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Largest-ever genetic study of epilepsy finds possible therapeutic targets

Broad Institute

In the future, the results could also help doctors tailor treatments to a patient’s genome. Epilepsy also has several subtypes, and while one group called developmental encephalopathies have been connected to several genes, other forms of the disease are less well understood. Epilepsy is one of the most common neurological disorders.

DNA 72
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Pauline’s Superhero Story

KIF1A

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. One day later, we arrived at the hospital. A cheek swab DNA test was performed at the hospital, which also resulted as normal. Pauline born weighing 2.645 kg and measuring 45 cm.

Doctors 52
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Marvin Caruthers receives inaugural Merkin Prize in ceremony at the Broad Institute for DNA synthesis technology

Broad Institute

Related links Merkin Prize Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA The inaugural Richard N. Caruthers was announced as the winner in June for his development, in 1981, of an efficient, automated technology for synthesizing DNA.

DNA 52
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How the Classic TB Vaccine Treats Bladder Cancer – Zebrafish Avatars Reveal Mechanism

PLOS: DNA Science

One of the oldest and most successful immunotherapies is simpler: a tamed version of a classic vaccine, against the infectious disease tuberculosis (TB). Their report appears in Disease Models and Mechanisms. He and other doctors who used them reported excellent results, especially in bone and soft-tissue sarcomas.

Vaccine 52
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Combination therapy halts lung cancer tumour growth in mice

Drug Discovery World

Mosammaparast published a paper in the journal Nature in 2017 describing how cancer cells repair a kind of DNA damage known as alkylation damage, the kind caused by cyclophosphamide, noting that RNF113A plays a role in the process. One of the challenges we will face is convincing doctors to go back to an old drug.

Therapies 130
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Not all neoantigens are created equal

Drug Target Review

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell.

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A close research partnership with African scientists helps solve the mystery of malaria-like illnesses

Broad Institute

By Claire Hendershot March 8, 2024 Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health via U.S. There are a lot of patients that they couldn’t treat unless it was malaria or a small host of other diseases. The bacteria causes infections with malaria-like symptoms.

Research 111