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#WhyIScience Q&A: A process development lead returns to her research roots

Broad Institute

By Andrea Tamayo May 30, 2023 Credit: Allison Dougherty, Broad Communications Isabella Teixeira-Soldano studies single cells to better understand disease progression. After graduating, Teixeira-Soldano discovered new definitions of development that intrigued her. When I went to school, I was set on becoming a doctor.

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How AI is accelerating the future of precision medicine

Drug Target Review

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Biomarker information is also useful for tracking progression of the disease and treatment response. Most drugs do not work in all people.

Doctors 111
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To help his daughter living with an ultra-rare disorder, this dad brought together a squad of genetic detectives

Broad Institute

They knew that discovering the genetic cause of her disorder would help them find other people like her, help get the condition formally recognized as a new disease, and help them better advocate for research into new treatments. This is the first human disease caused by loss of one copy of a lncRNA gene.

DNA 128
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On Fables and Nuanced Charts

Codon

Before 1994, the International Classification of Diseases (ICD) defined a “maternal death” as one where pregnancy is listed as the underlying cause of death on the death certificate. ” The ICD also recommended “pregnancy checkboxes” on death certificates to help doctors catch more pregnancy-related deaths.

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#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Broad Institute

If we can understand how those processes work, we can better develop drugs to target these multifaceted diseases. With rapid autopsies, you can look at a cancer’s life and see how it developed from a primary to metastatic disease. I’m definitely proud of the papers I’ve been on and the work I’ve done in Gaddy’s group.

Science 124
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Advances in personalised medicine, leave data processing behind

Drug Target Review

Tailoring medical care to a patient’s unique genetic makeup, alongside the close analysis of disease progression, leads to more effective treatments, reduced side effects and faster diagnoses. It involves, almost by definition, the consolidation of extensive patient data: genomic information, health records and other external resources.

Treatment 105
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FDA Grants Priority Review to Genentech’s Esbriet (pirfenidone) for Unclassifiable Interstitial Lung Disease

The Pharma Data

Food and Drug Administration (FDA) has accepted the company’s supplemental New Drug Application (sNDA) and granted Priority Review for Esbriet ® (pirfenidone) for the treatment of unclassifiable interstitial lung disease (UILD). About Unclassifiable Interstitial Lung Disease. Since its U.S. About the Pivotal Study. Indication.

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