Broad Institute

DECEMBER 6, 2023

Cytokines are also targeted by drugs for many diseases such as rheumatoid arthritis, COVID-19, and cancer, but until now, scientists haven’t had a comprehensive view of how different immune cells respond to different cytokines because the immune system is so complex. For many immune-mediated diseases, there's no cure or treatment.

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Immune Response RNA Disease Medical Schools 138

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. This New Alternative Model (NAM) provides a platform for High-Content Screening through disease modeling through the transplantation of primary patient tumors into immunocompromised lines.

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Disease Medical Schools Pharma Companies Clinical Trials 59

The Pharma Data

DECEMBER 1, 2020

1, 2020 — Yet another grim record for COVID-19 hospitalizations was set on Monday, as more than 96,000 patients battled severe cases of the virus in hospital wards across America. But the number of hospitalizations have risen by more than 12 percent over the past week, the newspaper noted. TUESDAY, Dec. California Gov.

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Hospitals Vaccine Virus Government 52

Codon

AUGUST 27, 2024

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. Sometimes, though, novel diseases do emerge, and as COVID-19 demonstrated, they can surprise us. This is the third essay of four in our pandemic mini-issue.

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DNA Laboratories Hospitals Virus 97

The Pharma Data

JANUARY 15, 2021

13 in the New England Journal of Medicine , involved patients with high blood pressure in the lungs caused by interstitial lung disease (ILD). It can have a range of causes, from smoking, to occupational exposure to toxins like asbestos, as well as autoimmune diseases like rheumatoid arthritis. The study, published online Jan.

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Disease Doctors Trials FDA Approval 52

Broad Institute

JANUARY 18, 2024

The team says that these priming agents could improve the performance of liquid biopsies for cancer and potentially other diseases — akin to how contrast agents are given to patients to enhance medical imaging scans. Their findings are published in Science. Circulating tumor DNA levels in the animals returned to baseline within a day. “The

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DNA Engineering Science Disease 133

The Pharma Data

JANUARY 5, 2021

Centers for Disease Control and Prevention. These children often miss school and social activities due to doctors’ visits or health restrictions. Of those, 1,164 had congenital heart disease. The defects range from mild to severe and sometimes require immediate or multiple surgeries. who reviewed the findings.

Disease 52

Disease Hospitals Doctors Treatment 52

Broad Institute

MAY 30, 2023

By Andrea Tamayo May 30, 2023 Credit: Allison Dougherty, Broad Communications Isabella Teixeira-Soldano studies single cells to better understand disease progression. When I went to school, I was set on becoming a doctor. Then he asked, “Well, why do you want to be a doctor?” What inspired you to do research as an undergrad?

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Research Medical Schools Doctors Science 89

The Pharma Data

DECEMBER 3, 2020

Centers for Disease Control and Prevention warned Wednesday that the coming winter months might be the darkest period yet in the coronavirus pandemic. Another record-breaking day of COVID-19 hospitalizations and deaths underscored Redfield’s grim warning. Doctors say this reflects India’s younger and leaner population.

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Hospitals Vaccine Long-Term Care Facilities Nurses 52

Broad Institute

MARCH 8, 2024

By Claire Hendershot March 8, 2024 Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health via U.S. There are a lot of patients that they couldn’t treat unless it was malaria or a small host of other diseases. The bacteria causes infections with malaria-like symptoms.

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Research Disease Medical Schools RNA 111

The Pharma Data

DECEMBER 3, 2020

4, 2020 /PRNewswire/ — Body Doctor specializes in eye-care, eyelid hygiene products and have transformed the market for eye compresses and continue establishing a pedigree of bringing innovation to the sector with an antibacterial fabric thanks to the partnership with Polygiene®. About Body Doctor. STOCKHOLM , Dec.

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Doctors Production Hospitals Marketing 40

Drug Target Review

JANUARY 23, 2024

In April 2023, we saw the first randomised data applying an individualised vaccine in combination with checkpoint inhibition for resectable melanoma, demonstrating benefit in terms of time to disease recurrence.

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Treatment Immune Response Vaccine Therapies 122

Drug Target Review

OCTOBER 1, 2024

Since I was a child, I always wanted to be a doctor. From a human point of view, I have always considered doctors’ work as a sort of mission for the good of others. Being a doctor means giving courage and hope day in, day out to those experiencing illness.

