Remove Clinical Trials Remove Molecular Biology Remove Trials
article thumbnail

Logistics in Focus: Orchestrating the Challenges of Cell Therapy

Conversations in Drug Development Trends

These advanced therapeutics harness the power of molecular biology to improve human health. Despite their exciting potential, the smooth operation of cell therapy development trials requires extraordinary orchestration, perfectly aligning the product and patient journeys.

article thumbnail

Organoids: the versatile platform for discovery and regeneration

Drug Target Review

Imagine being able to create an in vitro replica of a diseased organ to study the molecular mechanism underlying the illness. Now take a step further: envision testing drugs in these organoids to identify the ones that can treat disease safely and effectively without needing to run expensive clinical trials first.

Treatment 105
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

De-risking drug discovery with predictive AI

Broad Institute

Still, more than 90 percent of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Molecular Biology of the Cell. Many drugs fail because they simply aren’t safe. A fourth is in the works. DOI: 10.1021/acs.chemrestox.4c00015. Seal S, et al. Online February 2, 2024.

article thumbnail

A surprising new role for a major immune regulator

Broad Institute

Drugs that activate STING have been developed and tested in clinical trials as cancer immunotherapy drugs that would help stimulate the immune system to destroy tumors. Food and Drug Administration has not approved any STING agonist thus far, although multiple clinical trials are currently underway.

article thumbnail

Sarah Wicks Returns to HPM to Elevate Drug Development and Regulatory Practice

FDA Law Blog: Drug Discovery

Her expertise spans a range of critical areas including: human subject protections, clinical trial conduct, development strategies, FDA interactions, and enforcement action responses. Sarah graduated with a cum laude degree in Cell and Molecular Biology from Towson University, a M.P.H.

article thumbnail

Scaling Phage Therapy

Codon

1 Yet even after more than two decades of research, media hype, and dozens of clinical trials and biotech start-ups that have come and gone, phage therapy has not scaled. 2 The specificity issue also makes it difficult to test phage therapies in a conventional clinical trial. Still, researchers are trying. aeruginosa, S.

Therapies 124
article thumbnail

What is the largest CRO in the US?

Vial

Growth factors for this market included the growing size of the pharmaceutical industry, the increasing number of clinical trials , substantial funds dedicated to pharma and biotech R&D, and the growing biosimilars and generics market. By geographical region, the global CRO services market in 2023 was dominated by North America.