ProRelix Research

JULY 6, 2023

Biosimilar clinical trials and study designs’ Considerations The rising prevalence and large market share of biological products emphasize their importance as treatment options for several cancers and autoimmune diseases.

Clinical Trials 105

Clinical Trials Biosimilars Trials Treatment 105

ProRelix Research

MAY 31, 2023

Introduction: Clinical trials are a crucial component of the pharmaceutical and medical research industry, aimed at evaluating the safety and effectiveness of new drugs, treatments, or medical devices before they […] The post Successful Clinical Trial With ProRelix Research: Phase 1, 2, 3 & 4 Clinical Trial Services at … appeared (..)

Clinical Trials 98

Clinical Trials Trials Research Pharmaceuticals 98

ProRelix Research

SEPTEMBER 17, 2023

Since […] The post Ophthalmology disorders and current developments of novel treatments under clinical trials appeared first on ProRelix Research.

Clinical Trials 98

Clinical Trials Trials Treatment Disease 98

Quanticate

SEPTEMBER 25, 2024

In rheumatoid arthritis (RA) clinical trials, accurately measuring the effectiveness of treatments is critical for determining their value in managing this chronic and debilitating condition.

Clinical Trials 97

Clinical Trials Trials Therapies Treatment 97

Quanticate

SEPTEMBER 13, 2024

With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively.

Clinical Trials 95

Clinical Trials Trials Drug Development Treatment 95

Antidote

JANUARY 3, 2023

Before becoming available to patients, every medication, therapy, and intervention must undergo a rigorous approval process: the clinical trial. Clinical trials are divided into phases that are aimed at testing the safety and efficacy of every potential new treatment before it is able to enter the market.

Clinical Trials 97

Clinical Trials Trials Therapies Treatment 97

Conversations in Drug Development Trends

MAY 10, 2024

By: Christine Moore, PhD, Vice President, Neuroscience, Scientific Solutions Patients with borderline personality disorder (BPD) face a heightened risk of substance abuse and suicide, as well as substantial delays in receiving treatment.

Clinical Trials 95

Clinical Trials Trials Treatment Drug Development 95

Antidote

DECEMBER 20, 2022

At Antidote, we consider the patient voice in how we think about the entire clinical trial process. From recruitment to randomization, the patient journey is a driving force in all that we do — and we think this strategy is helpful for clinical trial sponsors, as well.

Clinical Trials 98

Clinical Trials Trials Treatment 98

PPD

AUGUST 5, 2024

Though they do positively impact patients’ quality of life and hemodynamic parameters, these treatments — prostacyclin analogs and receptor agonists, phosphodiesterase 5 inhibitors, endothelin-receptor antagonists, and cGMP activators — have shown limited beneficial effects on survival and disease progression.

Clinical Trials 98

Clinical Trials Trials Clinical Research Disease 98

Antidote

AUGUST 21, 2023

Before any new treatment is able to be approved, it is required to go through the vigorous testing process known as clinical trials. These trials are aimed at determining whether or not a drug, medical device, therapy, or other type of intervention is safe and effective for the public.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

Antidote

SEPTEMBER 13, 2023

Globally, there are thousands of research studies and clinical trials conducted each year, all with the shared goal of bringing new treatment options and medical devices to the market. However, approximately 80% of clinical trials are delayed or closed because of problems with recruitment.

Clinical Trials 98

Clinical Trials Trials Treatment Marketing 98

Antidote

AUGUST 29, 2022

In the world of medical research, experts are constantly looking for new drugs, treatments, and therapies for a variety of conditions — but the process of getting these treatments approved is only possible if they are tested through clinical trials.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

PPD

OCTOBER 9, 2023

“Patient-centric” is used frequently to describe today’s clinical trial and health care landscape. The industry applauds that point of view and strives to include a patient-centric approach in all aspects of clinical trial designs. Patient centricity has become more than a key consideration.

Clinical Trials 98

Clinical Trials Trials Compliance International 98

Antidote

MAY 22, 2023

Participating in a clinical trial can be a worthwhile opportunity for any individual.

