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Turning science into business: An optimised alternative to antibodies

Drug Discovery World

DS: What motivated you and Dr David Bunka, CTO, to create Aptamer and did you imagine you would one day be operating on such a global scale?    AT : We initially met at the University of Leeds, where David was a post-doctoral researcher studying aptamers, and I was completing my PhD.

Science 130
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The democratisation of cell and gene therapy

Drug Discovery World

DNA purification “Plasmid DNA is an incredibly important part of molecular biology”, says Hummersone. He says: “What we are seeing from a molecular biology perspective is that the genetic material that we want to pack into viral vectors is becoming increasingly complicated. Firstly, AAV is a delicate vector.

Therapies 273
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Battling antibiotic resistance in the lab and the clinic

Broad Institute

Bhattacharyya wears many coats today, splitting his time between the Broad and the infectious disease ward at MGH, where a diagnostic method he developed at Broad is now being tested to see if it helps patients quickly receive the best antibiotics for their infections.

Hospitals 137
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Scaling Phage Therapy

Codon

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

Therapies 118
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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Alessa Schaffrath, Doctoral Student, UKE Hamburg, on: ‘Transgenic llama mice – a fast and flexible single domain discovery tool’. Phil Leighton, PhD, Senior Director, Molecular Biology, OmniAb, on: ‘Heavy chain-only transgenic chickens produce human antibodies with robust immune repertoires and high-affinity binding’.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

CNGA3-achromatopsia is a hereditary disease that causes people to see in shades of gray. in Current Biology. There’s a TV show where a bunch of doctors are walking through a hospital corridor. They’re talking about a patient who has a rare genetic disease. ” Gene-edited poplar tree stems appear red.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

CNGA3-achromatopsia is a hereditary disease that causes people to see in shades of gray. in Current Biology. There’s a TV show where a bunch of doctors are walking through a hospital corridor. They’re talking about a patient who has a rare genetic disease. ” Gene-edited poplar tree stems appear red.