The Pharma Data

NOVEMBER 20, 2020

20, 2020 — Hormone therapy can be a lifesaver for men with prostate cancer , but it also appears to put some at increased risk of heart problems, a new study reports. At the start of the study, 4 out of 5 men had two or more risk factors for heart disease , the study says. FRIDAY, Nov.

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Drug Target Review

JANUARY 23, 2024

In April 2023, we saw the first randomised data applying an individualised vaccine in combination with checkpoint inhibition for resectable melanoma, demonstrating benefit in terms of time to disease recurrence. We anticipate this area to grow, especially cancer vaccines, with important read-outs expected across various cancer types in 2024.

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On Medicine

FEBRUARY 26, 2023

Behçet’s disease is a rare multisystem vasculitic disorder that can affect any of the blood vessels of the body; signs and symptoms are diverse among individuals and range in severity, but often present as recurrent oral aphthous ulcers, genital ulcers, or as complications involving the eyes.

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Drug Discovery World

JULY 29, 2022

From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease. muciniphila’s ability to manipulate the immune system and fight disease. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness. New doors open.

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PPD

MAY 18, 2023

For neurodegenerative disease research, the care partner, or caregiver, is equally important as the person with dementia. The care partners are the decision-makers for their loved ones with neurodegenerative disorders, handling everything from daily routines and medication management to doctor visits.

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Drug Target Review

DECEMBER 28, 2023

In most cancers, the tumour evolves by acquiring mutations that confer growth advantages or resistance to therapies. Involving more than 250 investigators based at 19 hospital sites across the UK, the study has analysed genetic signatures in lung tumours, tracking how they have evolved over the past nine years in more than 815 patients.

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Drug Target Review

FEBRUARY 26, 2024

Regarding therapy resistant melanomas, why is the alteration of the epigenetic landscape considered significant, and what has been lacking in terms of validated targetable epigenetic mechanisms? What is remarkable here is that we show that the addition of corin to BRAFi-resistant tumour cells resensitises them to BRAFi therapies.

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Drug Discovery World

JUNE 5, 2023

Showcase agenda Throughout the day, there were a number of presentations on the exhibition floor which provided company updates and showcased a number of exciting results and projects, highlighting both how far we have come in the treatment of disease, as well as how far there is still to go.

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The Pharma Data

JULY 22, 2021

NOTE: ADUHELM TM (aducanumab-avwa)injection 100 mg/mL solutionis indicated for the treatment of Alzheimer’s disease. Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.

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The Pharma Data

JANUARY 21, 2021

That included 71% of patients with relapsing-remitting MS, the most common form of the disease. Most people, though, eventually transition to a progressive form of the disease, and their disability worsens over time. It requires a long hospital stay, plus a period of months when patients are severely immunocompromised, Bebo said.

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Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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The Pharma Data

JANUARY 17, 2021

The treatment could be administered in primary care centers to people who test positive for COVID-19, avoiding hospitalization due to the progression of the disease and complementing the vaccine in the early phase after vaccination. BARCELONA, Spain , Jan. 18, 2021 /PRNewswire/ — Grifols (MCE: GRF, MCE: GRF.P,

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The Pharma Data

DECEMBER 3, 2020

It focuses on treatment tailored for different age groups and severity of disease. Depending on the severity of disease, there are many options for treating asthma. Centers for Disease Control and Prevention. Without treatment, asthma can limit activities and cause flare-ups that can result in hospitalization or even death.

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The Pharma Data

FEBRUARY 1, 2021

By getting what is known as a ‘high tibial osteotomy,’ younger patients with less severe joint damage who are physically active might be able to delay the need for a knee replacement by 10 years or more, though they may have to search for a doctor who performs the surgery. “Ask your doctor, “Would this be right for me?

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The Pharma Data

JUNE 1, 2022

Anderson most recently served as Vice President and Chief Scientific Officer for Bacterial Research and Hospital within the Vaccine R&D organization. Dr. Anderson earned her doctorate in Biological Sciences at the University of Warwick in the field of microbial ecology and then completed two post-doctoral fellowships.

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Codon

JANUARY 21, 2024

Today, refined versions of these human challenge studies have become standard practice in testing vaccines for vector-borne diseases (e.g., yellow fever, malaria, and dengue), evaluating new drugs or treatments, and studying pathogenesis, the process by which a disease develops. How are disease targets selected for challenge trials?

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The Pharma Data

JANUARY 27, 2021

Cardiac rehab programs have long been offered to people with heart disease. Yet insurance does not cover the therapy for stroke patients. “There’s a short-sightedness in how we allocate resources,” said Schwamm, who is also executive vice-chairman of neurology at Massachusetts General Hospital, in Boston.

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NIH Director's Blog: Drug Development

APRIL 2, 2020

With so much information swirling around these days about the coronavirus disease 2019 (COVID-19) pandemic, it would be easy to miss one of the most interesting and significant basic science reports of the past few weeks. This is of particular concern to doctors whose patients are already taking the medications to control hypertension.

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The Pharma Data

JANUARY 20, 2021

The approval of Verquvo by the FDA, which is the first treatment for chronic heart failure approved specifically for patients following a hospitalization for heart failure or need for outpatient IV diuretics, is based on the results of the pivotal Phase 3 VICTORIA trial and follows a priority regulatory review. Verquvo (vericiguat) 2.5

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The Pharma Data

MAY 4, 2021

Amid the coronavirus pandemic, concern has grown over the potential neglect of other serious diseases. Multiple sclerosis (MS), for example, is a condition for which timely diagnosis, early treatment and the development of innovative therapies are particularly important for reducing the disabling progress of the disease.

