Practical Cheminformatics

JANUARY 8, 2024

In November and December, several large pharmas held “AI Day” presentations featuring LLM applications for clinical trial data analysis. Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce.

Drugs 139

Drugs Small Molecule Bioinformatics Packaging 139

Codon

MAY 30, 2023

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. Read Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial. ‘OK’ to start clinical trials.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

This means that IscB base editors might be easier to package inside of AAVs, which can only store 4,700 bases of DNA for gene therapies. Read Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial. ‘OK’ to start clinical trials.

DNA 52

DNA RNA Engineering Vaccine 52

Agency IQ

MAY 31, 2024

Even small changes in the Parliament’s composition could have an impact on ongoing legislative discussions, such as the revisions to the pharma reform package. The current European Parliament and Commission have confirmed their position on the pharma package, but the European Council is still working on its negotiation position.

Regulations 40

Regulations Production Compliance Pharmaceuticals 40

Codon

JUNE 26, 2023

A live demo is available online, but “it chews through OpenAI credits,” Patel says. There’s a live demo available online. “Right now, it can only make one protein at a time,” Gershon says, simply because the demo has limited compute resources. “Every query is like $2.” A Mycoplasma cell.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

A live demo is available online, but “it chews through OpenAI credits,” Patel says. There’s a live demo available online. “Right now, it can only make one protein at a time,” Gershon says, simply because the demo has limited compute resources. “Every query is like $2.” A Mycoplasma cell.

DNA 52

DNA Therapies Engineering Clinical Trials 52