Quanticate

NOVEMBER 21, 2024

An efficacy endpoint in oncology is a characteristic or variable that measures how beneficial a treatment is to a patient’s feeling, function, and survival in a clinical trial. They are essential for assessing whether new cancer therapies are safe and efficacious [1].

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

ProRelix Research

JULY 6, 2023

Biosimilar clinical trials and study designs’ Considerations The rising prevalence and large market share of biological products emphasize their importance as treatment options for several cancers and autoimmune diseases.

Clinical Trials 105

Clinical Trials Biosimilars Trials Treatment 105

ProRelix Research

MAY 31, 2023

Introduction: Clinical trials are a crucial component of the pharmaceutical and medical research industry, aimed at evaluating the safety and effectiveness of new drugs, treatments, or medical devices before they […] The post Successful Clinical Trial With ProRelix Research: Phase 1, 2, 3 & 4 Clinical Trial Services at … appeared (..)

Clinical Trials 98

Clinical Trials Trials Research Pharmaceuticals 98

Quanticate

SEPTEMBER 25, 2024

In rheumatoid arthritis (RA) clinical trials, accurately measuring the effectiveness of treatments is critical for determining their value in managing this chronic and debilitating condition.

Clinical Trials 97

Clinical Trials Trials Therapies Treatment 97

Antidote

JANUARY 3, 2023

Before becoming available to patients, every medication, therapy, and intervention must undergo a rigorous approval process: the clinical trial. Clinical trials are divided into phases that are aimed at testing the safety and efficacy of every potential new treatment before it is able to enter the market.

Clinical Trials 97

Clinical Trials Trials Therapies Treatment 97

Quanticate

SEPTEMBER 13, 2024

With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively.

Clinical Trials 95

Clinical Trials Trials Drug Development Treatment 95

Conversations in Drug Development Trends

MAY 10, 2024

By: Christine Moore, PhD, Vice President, Neuroscience, Scientific Solutions Patients with borderline personality disorder (BPD) face a heightened risk of substance abuse and suicide, as well as substantial delays in receiving treatment.

Clinical Trials 95

Clinical Trials Trials Treatment Drug Development 95

Antidote

DECEMBER 20, 2022

At Antidote, we consider the patient voice in how we think about the entire clinical trial process. From recruitment to randomization, the patient journey is a driving force in all that we do — and we think this strategy is helpful for clinical trial sponsors, as well.

Clinical Trials 98

Clinical Trials Trials Treatment 98

PPD

AUGUST 5, 2024

Though they do positively impact patients’ quality of life and hemodynamic parameters, these treatments — prostacyclin analogs and receptor agonists, phosphodiesterase 5 inhibitors, endothelin-receptor antagonists, and cGMP activators — have shown limited beneficial effects on survival and disease progression.

Clinical Trials 98

Clinical Trials Trials Clinical Research Disease 98

Antidote

AUGUST 21, 2023

Before any new treatment is able to be approved, it is required to go through the vigorous testing process known as clinical trials. These trials are aimed at determining whether or not a drug, medical device, therapy, or other type of intervention is safe and effective for the public.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

Antidote

SEPTEMBER 13, 2023

Globally, there are thousands of research studies and clinical trials conducted each year, all with the shared goal of bringing new treatment options and medical devices to the market. However, approximately 80% of clinical trials are delayed or closed because of problems with recruitment.

Clinical Trials 98

Clinical Trials Trials Treatment Marketing 98

Antidote

AUGUST 29, 2022

In the world of medical research, experts are constantly looking for new drugs, treatments, and therapies for a variety of conditions — but the process of getting these treatments approved is only possible if they are tested through clinical trials.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

Antidote

MAY 22, 2023

Participating in a clinical trial can be a worthwhile opportunity for any individual.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

PPD

OCTOBER 9, 2023

“Patient-centric” is used frequently to describe today’s clinical trial and health care landscape. The industry applauds that point of view and strives to include a patient-centric approach in all aspects of clinical trial designs. Patient centricity has become more than a key consideration.

Clinical Trials 98

Clinical Trials Trials Compliance International 98

Drugs.com

OCTOBER 22, 2024

22, 2024 -- At-home brain stimulation therapy can safely and effectively treat severe to moderate depression, a new clinical trial shows.Rates of treatment response and depression remission were three times higher in people receiving. TUESDAY, Oct.

Treatment 111

Treatment Clinical Trials Therapies Trials 111

Science Daily: Pharmacology News

JUNE 18, 2024

The discovery could lead to more targeted treatments, with fewer side-effects, for issues from lengthy COVID infections to autoimmune diseases like multiple sclerosis. Clinical trials in humans are now planned.

Treatment 135

Treatment Disease Immune Response Clinical Trials 135

ASPET

APRIL 5, 2024

This review provides an overview of recent chemotherapeutics that are in clinical trial, and the combination of drugs that are being investigated to overcome the drug resistance and to improve patient survival in different molecular subtypes of TNBCs.

Treatment 100

Treatment Clinical Trials Trials Drugs 100

Quanticate

DECEMBER 16, 2024

A randomised controlled clinical trial is the most prevalent design used in Phase II and Phase III clinical trials, whereby participants are randomly assigned to a control or experimental group with a fixed probability, normally 50% for each treatment.

Clinical Trials 59

Clinical Trials Trials Disease Treatment 59

Science Daily: Pharmacology News

MARCH 7, 2024

The children, who acquired HIV before birth, were enrolled in a clinical trial in which an ART regimen was started within 48 hours of birth and then closely monitored for drug safety and HIV viral suppression.