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The Pharma Data

FEBRUARY 12, 2022

Doctors call this drug ‘bari,’ and receiving the pill once a day for up to 14 days yielded one of the largest a survival advantages seen yet in the COVID pandemic, according to a study published in The Lancet Respiratory Medicine. Source link: [link].

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The Pharma Data

NOVEMBER 17, 2020

It’s a minimally invasive procedure in which doctors use heat or cold to destroy bits of heart tissue that are generating the faulty electrical signal causing the arrhythmia. And only 11% of ablation patients had an episode that caused symptoms — compared with 26% of those on drug therapy.

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Broad Institute

JULY 26, 2022

By Stephanie Dutchen, Harvard Medical School Office of Communications and External Relations July 26, 2022 Credit: Susanna Hamilton, Broad Communications From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease. Study after study had suggested that A.

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The Pharma Data

JULY 21, 2021

mg, 5 mg, and 10 mg) is indicated for the treatment of symptomatic chronic heart failure in adult patients with reduced ejection fraction who are stabilized after a recent decompensation event requiring intravenous (IV) therapy. In the EU, VERQUVO (2.5 VERQUVO is being jointly developed by Merck and Bayer AG. In January of this year, the U.S.

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Codon

FEBRUARY 13, 2024

Tom Ireland writes about the companies and technologies that are reimagining phage therapy. Soon after its publication, scientists, journalists, and investors were revisiting ‘phage therapy’ as a promising alternative to our failing antibiotics. alone, according to the Centers for Disease Control and Prevention.

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The Pharma Data

MAY 4, 2021

Asthma is not a ‘one size fits all’ disease. When you think about it, it’s not surprising that a disease that affects more than 1/3 of a billion people worldwide 1 manifests in different ways for different people, but it is frequently mischaracterized. . Seeking novel therapies against a range of respiratory diseases.

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The Pharma Data

OCTOBER 19, 2020

New Guidance: The FDA issued and implemented new guidance, Enforcement Policy for Modifications to FDA-Cleared Molecular Influenza and RSV Tests During the Coronavirus Disease 2019 (COVID-19) Public Health Emergency. Testing Therapies, Antivirals and Vaccines. Please read more here. . Please read more here. .

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Alta Sciences

JUNE 27, 2023

I was offered two treatment options: The first was a standard chemo treatment called Hyper-CVAD and the other was a clinical trial that my doctor highly recommended because I had a G mutation. And after the first round of chemo, I was almost completely disease-free. I met her when I was in the hospital for my transplant.

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The Pharma Data

AUGUST 3, 2021

The company’s success is based on its rich R&D portfolio with a focus on diseases with high unmet medical need. More than 60 million patients worldwide suffer from this disease, approx. Despite all the medical progress made in recent decades, there are still many diseases for which there is yet no adequate treatment available.

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The Pharma Data

MAY 15, 2021

If You or Someone You Love is Suffering From Chronic Fatigue Syndrome, Then This Will Be the Most Important Letter You Will Ever Read… “Doctors Told Me There Was No Cure For Chronic Fatigue Syndrome…But Contrary To Their Prediction, I Got My Life Back From My CFS…100% Naturally! Description: ATTENTION!

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The Pharma Data

JUNE 28, 2021

After seeing a doctor, he was diagnosed with plaque psoriasis—a chronic autoimmune disease that appears on the surface of the skin as raised, red, itchy patches, but actually starts inside the body, caused by dysfunction of the immune system. 1 About 80 percent of the over 8 million people living in the U.S. Otezla ® (apremilast) U.S.

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The Pharma Data

DECEMBER 20, 2020

Cefepime/enmetazobactam will be a welcome addition to the tools that doctors have to help their patients, and we look forward to introducing this antibiotic to hospitals and achieving a win-win collaboration.”. Cefepime/enmetazobactam has been granted Qualified Infectious Disease Product and Fast Track designation by the U.S.

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Codon

JULY 14, 2024

While this departs from the reductionist, single-component therapies that have dominated transfusion medicine since World War II, emerging data underscores that whole blood transfusions—blood with all its parts—yield better outcomes following severe blood loss than transfusions involving discrete blood components. Always free.

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Broad Institute

JANUARY 30, 2024

Bhattacharyya wears many coats today, splitting his time between the Broad and the infectious disease ward at MGH, where a diagnostic method he developed at Broad is now being tested to see if it helps patients quickly receive the best antibiotics for their infections.

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The Pharma Data

JULY 8, 2021

” Heart failure poses a significant global disease burden: more than 60 million patients worldwide have heart failure, and half of them have HFpEF. Heart failure is a leading cause of hospitalization and is becoming increasingly prevalent in Western countries due to aging populations. vice president, Product Development, Lilly.

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The Pharma Data

JANUARY 26, 2021

percent) in patients taking therapy and 36 events (7.0 Bamlanivimab and etesevimab together also demonstrated statistically significant improvements on all key secondary endpoints, providing strong evidence that the therapy reduced viral load and accelerated symptom resolution. who require oxygen therapy due to COVID-19, OR.

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Codon

JULY 27, 2023

CNGA3-achromatopsia is a hereditary disease that causes people to see in shades of gray. But what happens if you restore these cone cells, using gene therapy? There’s a TV show where a bunch of doctors are walking through a hospital corridor. They’re talking about a patient who has a rare genetic disease.

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