Clinical Trials 98

Clinical Trials Trials Therapies Treatment 98

Quanticate

DECEMBER 16, 2024

A randomised controlled clinical trial is the most prevalent design used in Phase II and Phase III clinical trials, whereby participants are randomly assigned to a control or experimental group with a fixed probability, normally 50% for each treatment.

Clinical Trials 59

Clinical Trials Trials Disease Treatment 59

Drugs.com

OCTOBER 22, 2024

22, 2024 -- At-home brain stimulation therapy can safely and effectively treat severe to moderate depression, a new clinical trial shows.Rates of treatment response and depression remission were three times higher in people receiving. TUESDAY, Oct.

Treatment 111

Treatment Clinical Trials Therapies Trials 111

Science Daily: Pharmacology News

JUNE 18, 2024

The discovery could lead to more targeted treatments, with fewer side-effects, for issues from lengthy COVID infections to autoimmune diseases like multiple sclerosis. Clinical trials in humans are now planned.

Treatment 135

Treatment Disease Immune Response Clinical Trials 135

FDA Law Blog: Drug Discovery

MARCH 7, 2024

Clissold — The trio of CDER, CBER, and CDRH released a new draft guidance titled “ Use of Data Monitoring Committees in Clinical Trials ” that revises the 2006 guidance “Establishment and Operation of Clinical Trial Data Monitoring Committees” and, when final, will replace the 2006 guidance.

Clinical Trials 105

Clinical Trials Trials FDA Regulations 105

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows. THURSDAY, Sept. People with hemophilia B saw their bleeding episodes.

Therapies 116

Therapies Trials Clinical Trials Treatment 116

Antidote

FEBRUARY 22, 2024

Behind every new treatment is the incredible team of doctors, researchers, patients, and clinical trial specialists who worked on the research that made it possible.

Clinical Trials 69

Clinical Trials Trials Doctors Therapies 69

SCIENMAG: Medicine & Health

SEPTEMBER 8, 2023

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. Yet, even when drugs demonstrate safety and efficacy in cell and animal models, they frequently encounter hurdles in clinical trials on human. Credit: POSTECH Developing […]

Clinical Trials 84

Clinical Trials Trials Drugs Treatment 84

ASPET

APRIL 5, 2024

This review provides an overview of recent chemotherapeutics that are in clinical trial, and the combination of drugs that are being investigated to overcome the drug resistance and to improve patient survival in different molecular subtypes of TNBCs.

Treatment 100

Treatment Clinical Trials Trials Drugs 100

Science Daily: Pharmacology News

MARCH 7, 2024

The children, who acquired HIV before birth, were enrolled in a clinical trial in which an ART regimen was started within 48 hours of birth and then closely monitored for drug safety and HIV viral suppression.

Treatment 129

Treatment Clinical Trials Therapies Trials 129

Quanticate

DECEMBER 2, 2024

Double-blind randomised controlled trials (RCTs) are the gold standard for evaluating clinical interventions in the biomedical field. A defining feature of RCTs is that of randomisation, the statistical process whereby participants are assigned to different treatment groups according to a predefined random mechanism.

Clinical Trials 52

Clinical Trials Trials Treatment 52

Drugs.com

SEPTEMBER 26, 2024

25, 2024 -- A new gene therapy approved earlier this year can serve as a sustainable single-dose treatment for people with hemophilia B, newly published clinical trial data shows.People with hemophilia B saw their bleeding episodes. THURSDAY, Sept.

Therapies 98

Therapies Trials Clinical Trials Treatment 98

SCIENMAG: Medicine & Health

AUGUST 23, 2023

According to the National Institutes of Health, approximately 24% of adults in the United States have nonalcoholic fatty liver disease (NAFLD), an umbrella term for a range of liver conditions affecting people who drink little to no alcohol that can lead to cirrhosis, liver cancer and liver failure.