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Doctors Therapies Science Pharma Companies 97

Broad Institute

FEBRUARY 8, 2024

Researchers uncover genetic factors for severe Lassa fever By Allessandra DiCorato February 8, 2024 Breadcrumb Home Researchers uncover genetic factors for severe Lassa fever New findings from an international collaboration pave the way for studies of highly infectious diseases in Africa such as Ebola. Chan School of Public Health.

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Research Virus Hospitals Disease 81

Broad Institute

MAY 2, 2024

If we can understand how those processes work, we can better develop drugs to target these multifaceted diseases. With rapid autopsies, you can look at a cancer’s life and see how it developed from a primary to metastatic disease. In undergrad, I thought about going to medical school, but I didn’t want to work in a hospital.

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Science Medical Schools Disease Hospitals 124

The Pharma Data

JANUARY 11, 2021

Surprisingly, the severity of patients’ initial COVID-19 infections were not a factor: People who’d managed at home were as likely to feel unwell as those who’d been hospitalized. Luis Ostrosky, a professor of infectious diseases at McGovern Medical School at UTHealth in Houston, is among the doctors seeing long haulers.

Doctors 52

Doctors Hospitals Medical Schools Disease 52

Broad Institute

JULY 10, 2023

Credit: Allison Colorado, Broad Communications Arriving in the Bay Area after a childhood in increasingly diverse surroundings, Martin became acutely aware of health disparities and the profound differences in disease prevalence among different populations. I wanted to know how I could have any impact on studying genetic diversity.”

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Disease Bioinformatics Medical Schools Research 98

The Pharma Data

NOVEMBER 30, 2020

30, 2020 — Repeat this: The key to helping people with diabetes stay healthier and out of the hospital could be as simple as better communication. They were also less likely to be hospitalized with diabetes-related complications. So why don’t more doctors use this approach? MONDAY, Nov.

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Doctors Medical Schools Hospitals Disease 52

The Pharma Data

JULY 8, 2021

” Heart failure poses a significant global disease burden: more than 60 million patients worldwide have heart failure, and half of them have HFpEF. Heart failure is a leading cause of hospitalization and is becoming increasingly prevalent in Western countries due to aging populations. vice president, Product Development, Lilly.

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Trials Doctors Hospitals Clinical Trials 52

KIF1A

MAY 29, 2024

Fortunately, Sloane does not currently have epilepsy, and Megan hopes this treatment will prevent it’s onset as her disease progresses. On the day of the treatment, they checked into the hospital where Sloane was administered sedation medication. During sedation, Sloane also had an MRI to assess for cerebral atrophy.

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Treatment Doctors Hospitals Therapies 52

KIF1A

AUGUST 20, 2024

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. One day later, we arrived at the hospital. A cheek swab DNA test was performed at the hospital, which also resulted as normal. Pauline born weighing 2.645 kg and measuring 45 cm.

Doctors 52

Doctors Hospitals DNA Therapies 52

Broad Institute

JANUARY 30, 2024

Bhattacharyya, who is an assistant professor in the Infectious Diseases Division of Massachusetts General Hospital Department of Medicine, where he is an attending physician, explains how his roles as a doctor and as an experimental researcher inform one another in valuable ways.

Doctors 52

Doctors Hospitals Disease Research 52

Broad Institute

OCTOBER 23, 2024

Scientist II Michael Trembley is a scientist II at the Precision Cardiology Laboratory (PCL) of the Broad Institute and Bayer, where his research is focused on discovering and validating novel therapeutic targets for heart disease. Trembley holds a Ph.D. in pharmacology from the University of Rochester.

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Medical Schools Engineering Laboratories Doctors 52

The Pharma Data

DECEMBER 7, 2020

7, 2020 — Early in the COVID-19 pandemic, doctors became concerned that people were delaying needed medical care to avoid hospitals. It’s usually treated as a medical emergency, with doctors often surgically removing the appendix to keep it from rupturing. MONDAY, Dec. adults were forgoing needed medical care.

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Hospitals Doctors Research Treatment 52

The Pharma Data

JANUARY 20, 2021

Department of Veterans Affairs (VA) hospitals, researchers found a pattern: COVID-19 patients were nearly twice as likely to die during periods when ICUs were dealing with a surge of patients with the illness. “This shouldn’t make people afraid to go to the hospital,” he said. WEDNESDAY, Jan.

