Drugs.com

JUNE 25, 2024

TUESDAY, June 25, 2024 -- An experimental stem cell therapy can essentially cure type 1 diabetes by restoring insulin production in some patients, early clinical trial results show.Seven out of 12 patients no longer needed daily insulin shots after.

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BioPharma Drive: Drug Pricing

DECEMBER 11, 2023

Editas had the tall task Monday of convincing ASH attendees its gene therapy for sickle cell disease could improve on Casgevy and Lyfgenia.

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Clinical Trials Trials Therapies Disease 300

Science Daily: Pharmacology News

MAY 8, 2024

The study provides both mechanistic and preclinical evidence supporting the rapid initiation of clinical trials for patients with acute myeloid leukemia (AML) to test an existing medicine that inhibits the complex, called eganelisib, both alone and in combination with the most used AML chemotherapy, cytarabine.

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Therapies Clinical Trials Trials 303

BioPharma Drive: Drug Pricing

JUNE 27, 2023

A Duchenne gene therapy faces a crucial test, while highly anticipated study results are expected in lung cancer, obesity and heart disease.

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Clinical Trials Trials Therapies Disease 293

Drugs.com

JUNE 12, 2023

MONDAY, June 12, 2023 -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and successful in four patients. Two of the patients were treated at Cleveland Clinic Children’s in.

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Therapies Disease Clinical Trials Trials 264

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.People with hemophilia B saw their bleeding episodes. THURSDAY, Sept.

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Therapies Trials Clinical Trials Treatment 246

BioPharma Drive: Drug Pricing

JUNE 4, 2024

A group of independent experts wasn't convinced by clinical trial data from company Lykos Therapeutics, which is seeking FDA approval of MDMA-assisted treatment for post-traumatic stress disorder.

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FDA FDA Approval Clinical Trials Therapies 329

Drugs.com

JUNE 7, 2023

TUESDAY, June 6, 2023 -- Radiation therapy might not be necessary in treating some forms of rectal cancer and lymphoma, sparing patients from the toxic treatment, a pair of new clinical trials shows. One trial found that rectal cancer patients.

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Therapies Clinical Trials Trials Treatment 246

Science Daily: Pharmacology News

AUGUST 30, 2023

A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.

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Therapies Clinical Trials Trials Disease 221

Science Daily: Pharmacology News

JANUARY 24, 2024

A novel gene therapy for hearing loss was administered to six children in China in a clinical trial. Each child had an inherited deafness caused by mutations in the OTOF gene, called DFNB9.

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Therapies Clinical Trials Trials Research 220

Drugs.com

DECEMBER 15, 2023

15, 2023 -- Patients with advanced heart failure can benefit from stem cell therapy, a large, new clinical trial has found.Injections of stem cells programmed to heal damaged heart tissue wound up improving overall quality of life for. FRIDAY, Dec.

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Therapies Clinical Trials Trials 245

BioPharma Drive: Drug Pricing

SEPTEMBER 27, 2023

Expert advisers to the agency voted 17-1 that Brainstorm's clinical trial data did not show the company's stem cell treatment was effective for treating ALS.

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Therapies Clinical Trials FDA Trials 284

Drug Target Review

DECEMBER 20, 2024

However, recent breakthroughs in AI, such as predictive modelling, clinical trial optimisation, and personalised medicine, have demonstrated its potential. At the heart of Unlearns approach is the use of AI to improve clinical trials, especially in phases two and three.

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Clinical Trials Trials Pharmaceuticals Drug Development 128

BioPharma Drive: Drug Pricing

SEPTEMBER 27, 2023

Expert advisers to the agency voted 17-1 that Brainstorm's clinical trial data did not show the company's stem cell treatment was effective for treating ALS.

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Therapies Clinical Trials FDA Trials 274

Science Daily: Pharmacology News

FEBRUARY 22, 2024

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

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Therapies Clinical Trials Treatment Disease 226

Drugs.com

DECEMBER 21, 2023

21, 2023 -- A new treatment appears to reduce food allergies in children and teens, according to interim clinical trial results.A THURSDAY, Dec. lab-made monoclonal antibody called omalizumab (Xolair) significantly increased the amounts of common.

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Clinical Trials Therapies Trials Treatment 260

Antidote

JULY 13, 2022

Before a potential new therapy can be administered to patients, it must go through several clinical trial phases designed to test the drug or device for safety and effectiveness. For many new treatments, it will take approximately ten years for the therapy to progress from initial discovery to being approved.

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Clinical Trials Trials Therapies Treatment 134

Drug Target Review

FEBRUARY 10, 2025

In the rapidly advancing field of cell therapies, Dr Jason Bock has emerged as a leader, known for his innovative approach to optimising the development process. With over 25 years of experience in therapeutics, Bock has played a pivotal role in shaping the future of cell therapies, particularly through his work at CTMC.

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Therapies Treatment Engineering Clinical Trials 65

Drugs.com

OCTOBER 22, 2024

22, 2024 -- At-home brain stimulation therapy can safely and effectively treat severe to moderate depression, a new clinical trial shows.Rates of treatment response and depression remission were three times higher in people receiving. TUESDAY, Oct.