Clinical Trials 82

Clinical Trials Treatment Trials Disease 82

SCIENMAG: Medicine & Health

SEPTEMBER 7, 2023

To find effective treatments and slow the progression of this debilitating disease, researchers have made much progress in developing new drugs that target beta-amyloid plaques, one of […] 7, 2023 – Alzheimer’s disease is the most common cause of dementia that affects more than 6.5

Clinical Trials 84

Clinical Trials Disease Treatment Trials 84

PPD

JUNE 7, 2023

As therapies for the treatment of NASH in adult patients go this year to the U.S. Food and Drug Administration (FDA) for approval , much work remains for drug developers aiming to advance treatments for pediatric populations. Partnership with an experienced CRO is essential to your trial’s success. Hispanic: 11.8%

Trials 98

Trials Clinical Trials Clinical Research Disease 98

Drugs.com

SEPTEMBER 4, 2024

4, 2024 -- An experimental three-in-one blood pressure pill works better than layering on meds one at a time, a new clinical trial shows.After a month on the combo pill, 81% of patients had their blood pressure under control. WEDNESDAY, Sept.

Clinical Trials 111

Clinical Trials Treatment Trials 111

Perficient: Drug Development

SEPTEMBER 25, 2024

Clinical trial data management is critical to pharmaceutical research, yet it remains a significant challenge for many organizations. Outdated systems: Many organizations rely on legacy data management tools that fail to meet the demands of modern clinical trials.

Clinical Trials 52

Clinical Trials Trials Science Production 52

BioPharma Drive: Drug Pricing

JUNE 4, 2024

A group of independent experts wasn't convinced by clinical trial data from company Lykos Therapeutics, which is seeking FDA approval of MDMA-assisted treatment for post-traumatic stress disorder.

FDA 132

FDA FDA Approval Clinical Trials Therapies 132

Conversations in Drug Development Trends

JANUARY 24, 2024

Written By: Derek Ansel, MS, CCRA, Executive Director, Therapeutic Strategy Lead, Rare Disease Given that 80% of rare diseases have a genetic etiology, genetic implications should be addressed at the onset of a clinical program to support trial enrollment. One diagnostic example that I discussed in my presentation is autism.

Trials 75

Trials Disease Clinical Trials Clinical Research 75

Drug Target Review

JANUARY 15, 2024

Could you provide insights into the driving factors behind exploring novel treatments for cancer types? Based on this rationale we selected skin cancer, triple-negative breast cancer, and head and neck cancers as our initial indications for our Phase 1 trials. What aspects prompted this research direction?

Treatment 105

Treatment Immune Response Therapies Clinical Trials 105

Drugs.com

JUNE 27, 2024

THURSDAY, June 27, 2024 -- Acupuncture can help breast cancer patients deal with the hot flashes that often accompany hormone therapy, a new clinical trial says.Nearly 2 in 3 women who got acupuncture during hormone therapy reported fewer and less.

Clinical Trials 105

Clinical Trials Treatment Therapies Trials 105

PPD

JUNE 24, 2024

In the realm of vaccine development, mega trials — studies enrolling 5,000 subjects or more — have been instrumental in the fight against many pathogens, including influenza, rotavirus, malaria, RSV and most recently in the rapid development of vaccines against COVID-19.

Vaccine 97

Vaccine Trials Clinical Trials Laboratories 97

Advarra

OCTOBER 1, 2024

Managing clinical trial budgets efficiently is necessary for the success and sustainability of clinical research sites. Effective budget management not only ensures trials are financially viable but also maximizes return on investment (ROI). the impact and value of the data produced).

Clinical Trials 52

Clinical Trials Trials Compliance Laboratories 52

ProRelix Research

NOVEMBER 5, 2024

Clinical trials are necessary in advancing medical research and health care options by allowing new treatments to be introduced in the market through safety and efficacy testing in humans. Successful […] The post Clinical Trials and Human Subject Protection as per US FDA appeared first on ProRelix Research.

Clinical Trials 52

Clinical Trials FDA Trials Treatment 52