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How Can High Content Imaging Transform Your Cancer Research?

Crown Bioscience

Designed for high-throughput applications, HCI accelerates therapeutic compound screening while uncovering mechanisms of resistance and drug responses.

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ChEMBL 34 is out!

The ChEMBL-og

We are delighted to announce the release of ChEMBL 34, which includes a full update to drug and clinical candidate drug data. 71 out of the 882 newly added EMA drugs are only authorised by EMA, rather than from other regulatory bodies e.g. FDA. This data is currently available for European Medicines Agency drugs only.

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Sygnature Discovery completes acquisition of SB Drug Discovery to further strengthen its market-leading capabilities

Sygnature Discovery

Sygnature Discovery (“Sygnature”) is delighted to announce the acquisition of SB Drug Discovery, a world leading provider of ion channel and receptor drug discovery research delivering cell line generation and compound screening solutions in neuroscience and other therapeutic indications.

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Protein Science & Structural Biology

Sygnature Discovery

Compound Screening Fragment Based Drug Discovery supported by Crystallography or SPR & MST. Covalent compound binding by mass spectrometry. Protein Characterisation & Quality Control Mass spectrometry – intact protein, peptide mapping and native. NMR, FIDA, ITC, SEC-MALS and FSEC.

Science 52
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Target-directed cancer: protein-ligand interactions  

Drug Target Review

Could you provide an overview of your research on target directed cancer drug discovery, particularly your focus on protein lagging interactions. I work in the Centre for Cancer Drug Discovery (CCDD) at The Institute of Cancer Research in London, which is an academic drug discovery centre. 2013) 56, 2059-2073.

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Compound Management

Sygnature Discovery

Accelerate the entire drug discovery process with increased accuracy and tracking with our state-of-the-art compound management facility. Compound management is central to the drug discovery workflow, encompassing the logistics, storage, tracking, dispensing, and preparation of compounds for testing and analysis.

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[Panel Webinar] How to tap into pharma’s $100bn digital transformation opportunity

The Pharma Data

Next-generation digital technologies are having an immense impact on the drug discovery process. The pharma industry is witnessing a steep rise in the use of AI-driven solutions in early-stage drug discovery, deep-learning technologies for compound screening, and lead identification and automation enhancements in the lab.