SCIENMAG: Medicine & Health

JULY 28, 2023

Pearson, co-author of the paper, is now a NEWVEC post-doctoral researcher at UMass Amherst. Lynch, lead author, is now a research fellow in the Department of Veterinary and Animal Sciences. The discovery began with an “aha” moment by then-Ph.D. Credit: UMass Amherst […]

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Research Therapies Disease Doctors 82

Drug Target Review

SEPTEMBER 22, 2023

Organoid technologies are becoming an invaluable solution for preclinical research, with the ability to augment the development of personalised medicine, drug discovery and gene therapies. The derived drug was given to both patients, to which researchers report the patients saw significant improvement.

Clinical Research 116

Clinical Research Research Drug Development Molecular Biology 116

Broad Institute

MARCH 8, 2024

By Claire Hendershot March 8, 2024 Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health via U.S. There are a lot of patients that they couldn’t treat unless it was malaria or a small host of other diseases. The bacteria causes infections with malaria-like symptoms.

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Research Disease Medical Schools RNA 111

Broad Institute

MAY 30, 2023

#WhyIScience Q&A: A process development lead returns to her research roots By Corie Lok May 30, 2023 Breadcrumb Home #WhyIScience Q&A: A process development lead returns to her research roots Isabella Teixeira-Soldano reflects on her time as a technician in Broad’s COVID-19 testing lab and how that led to a position doing single-cell research.

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Research Medical Schools Doctors Science 89

Drug Discovery Today

JANUARY 13, 2021

Mission: Cure is a coalition of patients, doctors, researchers and entrepreneurs who are committed to advancing new therapies and cures for currently untreatable diseases. Their primary disease focus is on chronic pancreatitis, a rare inflammatory condition that affects over a million people across the globe.

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Treatment Doctors Disease Therapies 113

Broad Institute

OCTOBER 3, 2024

In the future, the results could also help doctors tailor treatments to a patient’s genome. Epilepsy also has several subtypes, and while one group called developmental encephalopathies have been connected to several genes, other forms of the disease are less well understood. Epilepsy is one of the most common neurological disorders.

DNA 133

DNA Doctors Treatment Disease 133

Broad Institute

JUNE 18, 2024

Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. Myhrvold, who is currently an assistant professor at Princeton University, was a postdoctoral researcher in Sabeti’s lab when the study began.

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Virus RNA Laboratories Medical Schools 144

Antidote

JANUARY 29, 2024

Not only will patients be able to gain access to potential new treatments, but they will also be directly contributing to research that can save lives — something that Jamie Troil Goldfarb has experienced firsthand. Jamie received a diagnosis of stage IV melanoma in 2011, only 11 weeks after giving birth to her child.

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Clinical Trials Trials Doctors Treatment 122

SCIENMAG: Medicine & Health

JUNE 16, 2023

In humans, neurogenesis lasts particularly long compared with other species, explains Khadijeh Shabani, a post-doctoral researcher […] It is a complex process with finely tuned mechanisms. “In

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Disease Doctors Research 71

The Pharma Data

DECEMBER 10, 2020

Dr. Pirozzi received a Doctorate of Medicine from Università Campus Bio-Medico di Roma in Italy, a Doctorate of Philosophy in Immunology from Sapienza Università di Roma in Italy, a Post-Doctorate degree in Immunology from the Institut Pasteur in Paris, France, and business training at the London Business School, UK.

Disease 52

Disease Research Doctors Clinical Development 52

Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Biomarker information is also useful for tracking progression of the disease and treatment response. Most drugs do not work in all people.

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Doctors Clinical Trials Treatment Therapies 111

The Pharma Data

AUGUST 22, 2021

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. “There’s often a phenomenon that doctors report anecdotally, or that’s mentioned in passing in a particular research paper, and that provides a clue – a hook,” he said. The next challenge was to figure out why.

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Doctors Drugs Immune Response Virus 52

Drug Target Review

DECEMBER 13, 2023

Combinatorial analytics approaches identify combinations of features that together are associated with the disease phenotype in patient sub-groups, capturing the non-linear effects of interactions between multiple genes. The combinatorial approach is considerably more sensitive than GWAS and requires much smaller patient populations.

