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We are delighted to announce the release of ChEMBL 34, which includes a full update to drug and clinical candidate drug data. 71 out of the 882 newly added EMA drugs are only authorised by EMA, rather than from other regulatory bodies e.g. FDA. This data is currently available for European Medicines Agency drugs only.
Sygnature Discovery (“Sygnature”) is delighted to announce the acquisition of SB Drug Discovery, a world leading provider of ion channel and receptor drug discovery research delivering cell line generation and compoundscreening solutions in neuroscience and other therapeutic indications.
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Could you provide an overview of your research on target directed cancer drug discovery, particularly your focus on protein lagging interactions. I work in the Centre for Cancer Drug Discovery (CCDD) at The Institute of Cancer Research in London, which is an academic drug discovery centre. 2013) 56, 2059-2073.
Accelerate the entire drug discovery process with increased accuracy and tracking with our state-of-the-art compound management facility. Compound management is central to the drug discovery workflow, encompassing the logistics, storage, tracking, dispensing, and preparation of compounds for testing and analysis.
Next-generation digital technologies are having an immense impact on the drug discovery process. The pharma industry is witnessing a steep rise in the use of AI-driven solutions in early-stage drug discovery, deep-learning technologies for compoundscreening, and lead identification and automation enhancements in the lab.
Learn more Drug Repurposing Hub A curated and annotated collection of FDA-approved drugs, clinical trial drugs, and pre-clinical tool compounds. Learn more PRISM Rapid, high-throughput multiplexed compoundscreening in genomically characterized human cancer cell-line models.
We also extend our deepest gratitude to n-Lorem for creating and providing the ASO drug that made this trial possible. ” While the primary focus of CIRM grants has been cell therapy, it has also promoted the use of cell-based disease modeling and compoundscreening, as well as the development of gene-based therapies.
Marto SLAS Discovery, 2024 [link] Target-based screening of covalent fragment libraries with mass spectrometry has emerged as a powerful strategy to identify chemical starting points for small molecule inhibitors or find new binding pockets on proteins of interest. These libraries span diverse chemical space with a modest number of compounds.
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