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AI in Drug Discovery - A Highly Opinionated Literature Review (Part II)

Practical Cheminformatics

Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce. This version augments the denovo design capabilities of the previous versions with new R-group replacement and molecule-linking capabilities.

Drugs 141
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read Programming inactive RNA-binding small molecules into bioactive degraders.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. 3/ Cell Membrane Editor A cell is a lipid shell with lots of DNA, proteins, and RNA molecules inside. Read Programming inactive RNA-binding small molecules into bioactive degraders.

DNA 52