Practical Cheminformatics

JANUARY 8, 2024

Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce. The authors provided examples where GPT-4 could provide a SMILES string, IUPAC name, or descriptive text for a marketed drug. Most of the drug discovery examples were underwhelming.

Drugs 139

Drugs Small Molecule Bioinformatics Packaging 139

Codon

MAY 30, 2023

Read Programming inactive RNA-binding small molecules into bioactive degraders. He took products to market at prices people were willing to pay. The demos are this Sunday, June 4th! Molecular Therapy. Read Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies. Nature Communications.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

Read Programming inactive RNA-binding small molecules into bioactive degraders. He took products to market at prices people were willing to pay. The demos are this Sunday, June 4th! Molecular Therapy. Read Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies. Nature Communications.

DNA 52

DNA RNA Engineering Vaccine 52