Bioinformatics 145

Bioinformatics Disease Regulations Immune Response 145

Broad Institute

OCTOBER 23, 2024

The family was instrumental in the research that led to the discovery and her diagnosis. They knew that discovering the genetic cause of her disorder would help them find other people like her, help get the condition formally recognized as a new disease, and help them better advocate for research into new treatments.

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DNA RNA Disease Hospitals 128

Drug Target Review

OCTOBER 25, 2024

How does precision neuroscience differ from traditional approaches in the treatment of neurodegenerative diseases, and what advantages does it offer? Traditionally, Alzheimer’s disease is diagnosed by clinical examination, medical history and cognitive testing. We believe we are at a breakthrough moment in Alzheimer’s disease research.

Disease 59

Disease Clinical Trials Therapies Science 59

SCIENMAG: Medicine & Health

NOVEMBER 27, 2023

27, 2023 – Common neuropsychiatric symptoms that doctors see in Alzheimer’s disease patients originate from brain inflammation rather than amyloid and tau proteins, report University of Pittsburgh School of Medicine researchers today in JAMA Network Open. PITTSBURGH, Nov. Credit: UPMC PITTSBURGH, Nov.

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Doctors Disease Research 73

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. How can research boost the discovery of specific therapies for childhood and adolescent cancers? This treatment was developed by performing a chemical screening on zebrafish.

Disease 59

Disease Medical Schools Pharma Companies Clinical Trials 59

KIF1A

OCTOBER 21, 2023

Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. The Study To investigate precursor vesicle trafficking, the researchers used neurons derived from human induced pluripotent stem cells (iPSCs).

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Regulations Doctors Disease Packaging 105

Drug Target Review

OCTOBER 9, 2023

Researchers from the University of Helsinki and the National Institutes of Health (NIH) in the United States have made a new discovery: the ectoderm, one of the germ layers, does not lose its pluripotency during gastrulation, contrary to prior beliefs. The newfound insights hold the potential to enhance comprehension of a range of diseases.

Therapies 110

Therapies Doctors Disease Research 110

Broad Institute

JANUARY 18, 2024

The team says that these priming agents could improve the performance of liquid biopsies for cancer and potentially other diseases — akin to how contrast agents are given to patients to enhance medical imaging scans. Funding: This research was supported by Louis V. Their findings are published in Science. Gerstner, Jr.,

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DNA Engineering Science Disease 133

Alta Sciences

JUNE 12, 2024

Before becoming a study director, Ashley held the position of Research Technician II. As Staff Research Associate II at the University of California, Davis, she performed rodent survival surgeries, conducted electrophysiological recordings, managed lab operations, and analyzed data for scientific manuscripts.

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Doctors International Research Science 98

The Pharma Data

OCTOBER 23, 2020

23, 2020 — High levels of a protein that lubricates the knee joint may actually be a harbinger of impending joint disease, a surprising animal study suggests. “We know that if a person or animal doesn’t make that protein, they will develop devastating joint disease affecting all the major weight-bearing joints.”

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Disease Doctors Research Treatment 52

The Pharma Data

JANUARY 15, 2021

13 in the New England Journal of Medicine , involved patients with high blood pressure in the lungs caused by interstitial lung disease (ILD). It can have a range of causes, from smoking, to occupational exposure to toxins like asbestos, as well as autoimmune diseases like rheumatoid arthritis. The study, published online Jan.

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Disease Doctors Trials FDA Approval 52

PPD

MAY 18, 2023

For neurodegenerative disease research, the care partner, or caregiver, is equally important as the person with dementia. The care partners are the decision-makers for their loved ones with neurodegenerative disorders, handling everything from daily routines and medication management to doctor visits.

Clinical Trials 86

Clinical Trials Trials Clinical Research Doctors 86

Drug Target Review

FEBRUARY 29, 2024

During my academic career, I had the opportunity to examine the underlying causes of neurodegenerative diseases like Parkinson’s disease and develop novel animal models to investigate potential disease-modifying therapeutics. For instance, we know ageing is a primary risk factor for many neurodegenerative diseases.

Therapies 111

Therapies Disease Clinical Trials Science 111

The Pharma Data

NOVEMBER 30, 2020

30, 2020 — The first blood test to help diagnose Alzheimer disease is now available in the United States, but some experts have a number of concerns about it. Louis is meant for people 60 years and older who have cognitive issues and are being assessed for Alzheimer disease. MONDAY, Nov. The test from C2N Diagnostics of St.

