Definition, Therapies, Vaccine and Virus

Where is the Ignite Theater tech leading us?

Drug Discovery World

JANUARY 22, 2024

It states: ” An integrated appreciation of the physiological consequences of DUB modulation in relevant cancer models will eventually lead to the identification of patient populations that will most likely benefit from DUB-targeted therapies” 1.

Immune Response

Immune Response Vaccine Engineering Virus

AstraZeneca’s COVID-19 Vaccine Boasts Strong Results with Up to 90% Efficacy

The Pharma Data

NOVEMBER 22, 2020

As the Pfizer and BioNTech COVID-19 vaccine goes to regulators and the Moderna vaccine approaches the end of its Phase III trials, AstraZeneca and the University of Oxford announced high-level results from an interim analysis of their COVID-19 vaccine, AZD1222. The combined analysis showed average efficacy of 70%.

Vaccine

Vaccine Virus Trials Regulations

Science community calls for transparency on AstraZeneca's halted US COVID-19 vaccine trial

The Pharma Data

SEPTEMBER 23, 2020

The halting of AstraZeneca’s COVID-19 vaccine trial around the world was cause for much initial concern over the eventual safety and efficacy of the therapy. Eventually, it’s the public who will either take this vaccine or not, so it is to their advantage to be transparent as possible.”. Matt Fellows. Source link.

Vaccine

Vaccine Trials Science Regulations

ImmunityBio’s hAd5 T-Cell COVID-19 Vaccine Candidate Shows Complete Protection of Airways in Non-Human Primates

The Pharma Data

DECEMBER 10, 2020

–( BUSINESS WIRE )– ImmunityBio , a privately-held immunotherapy company, today announced its COVID-19 vaccine candidate protected nasal and lung airways of non-human primates against coronavirus (SARS-CoV-2) in a challenge study. 11, 2020 02:48 UTC. CULVER CITY, Calif.–( This press release features multimedia.

Vaccine

Vaccine Immune Response Virus Clinical Trials

FIRST AUTHORIZATION IN EUROPEAN UNION FOR COVID-19 VACCINE IN ADOLESCENTS

The Pharma Data

JUNE 24, 2021

This follows the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) positive opinion to authorize the vaccine in this age group. COMIRNATY was the first COVID-19 vaccine to receive authorization in the EU and is the first to have its CMA extended to adolescents. g doses of the COVID-19 vaccine.

Vaccine

Vaccine Clinical Trials FDA Trials

Pfizer and BioNTech to Potentially Supply the EU with 200 Million Doses of mRNA-based Vaccine Candidate Against SARS-CoV-2

The Pharma Data

SEPTEMBER 9, 2020

The vaccine supply for the EU would be produced by BioNTech’s manufacturing sites in Germany and Pfizer’s manufacturing site in Belgium. The proposed supply agreement with the European Commission would represent the largest initial order of vaccine doses for Pfizer and BioNTech to date. billion doses by the end of 2021.

Vaccine

Vaccine Clinical Trials Trials Government

Analysis Life Sciences Thank You The U.S. regulatory landscape for probiotics and other microbiome-based therapies

Agency IQ

NOVEMBER 3, 2023

regulatory landscape for probiotics and other microbiome-based therapies Probiotics, a type of microbiome-based therapy containing live micro-organisms, are broadly available on drug store and grocery store shelves, but the regulatory classifications for products containing the same micro-organism can differ dramatically.

Therapies

Therapies Science FDA Production

FDA Authorizes Phase 1 Trial of ImmunityBio’s Novel COVID-19 Vaccine Candidate hAd5; Dual Construct is Designed to Drive Both T Cell and Antibody Immunity

The Pharma Data

OCTOBER 14, 2020

Food and Drug Administration (FDA) to begin a Phase I clinical trial of hAd5-COVID-19, the company’s novel COVID-19 vaccine candidate that targets both the inner nucleocapsid (N), engineered to activate T cells, and outer spike (S) protein, engineered to activate antibodies against the coronavirus (SARS-CoV-2).

Vaccine

Vaccine Trials FDA Clinical Trials

Cell and gene therapy – where is the innovation?