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Treatment Clinical Trials Therapies Trials 279

Drugs.com

JUNE 27, 2024

THURSDAY, June 27, 2024 -- Acupuncture can help breast cancer patients deal with the hot flashes that often accompany hormone therapy, a new clinical trial says.Nearly 2 in 3 women who got acupuncture during hormone therapy reported fewer and less.

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Clinical Trials Treatment Therapies Trials 263

Science Daily: Pharmacology News

MARCH 7, 2024

Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to new research.

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Treatment Clinical Trials Therapies Trials 323

Antidote

APRIL 4, 2024

Before it is released onto the market, the development of any new drug or medical device must undergo rigorous testing , part of which involves clinical trials. Clinical trials are integral to making sure that any new therapy is both safe and effective for individuals, and volunteers are a vital part of the process.

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Clinical Trials Trials Therapies Marketing 119

Antidote

NOVEMBER 9, 2023

Before any new treatment or therapy is able to be used by the patient population, it must go through the process of a clinical trial — this is the case for any new prescription drug, but also true for over-the-counter medications, medical devices, and more.

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Clinical Trials Trials Therapies Treatment 126

Drugs.com

SEPTEMBER 14, 2023

14, 2023 -- A new study is adding to evidence that the party drug "ecstasy" can boost the benefits of talk therapy for people suffering from post-traumatic stress disorder (PTSD). In a clinical trial, researchers found that three. THURSDAY, Sept.

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Clinical Trials Therapies Trials Research 279

Conversations in Drug Development Trends

NOVEMBER 12, 2024

By Amy Raymond, PhD, PMP, Executive Director, Therapeutic Strategy Lead, Rare Disease Cell and gene therapies (CGTs) include cutting-edge approaches that offer the hope of a healthier, happier, and better tomorrow for a wide range of patient populations. Operationalizing these trials requires proactive and flawless management at every stage.

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Therapies Clinical Supply Clinical Trials Trials 72

Quanticate

NOVEMBER 21, 2024

An efficacy endpoint in oncology is a characteristic or variable that measures how beneficial a treatment is to a patient’s feeling, function, and survival in a clinical trial. They are essential for assessing whether new cancer therapies are safe and efficacious [1].

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Clinical Trials Trials Therapies Treatment 98

Science Daily: Pharmacology News

AUGUST 18, 2023

Novel stem cell therapy called a CALEC transplant was performed safely in four patients with serious chemical burns tracked in a phase I clinical trial for 12 months.

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Therapies Trials Clinical Trials Treatment 188

Drugs.com

JUNE 7, 2023

MONDAY, June 5, 2023 -- An experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds. The oral drug vorasidenib nearly tripled progression-free survival in patients with grade.

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Clinical Trials Drugs Therapies Trials 246

Antidote

JANUARY 3, 2023

Before becoming available to patients, every medication, therapy, and intervention must undergo a rigorous approval process: the clinical trial. Clinical trials are divided into phases that are aimed at testing the safety and efficacy of every potential new treatment before it is able to enter the market.

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Clinical Trials Trials Therapies Treatment 97

Quanticate

SEPTEMBER 25, 2024

In rheumatoid arthritis (RA) clinical trials, accurately measuring the effectiveness of treatments is critical for determining their value in managing this chronic and debilitating condition.

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Clinical Trials Trials Therapies Treatment 97

PPD

NOVEMBER 11, 2024

As a result, biopharma and biotech companies working to bring their drug pipelines to the market require deep expertise from trusted partners to help deliver critical therapies for their patients. Accelerate your drug development and clinical trial goals and benefit from our 360° CDMO and CRO solutions and expertise.

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Drug Development Clinical Trials Drugs Small Molecule 97

BioPharma Drive: Drug Pricing

SEPTEMBER 16, 2024

Applying CAR T-cell therapy in new clinical settings presents unique challenges. Worldwide Clinical Trials is at the forefront, partnering with drug development teams to map this new path forward.

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Therapies Trials Clinical Trials Drug Development 130

PPD

AUGUST 7, 2024

Clinical trials are the backbone of medical research, enabling the development of new treatments and therapies that can improve patient outcomes. However, conducting successful clinical trials requires efficient communication and coordination among various stakeholders.

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Clinical Trials Trials Compliance Clinical Research 97

Drugs.com

JUNE 16, 2023

FRIDAY, June 16, 2023 -- Testosterone replacement therapy is safe for most men with heart problems who also have been diagnosed with a low testosterone disorder, a new clinical trial has concluded. The trial found that testosterone replacement did.

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Therapies Clinical Trials Trials 147

Fierce BioTech

OCTOBER 11, 2023

Discover how incorporating genetic counseling and genetic services can unlock larger, more diverse and better qualified patient populations for your clinical trials. png Listing Introduction Overcome clinical trial recruitment barriers. Click here to login. Listing Image GenomeMedical_ListingLogo_250x190.png

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Clinical Trials Trials Therapies Drugs 95

FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field. In October, FDA announced seven new clinical trial grants awarded in fiscal year (FY) 2024 – including one for a Phase 3 trial – totaling $17.2

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Clinical Development Production Clinical Trials Treatment 69

BioPharma Drive: Drug Pricing

AUGUST 12, 2024

Technology emerging from Yale researcher Craig Crews’ labs will be used to target prostate and breast cancer in early clinical trials.

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Clinical Trials Therapies Trials Research 167