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Medical Schools Hospitals Doctors Disease 52

The Pharma Data

DECEMBER 7, 2020

” Instead, the 44-year-old former policy analyst who lives in Austin, Texas, is still weak and in pain, with ailments doctors are still trying to treat. ” This state of limbo is now being called long COVID or long-haul COVID, and doctors are still trying to figure it out. She’s worried about the future.

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Doctors Hospitals Virus Disease 52

Codon

JANUARY 21, 2024

Today, refined versions of these human challenge studies have become standard practice in testing vaccines for vector-borne diseases (e.g., yellow fever, malaria, and dengue), evaluating new drugs or treatments, and studying pathogenesis, the process by which a disease develops. How are disease targets selected for challenge trials?

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The Pharma Data

JANUARY 26, 2021

“The death toll from COVID-19 continues to rise around the world and hospitalizations, particularly in the U.S., These data further support our belief that bamlanivimab and etesevimab together have the potential to be an important treatment that significantly reduces hospitalizations and death in high-risk COVID-19 patients.

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Hospitals Treatment Trials Long-Term Care Facilities 52

Broad Institute

FEBRUARY 11, 2025

Immunologist Lloyd Bod will take us on a tour of the immune system, and discuss new insights that may help scientists and doctors leverage its cancer-fighting capabilities more effectively. Learn more about the Broad Discovery Series.

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Medical Schools Immune Response Hospitals Doctors 52

PPD

MAY 18, 2023

For neurodegenerative disease research, the care partner, or caregiver, is equally important as the person with dementia. The care partners are the decision-makers for their loved ones with neurodegenerative disorders, handling everything from daily routines and medication management to doctor visits.

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Clinical Trials Trials Clinical Research Doctors 86

The Pharma Data

JUNE 26, 2021

There are currently no FDA-approved anticoagulation therapies for pediatric patients with congenital heart disease who have undergone the Fontan procedure, a surgical procedure that redirects blood flow from the lower body to the lungs. If approved, XARELTO ® will be the first and only oral Factor Xa inhibitor indicated in the U.S.

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Doctors Treatment Hospitals Clinical Trials 52

The Pharma Data

JULY 22, 2021

NOTE: ADUHELM TM (aducanumab-avwa)injection 100 mg/mL solutionis indicated for the treatment of Alzheimer’s disease. Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials. Biogen Inc.

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The Pharma Data

DECEMBER 9, 2020

In the new study, researchers found that among COVID patients at their safety-net hospital, neurological complications ran the gamut. Safety-net hospitals are obligated, by mandate or mission, to treat people regardless of their ability to pay. In her study group, 10 patients died in the hospital. The findings, published Dec.

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Hospitals Immune Response Doctors Virus 52

The Pharma Data

SEPTEMBER 2, 2020

Media caption Katherine Millbank spent 15 days in hospital and was part of the Recovery trial. “It was a very worrying time, yet less than six months later we’ve found clear, reliable evidence in high quality clinical trials of how we can tackle this devastating disease.” Media playback is unsupported on your device.

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Clinical Trials Doctors Trials Hospitals 52

The Pharma Data

DECEMBER 10, 2020

Centers for Disease Control and Prevention will also vote on whether to recommend the vaccine and for whom, the Post reported. The FDA panel included all-star experts on immunology, virology and infectious diseases. Third of Americans live where hospitals short on ICU beds. An advisory committee to the U.S. and Troy, Mich. —

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Vaccine FDA Long-Term Care Facilities Hospitals 52

The Pharma Data

DECEMBER 23, 2020

23, 2020 — Because COVID-19 is known to raise the odds for dangerous blood clots, blood thinners have quickly become part of routine care for many hospitalized patients. One doctor on the frontlines of the pandemic agreed that full-dose anticoagulants come with hazards. WEDNESDAY, Dec.

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Trials Hospitals Clinical Trials Doctors 52

The Pharma Data

DECEMBER 31, 2020

Patients must deal with multiple layers of doctors, specialists, pharmacists and insurers to have their ailments treated. “In the United States, if you’re on Medicare and you have multiple chronic illnesses, you can have more than 10 doctors. Well, that isn’t good. .” “Those are complex tasks. .

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