Drug Discovery World

SEPTEMBER 16, 2022

Here, DDW Editor Reece Armstrong explores the global hubs of innovation for cell and gene therapies. Since the approval of Kymirah in 2017, the cell and gene therapy sector has emerged as an exciting and innovative market, representing some of the most promising drugs the pharmaceutical industry has ever seen. .

Therapies

Therapies Clinical Trials Production Trials

Regeneron Announces U.S. Government Agreement to Purchase Additional COVID-19 Antibody Cocktail Doses

The Pharma Data

JANUARY 12, 2021

“Tackling the COVID-19 pandemic will require a combination of public health measures, vaccines and therapeutics. “Additionally, as expected, the virus continues to mutate, with the possibility of developing resistance to any one antibody. . Schleifer , M.D., President and Chief Executive Officer of Regeneron. In the U.S.

Government

Government Hospitals Virus Production

The role of RNA in immunotherapies

Drug Discovery World

MAY 23, 2024

SD: The ability of RNA therapies to use the body’s own mechanisms to reprogram cells and tissues towards a healthy state offer a transformative approach to medicine, with early applications in the immunotherapy space. RA: Are multi-mechanistic or combination immunotherapies therapies better at fighting cancerous tumours?

RNA

RNA Therapies Engineering Disease

Pfizer to Acquire ReViral and Its Respiratory Syncytial Virus Therapeutic Candidates

The Pharma Data

APRIL 7, 2022

announced today that the companies have entered into a definitive agreement under which Pfizer will acquire ReViral, a privately held, clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing novel antiviral therapeutics that target respiratory syncytial virus (RSV). NYSE: PFE) and ReViral Ltd.

Virus

Virus Vaccine Clinical Development Hospitals

Analysis Life Sciences Thank You Revised ICH viral safety guideline: NGS is in, animal use (mostly) out

Agency IQ

JANUARY 19, 2024

Though some biological products may be developed using PCCs, such as viral vaccines, these cultures are also commonly used for in vitro experiments that seek to mimic in vivo conditions as closely as possible (e.g., for renal function studies ). Secondly, their use minimizes both the risk and the impact of viral contamination.

Science

Science Virus Production FDA

Regeneron’s Casirivimab and Imdevimab Antibody Cocktail for COVID-19 is First Combination Therapy to Receive FDA Emergency Use Authorization

The Pharma Data

NOVEMBER 20, 2020

NASDAQ: REGN) today announced that the antibody cocktail casirivimab and imdevimab administered together (formerly known as REGN-COV2 or REGEN-COV2), a therapy currently being investigated for use in COVID-19 , has received Emergency Use Authorization (EUA) from the U.S. TARRYTOWN, N.Y., November 21, 2020 – Regeneron Pharmaceuticals, Inc.

Therapies

Therapies FDA Clinical Trials Hospitals

World RNA Day: What impact RNA it had on drug discovery?

Drug Discovery World

AUGUST 1, 2023

As per a definition provided by AstraZeneca: “Once inside, ASOs bind with high specificity to target mRNA or pre-mRNA, inducing its degradation – effectively silencing it – to prevent its translation into a detrimental protein product.

RNA

RNA Vaccine Drugs Disease

Why I’m Not Worried that ChatGPT Will Replace Me as a Biology Textbook Author

PLOS: DNA Science

SEPTEMBER 7, 2023

I could imagine it spitting out definitions, but a textbook is much more than “content.” It earns an A+ in returning definitions of obscure technical terms, like tetrachromacy (enhanced color vision from a fourth type of cone cell) and chromothripsis (shattered chromosomes). ” That definition covers all bases.

