Practical Cheminformatics

JANUARY 16, 2024

Following up on Part I and Part II, the third post in this series is a collection of review articles published in 2023 that I found helpful.

Targeted Protein Degradation 141

Targeted Protein Degradation Small Molecule Computational Chemistry Bioinformatics 141

Drug Discovery World

SEPTEMBER 6, 2023

BioPharmics’ CEO, Dr Ajay Jain, and Director of Applied Science, Dr Ann Cleves, will join the Optibrium team, respectively focusing on R&D and Application Science in the newly-created BioPharmics Division. AI drug discovery company Optibrium has acquired 3D drug design specialist BioPharmics.

Small Molecule 130

Small Molecule Science Computational Chemistry Drugs 130

Sygnature Discovery

APRIL 18, 2023

Sygnature Discovery is pleased to have entered into a research collaboration agreement with the global healthcare group Daewoong Pharmaceutical to accelerate the discovery of a novel small molecule to target autoimmune disease.

Small Molecule 52

Small Molecule Computational Chemistry Research Science 52

Drug Target Review

NOVEMBER 1, 2023

The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinical trials. For example, in the screening stage of a project we are trying to find initial starting points for optimisation by our medicinal and computational chemistry colleagues.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

Drug Discovery World

SEPTEMBER 9, 2024

The transformative power of AI While Foundation Models (FMs), including Large Language Models (LLMs) and image-based models, may not exhibit true intelligence, their potential to revolutionise fields like drug discovery and materials science is undeniable. Small Language Models (SLMs) are gaining traction, particularly in the life sciences.

Drugs 162

Drugs Bioinformatics Computational Chemistry International 162

Drug Target Review

MAY 31, 2024

Working at the intersection of medicinal and computational chemistry as an early adopter of integrating in silico tools into the discovery process, I’ve seen first hand the technological advances that have been made over the past five-plus years. She is an active voice for diversity and inclusion in the Sciences.

Organic Chemistry 45

Organic Chemistry Computational Chemistry Small Molecule Disease 45

The Pharma Data

NOVEMBER 15, 2020

R&D collaboration building on Lead Pharma’s expertise in the discovery, design and optimization of small molecule treatments. Our rigorous target selection process, translational screening cascade, and smart medicinal chemistry have been essential to bring this project to this stage.

Small Molecule 52

Small Molecule Licensing Licensing Disease 52