researchers face significant challenges.
A non-addictive pain pill faces its definitive test, while study results in ALS, a rare heart disease and lung cancer could have far-reaching implications.
Clinicaltrial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management.
TUESDAY, April 1, 2025 -- Fasting every other day can prompt more weight loss than simply cutting calories, a new clinicaltrial shows.People who undertook 4:3 intermittent fasting lost just under 8% of their body weight within a year, compared to.
TUESDAY, June 27, 2023 -- An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinicaltrials shows. Retatrutide helped people with obesity drop about.
Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.
However, recent breakthroughs in AI, such as predictive modelling, clinicaltrial optimisation, and personalised medicine, have demonstrated its potential. At the heart of Unlearns approach is the use of AI to improve clinicaltrials, especially in phases two and three.
About 79% of clinicaltrial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a new article.
There are many common reasons clinicaltrials fail, including failure to demonstrate efficacy, safety concerns, issues with inclusion and exclusion criteria and patient recruitment. Follow these five steps to increase the odds of clinicaltrial success.
One may choose to participate in a clinicaltrial for many reasons. However, deciding to enroll in a clinicaltrial is only one part of the process. Volunteering often has multiple benefits, from advancing medical research to gaining access to cutting-edge medical care.
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinicaltrial.
Researchers have discovered that an FDA-approved epilepsy drug can prevent or slow the growth of NF1-linked optic gliomas in mice, laying the groundwork for a clinicaltrial.
The findings suggest -- for the first time in a clinicaltrial -- that early treatment to remove amyloid plaques from the brain many years before symptoms arise can delay the onset of Alzheimer's dementia.
An efficacy endpoint in oncology is a characteristic or variable that measures how beneficial a treatment is to a patient’s feeling, function, and survival in a clinicaltrial. They are essential for assessing whether new cancer therapies are safe and efficacious [1].
A group of independent experts wasn't convinced by clinicaltrial data from company Lykos Therapeutics, which is seeking FDA approval of MDMA-assisted treatment for post-traumatic stress disorder.
How can small and mid-sized biotech companies better manage pharmacovigilance during clinicaltrials? Listen to the podcast to learn how strategic alliances are helping.
MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinicaltrial findings report. In all, 36% of children treated with.
In recent years, the pharmaceutical industry has increasingly harnessed artificial intelligence (AI) to make clinicaltrials more efficient and effective. By making patient selection and recruitment processes more targeted, AI-driven tools not only improve trial outcomes but also accelerate the journey of new drugs to market.
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