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Advancements in screening technologies for small-molecule drug discovery including cellular assays, computational screening, and biophysics-based methods enhanced by structural biology breakthroughs have improved screeninghit rates and facilitated the identification of drug candidates for previously undruggable targets.
The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinicaltrials. The team that I lead within the CCDD is called the Hit Discovery and Structural Design Team.
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