Remove Computational Chemistry Remove Disease Remove Pharmaceutical Companies
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Lead Pharma enters into a Research Collaboration and License Agreement with Roche to Develop Oral Small Molecules for Immune Mediated Diseases

The Pharma Data

” Arthur Oubrie, Chief Scientific Officer of Lead Pharma, added: “This is the second project we partner with one of the largest pharmaceutical companies under our Discover, Design and Deliver platform. ” About Immune Mediated Diseases. A wide range of human diseases is driven by deregulated immune function.

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The Data-Driven Future of Drug Development

DrugBank

By harnessing the vast amounts of data generated throughout the development pipeline, pharmaceutical companies can accelerate the discovery of novel therapies, optimize clinical trial design, enhance drug safety monitoring, and deliver personalized medicine, ultimately improving patient outcomes and transforming the future of healthcare.

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Drug Repurposing: A New Life for Old Drugs

DrugBank

Opportunities in Drug Repurposing There is great potential for drug repurposing to unlock treatments for rare and neglected diseases, where traditional drug development is too costly. Pharma companies are often rich with valuable chemical libraries and expertise, while academics bring emerging disease biology knowledge.

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Sygnature Discovery deploys Iktos’ AI technology ‘Makya™’

Sygnature Discovery

They have established multiple collaborations with renowned pharmaceutical companies and successfully developed the AI software platforms Makya™ for new drug design and Spaya™ for synthesis planning.

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Some Thoughts on Biotech vs Pharma for Computational Chemists

Practical Cheminformatics

A recent editorial by Dean Brown in J Med Chem and follow-up posts by Keith Hornberger and Derek Lowe prompted me to think about how we train computational chemists and cheminformaticians for careers in drug discovery. It also brought to mind some unique differences between how computational chemistry is practiced in biotech and pharma.

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The Book of Nimbus

LifeSciVC

The premise at the time was that putting computational chemistry in the primary position for new molecule ideation would upend the drug discovery paradigm. set up a “virtual project team,” leverage Schrödinger scientists to lead computational chemistry, and do all the wet work at CROs. It did just that.

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Sygnature Discovery accelerates global growth with major North American acquisition

Sygnature Discovery

Founded in 2011, NuChem Sciences delivers expert integrated and standalone discovery solutions across medicinal, synthetic, scale-up, process and computational chemistry, as well as DMPK, in vitro biology and in vivo pharmacology.