Treatment 129

Treatment Clinical Trials Therapies Trials 129

Drug Target Review

JANUARY 15, 2024

Could you provide insights into the driving factors behind exploring novel treatments for cancer types? Could you provide further details on how this phenomenon could impact broader treatment outcomes? What aspects prompted this research direction? The concept of the ‘abscopal effect’ in the 4T1 tumour model is intriguing.

Treatment 105

Treatment Immune Response Therapies Clinical Trials 105

Antidote

FEBRUARY 22, 2024

Behind every new treatment is the incredible team of doctors, researchers, patients, and clinical trial specialists who worked on the research that made it possible.

Clinical Trials 69

Clinical Trials Trials Doctors Therapies 69

SCIENMAG: Medicine & Health

SEPTEMBER 8, 2023

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. Yet, even when drugs demonstrate safety and efficacy in cell and animal models, they frequently encounter hurdles in clinical trials on human. Credit: POSTECH Developing […]

Clinical Trials 84

Clinical Trials Trials Drugs Treatment 84

Drugs.com

SEPTEMBER 4, 2024

4, 2024 -- An experimental three-in-one blood pressure pill works better than layering on meds one at a time, a new clinical trial shows.After a month on the combo pill, 81% of patients had their blood pressure under control. WEDNESDAY, Sept.

Clinical Trials 111

Clinical Trials Treatment Trials 111

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

To find effective treatments and slow the progression of this debilitating disease, researchers have made much progress in developing new drugs that target beta-amyloid plaques, one of […] 7, 2023 – Alzheimer’s disease is the most common cause of dementia that affects more than 6.5

Clinical Trials 84

Clinical Trials Disease Treatment Trials 84

Drugs.com

JUNE 27, 2024

THURSDAY, June 27, 2024 -- Acupuncture can help breast cancer patients deal with the hot flashes that often accompany hormone therapy, a new clinical trial says.Nearly 2 in 3 women who got acupuncture during hormone therapy reported fewer and less.

Clinical Trials 105

Clinical Trials Treatment Therapies Trials 105

SCIENMAG: Medicine & Health

NOVEMBER 27, 2023

An innovative stem cell-based treatment for Type 1 diabetes can meaningfully regulate blood glucose levels and reduce dependence on daily insulin injections, according to new clinical trial results from the University of British Columbia (UBC) and Vancouver Coastal Health (VCH).

Treatment 92

Treatment Clinical Trials Regulations Trials 92

SCIENMAG: Medicine & Health

AUGUST 23, 2023

According to the National Institutes of Health, approximately 24% of adults in the United States have nonalcoholic fatty liver disease (NAFLD), an umbrella term for a range of liver conditions affecting people who drink little to no alcohol that can lead to cirrhosis, liver cancer and liver failure.

Clinical Trials 82

Clinical Trials Treatment Trials Disease 82

FDA Law Blog: Drug Discovery

MARCH 7, 2024

Clissold — The trio of CDER, CBER, and CDRH released a new draft guidance titled “ Use of Data Monitoring Committees in Clinical Trials ” that revises the 2006 guidance “Establishment and Operation of Clinical Trial Data Monitoring Committees” and, when final, will replace the 2006 guidance.

Clinical Trials 105

Clinical Trials Trials FDA Regulations 105

Drug Target Review

MARCH 7, 2024

1 Although pancreatic cancer is rarer than the abovementioned cancers, it claims over 50,000 lives each year in the United States because of a lack of effective treatments. Since then, two therapies have been approved for use in lung and breast cancer but it did not advance pancreatic cancer treatment.

Treatment 98

Treatment Therapies Clinical Trials Research 98

SCIENMAG: Medicine & Health

JUNE 15, 2023

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options. Credit: Vanderbilt University Medical Center A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

Treatment 83

Treatment Clinical Trials Therapies International 83

Drug Target Review

OCTOBER 11, 2023

Most of these conditions are genetic in origin and the majority have no effective treatment. Symptoms were reversed in mouse models and a clinical trial is planned for later this year. That includes countless rare peripheral diseases, including many for which there are currently no treatments.

Disease 113

Disease Treatment Small Molecule Therapies 113

BioPharma Drive: Drug Pricing

JUNE 4, 2024

A group of independent experts wasn't convinced by clinical trial data from company Lykos Therapeutics, which is seeking FDA approval of MDMA-assisted treatment for post-traumatic stress disorder.

FDA 132

FDA FDA Approval Clinical Trials Therapies 132

PLOS: DNA Science

MARCH 28, 2024

FDA classifies it as a “nonsteroidal treatment” – not a gene therapy, but it affects gene expression. The New Drug Duvyzat (givinostat), a type of drug called an HDAC inhibitor, has been in clinical trials to treat cancers and other disorders of the blood, Crohn’s disease, and a form of juvenile arthritis.

FDA Approval 98

FDA Approval Treatment FDA DNA 98

Quanticate

DECEMBER 2, 2024

A defining feature of RCTs is that of randomisation, the statistical process whereby participants are assigned to different treatment groups according to a predefined random mechanism.

Clinical Trials 52

Clinical Trials Trials Treatment 52

SCIENMAG: Medicine & Health

MARCH 28, 2024

LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home. Credit: Ricardo Carrasco III LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at […] (..)

Clinical Trials 87

Clinical Trials Treatment Trials 87

FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.

Clinical Development 69

Clinical Development Production Clinical Trials Treatment 69

ASPET

DECEMBER 22, 2023

These data support further investigation of compounds that can antagonize canonical NF-kB pathway signaling in these cancers and pave the way for clinical trials of PTL in affected dogs. PTL is a promising treatment for histiocytic sarcoma (HS), hemangiosarcoma (HSA), and mast cell neoplasia (MCT).

Clinical Trials 189

Clinical Trials Disease Drugs Therapies 189