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Pfizer and BioNTech to Potentially Supply the EU with 200 Million Doses of mRNA-based Vaccine Candidate Against SARS-CoV-2

The Pharma Data

The vaccine supply for the EU would be produced by BioNTech’s manufacturing sites in Germany and Pfizer’s manufacturing site in Belgium. The proposed supply agreement with the European Commission would represent the largest initial order of vaccine doses for Pfizer and BioNTech to date. billion doses by the end of 2021.

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Analysis Chemical Thank You PFOA and PFOS designated as hazardous substances under Superfund

Agency IQ

However, other groups, like the Organisation for Economic Co-operation and Development (OECD), have also issued their own definitions for PFAS. These dangers included several adverse human health effects, such as high cholesterol, changes in liver enzymes, decreased immune response to vaccination, thyroid disorders, and cancer.

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Article FDA Thank You FDA updates guidance on developing drugs for Covid-19, replacing pandemic-era version

Agency IQ

The FDA also implemented new flexibilities for certain regulated products and processes, typically via enforcement discretion. It also stated that companies should consider whether an investigational product might interact with an administered vaccine for Covid-19.

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Analysis Chemical Thank You Senate hearing on hazardous substance listing for PFAS finds common ground, but disagreements on implementation tactics

Agency IQ

How the agency plans to regulate PFAS via CERCLA In late 2021, the EPA published the PFAS Strategic Roadmap , which laid out the planned PFAS strategy for the agency between 2021 and 2024. high cholesterol, changes in liver enzymes, decreased immune response to vaccination, thyroid disorders, and cancer).

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Statement of the Twenty-Sixth Polio IHR Emergency Committee

The Pharma Data

The twenty-sixth meeting of the Emergency Committee under the International Health Regulations (2005) (IHR) on the international spread of poliovirus was convened and opened by the WHO Deputy Director-General on 14 October 2020 with committee members attending via video conference, supported by the WHO Secretariat.

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World RNA Day: What impact RNA it had on drug discovery?  

Drug Discovery World

As per a definition provided by AstraZeneca: “Once inside, ASOs bind with high specificity to target mRNA or pre-mRNA, inducing its degradation – effectively silencing it – to prevent its translation into a detrimental protein product. Harwell, a science and innovation campus in Oxfordshire, was selected for the location.

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Novartis to present broad range of portfolio data at ECTRIMS, reinforcing long-standing commitment to people living with multiple sclerosis

The Pharma Data

years of exposure 3 Design of a new open-label study assessing immune response to SARS-CoV-2 mRNA vaccines in MS-patients treated with Kesimpta 4 , and new findings from open-label study assessing immune response to SARS-CoV-2 mRNA vaccines in secondary progressive MS (SPMS) patients treated with Mayzent will be presented 5.