DNA

DNA Science Therapies Licensing

Sanofi continued its growth trajectory. Strong increase in Q1 2021 business EPS(1) at CER

The Pharma Data

APRIL 27, 2021

at CER driven by growth drivers Dupixent ® and Vaccines. Vaccines up 5.3%, driven by PPH franchise and demand for influenza vaccines in southern hemisphere. Vaccines delivered growth in its core segments. Business net income is a non-GAAP financial measure (definition in Appendix 7). Q1 2021 sales increase of 2.4%

Vaccine

Vaccine Production FDA FDA Approval

Regeneron’s REGEN-COV2 is First Antibody Cocktail for COVID-19 to Receive FDA Emergency Use Authorization

The Pharma Data

NOVEMBER 21, 2020

NASDAQ: REGN) today announced that the antibody cocktail casirivimab and imdevimab administered together (also known as REGN-COV2 or REGEN-COV2), a therapy currently being investigated for use in COVID-19, has received Emergency Use Authorization (EUA) from the U.S. Regeneron Pharmaceuticals, Inc. Food and Drug Administration (FDA).

FDA

FDA Clinical Trials Hospitals Government

Update on AZD7442 STORM CHASER trial in post-exposure prevention of symptomatic COVID-19

The Pharma Data

JUNE 25, 2021

AstraZeneca today announced results from the STORM CHASER trial assessing the safety and efficacy of AZD7442, a long-acting antibody (LAAB) combination, for the prevention of symptomatic COVID-19 in participants recently exposed to the SARS-CoV-2 virus. The PROVENT trial will give us more clarity in this patient population.

Trials

Trials Long-Term Care Facilities Virus Government

Codon: Notes on Progress #2

Codon

MARCH 12, 2023

Base editor proteins were delivered into the mice using a virus, called AAV9. Related news : “More than 200 people have been treated with experimental CRISPR therapies.” coli genes into a piece of simian virus DNA. Lots of gene therapy data this week. ” Nature Medicine ( 1 and 2 ) 4 of 31.

DNA

DNA Engineering RNA Therapies

US allows emergency use of blood plasma treatment for coronavirus patients

The Pharma Data

AUGUST 24, 2020

“I’m pleased to make a truly historic announcement in our battle against the China virus that will save countless lives.” ” Mr Trump described the procedure as a powerful therapy, as he appealed to Americans to come forward to donate plasma if they had recovered from Covid-19. Balance of risks.

Treatment

Treatment FDA Vaccine Virus

Drug Discovery Digest

Where is the Ignite Theater tech leading us?

AstraZeneca’s COVID-19 Vaccine Boasts Strong Results with Up to 90% Efficacy

Trending Sources

Science community calls for transparency on AstraZeneca's halted US COVID-19 vaccine trial

ImmunityBio’s hAd5 T-Cell COVID-19 Vaccine Candidate Shows Complete Protection of Airways in Non-Human Primates

FIRST AUTHORIZATION IN EUROPEAN UNION FOR COVID-19 VACCINE IN ADOLESCENTS

Pfizer and BioNTech to Potentially Supply the EU with 200 Million Doses of mRNA-based Vaccine Candidate Against SARS-CoV-2

Analysis Life Sciences Thank You The U.S. regulatory landscape for probiotics and other microbiome-based therapies

FDA Authorizes Phase 1 Trial of ImmunityBio’s Novel COVID-19 Vaccine Candidate hAd5; Dual Construct is Designed to Drive Both T Cell and Antibody Immunity

Cell and gene therapy – where is the innovation?

Regeneron Announces U.S. Government Agreement to Purchase Additional COVID-19 Antibody Cocktail Doses

The role of RNA in immunotherapies

Pfizer to Acquire ReViral and Its Respiratory Syncytial Virus Therapeutic Candidates

Analysis Life Sciences Thank You Revised ICH viral safety guideline: NGS is in, animal use (mostly) out

Regeneron’s Casirivimab and Imdevimab Antibody Cocktail for COVID-19 is First Combination Therapy to Receive FDA Emergency Use Authorization

World RNA Day: What impact RNA it had on drug discovery?

Why I’m Not Worried that ChatGPT Will Replace Me as a Biology Textbook Author

Sanofi continued its growth trajectory. Strong increase in Q1 2021 business EPS(1) at CER

Regeneron’s REGEN-COV2 is First Antibody Cocktail for COVID-19 to Receive FDA Emergency Use Authorization

Update on AZD7442 STORM CHASER trial in post-exposure prevention of symptomatic COVID-19

Codon: Notes on Progress #2

US allows emergency use of blood plasma treatment for coronavirus patients

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