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Disease FDA Approval Doctors Government 52

Broad Institute

JULY 26, 2022

Researchers decipher how a gut bacterium influences immunity By Corie Lok July 26, 2022 Breadcrumb Home News Researchers decipher how a gut bacterium influences immunity Study finds a molecule made by the bacterium that helps moderate immune responses. Study after study had suggested that A. muciniphila ’s cell membrane.

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Research Immune Response Medical Schools Disease 52

KIF1A

MAY 24, 2023

In this blog post, KIF1A.ORG Chief Science Officer Dr. Dominique Lessard describes a unique cross disciplinary experience with multiple scientific stakeholders in the rare disease space, all focused around our holistic understanding of KAND. How do we move the needle to make patient voices and experiences the center of scientific discovery?

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Disease Laboratories Research Science 98

Broad Institute

JULY 10, 2023

Credit: Allison Colorado, Broad Communications Arriving in the Bay Area after a childhood in increasingly diverse surroundings, Martin became acutely aware of health disparities and the profound differences in disease prevalence among different populations. I wanted to know how I could have any impact on studying genetic diversity.”

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Disease Bioinformatics Medical Schools Research 98

Drug Target Review

OCTOBER 1, 2024

Since I was a child, I always wanted to be a doctor. From a human point of view, I have always considered doctors’ work as a sort of mission for the good of others. Being a doctor means giving courage and hope day in, day out to those experiencing illness. Oncology has come a long way in recent years.

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Doctors Therapies Science Pharma Companies 97

Olympian Clinical Research

JUNE 10, 2022

Atopic dermatitis is a form of eczema and is the most common chronic inflammatory skin disease. If you are experiencing any of the above symptoms, it is important to consult with your doctor or dermatologist for an accurate diagnosis. Talk to your doctor about prescription medications that may help relieve itching and inflammation.

Clinical Trials 98

Clinical Trials Clinical Research Doctors Trials 98

Conversations in Drug Development Trends

FEBRUARY 22, 2023

Rare Disease Day on February 28th is a chance for rare disease communities to come together as one and join in conversation with stakeholders searching for treatments, raising money to support research, and changing the way healthcare and governments interact with patients. In my case, my daughter Iris has GM1 gangliosidosis.

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Disease Clinical Trials Trials Treatment 52

Olympian Clinical Research

FEBRUARY 26, 2019

Choosing to participate in a clinical research study is a very personal decision, and people choose to participate in clinical research studies for a variety of reasons. We know that participating in a research study may seem overwhelming and intimidating, but sometimes the potential benefits far exceed any uncertainty.

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Research Clinical Research Clinical Trials Doctors 40

The Pharma Data

JANUARY 5, 2021

Centers for Disease Control and Prevention. These children often miss school and social activities due to doctors’ visits or health restrictions. Of those, 1,164 had congenital heart disease. The defects range from mild to severe and sometimes require immediate or multiple surgeries. 4 in the journal Pediatrics.

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Disease Hospitals Doctors Treatment 52

Drug Target Review

DECEMBER 12, 2023

This has several advantages, including increased speed of development, cost-effectiveness and leveraging already established and extensively researched antibodies. Can you provide more details on ARC-02, Araris’ lead candidate, and what it is designed to treat?

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Treatment Engineering Pharmacokinetics Doctors 114

KIF1A

MAY 27, 2023

Dylan Verden of KIF1A.ORG summarize newly published KIF1A-related research and highlight progress in rare disease research and therapeutic development. Dr. Lessard became part of the KIF1A.ORG community through her graduate research on the biomechanical properties of KIF1A.

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Science Small Molecule Disease Research 94

The Pharma Data

JUNE 1, 2022

has been appointed Senior Vice President and Head of the Company’s Vaccine Research & Development (R&D) organization effective August 1, succeeding Kathrin U. Chief Scientific Officer and President, Worldwide Research, Development and Medical of Pfizer. “I (NYSE: PFE) today announced that Annaliesa Anderson, Ph.D.,

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Vaccine Research Laboratories Doctors 40