Drug Discovery World

JUNE 12, 2023

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW’s Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. It gives the history of the disease and it’s pretty amazing.

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Drug Target Review

JANUARY 23, 2024

What innovative approaches and technologies are anticipated to reshape immuno-oncology treatments in 2024? Immuno-oncology, notably through checkpoint inhibitors, has significantly reshaped cancer treatment over the past decade.

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Advarra

MARCH 10, 2023

Having a one in four chance of developing sickle cell disease (SCD) is uniquely, and overwhelmingly, familiar to the African American population. Considered a rare disease, research in finding better therapies – and possibly even a cure – for SCD may be competing for funding with conditions impacting broader populations.

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Drug Target Review

DECEMBER 12, 2023

This has several advantages, including increased speed of development, cost-effectiveness and leveraging already established and extensively researched antibodies. Can you provide more details on ARC-02, Araris’ lead candidate, and what it is designed to treat?

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Drug Target Review

NOVEMBER 29, 2023

Our primary focus is to design and develop RNA therapies for liver diseases. Using humans as the model, we use an approach called deep phenotyping to explore the relationships between cells, genes, biological pathways and patterns of disease. Why are you focusing on liver disease? As a result, waiting lists continue to grow.

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Drug Discovery World

SEPTEMBER 1, 2022

Scottish scientists are teaming up with researchers from Zambia to find new ways to diagnose and treat a condition which affects millions in Sub-Saharan Africa. . The researchers are working to optimise a prototype breath test built around a process known as isotope ratio infrared spectrometry. Breath test key to diagnosis.

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Drug Discovery World

MARCH 16, 2023

For example, in patients with autoimmune diseases who suffer from uncontrolled T cell activation. In the study, funded by Cancer Research UK and published in Nature , the mice fed diets containing high doses of sucralose were less able to activate T cells in response to cancer or infection.

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biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. How can research boost the discovery of specific therapies for childhood and adolescent cancers? This treatment was developed by performing a chemical screening on zebrafish.

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Drug Discovery Today

JANUARY 13, 2021

Mission: Cure is a coalition of patients, doctors, researchers and entrepreneurs who are committed to advancing new therapies and cures for currently untreatable diseases. Their primary disease focus is on chronic pancreatitis, a rare inflammatory condition that affects over a million people across the globe.

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Broad Institute

OCTOBER 3, 2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets By Ari Navetta October 3, 2024 Breadcrumb Home Largest-ever genetic study of epilepsy finds possible therapeutic targets Scientists have uncovered new genetic links to different types of epilepsy, which could lead to more tailored treatments.

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Drug Discovery World

DECEMBER 18, 2023

However, this robust system can become alarmingly vulnerable when confronted with debilitating conditions like Alzheimer’s, cancer, and cardiovascular diseases. They mark a significant shift in clinical research, utilising technology to capture real-time patient data. Digital biomarkers could be the cornerstone of this evolution.

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Broad Institute

MARCH 8, 2024

By Claire Hendershot March 8, 2024 Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health via U.S. Levine and Siddle say that these findings could improve the precision of diagnostics and treatments in areas with high numbers of NMFI cases.

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Advarra

JUNE 27, 2023

Clinical trials are studies involving human volunteers to research ways to prevent, detect, and treat various medical conditions. Each phase has a different purpose in testing the treatment’s safety and efficacy. Currently incurable diseases would remain so, without any improvements made to existing drugs and therapies.

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Drug Discovery World

JUNE 21, 2024

Allogene Therapeutics and Foresight Diagnostics have announced the initiation of a Phase II trial evaluating the use of cemacabtagene ansegedleucel (cema-cel) as part of the first line treatment regimen for newly diagnosed large B-cell lymphoma (LBCL) patients who are likely to relapse.

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Broad Institute

FEBRUARY 8, 2024

Researchers uncover genetic factors for severe Lassa fever By Allessandra DiCorato February 8, 2024 Breadcrumb Home Researchers uncover genetic factors for severe Lassa fever New findings from an international collaboration pave the way for studies of highly infectious diseases in Africa such as Ebola.

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Drug Target Review

SEPTEMBER 22, 2023

Organoid technologies are becoming an invaluable solution for preclinical research, with the ability to augment the development of personalised medicine, drug discovery and gene therapies. The derived drug was given to both patients, to which researchers report the patients saw significant improvement.

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Drug Discovery World

JULY 29, 2022

Australian researchers based may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold. The findings have been replicated by an independent research group at Novo Nordisk in the United States.

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Antidote

JANUARY 29, 2024

Not only will patients be able to gain access to potential new treatments, but they will also be directly contributing to research that can save lives — something that Jamie Troil Goldfarb has experienced firsthand. Jamie received a diagnosis of stage IV melanoma in 2011, only 11 weeks after giving birth to her child.

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Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Biomarker information is also useful for tracking progression of the disease and treatment response. Most drugs do not work in all people.

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PLOS: DNA Science

OCTOBER 3, 2024

One of the oldest and most successful immunotherapies is simpler: a tamed version of a classic vaccine, against the infectious disease tuberculosis (TB). “BCG” is the “treatment” vaccine’s technical name, for Mycobacterium bovis Bacillus Calmette-Guérin. The approach worked.

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Olympian Clinical Research

SEPTEMBER 16, 2022

million Americans were living with Alzheimer’s disease in 2021, according to the Centers for Disease Control and Prevention (CDC). Alzheimer’s disease is the seventh leading cause of death in the United States and is a devastating disease that can rob people of their memories and lives. Eating a Healthy Diet.

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Olympian Clinical Research

NOVEMBER 9, 2022

Although this disease is estimated to affect less than 50,000 Americans, it may be life-threatening, especially for people who are already in poor health. Therefore, if you or a loved one is dealing with this rare condition, it’s essential to educate yourself about the condition and its potential treatments. Radiation therapy.

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The Pharma Data

AUGUST 22, 2021

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. “There’s often a phenomenon that doctors report anecdotally, or that’s mentioned in passing in a particular research paper, and that provides a clue – a hook,” he said. The next challenge was to figure out why.

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Drug Discovery World

OCTOBER 18, 2023

Sara Donnelly, Director of Research Planning and Business Development at PhoenixBio USA explores why the right pre-clinical model is essential for teams wanting to advance adeno-associated virus vector-based gene therapies. Adeno-associated virus (AAV) vector-based gene therapies hold exceptional promise across a range of disease areas.

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Broad Institute

JUNE 18, 2024

Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. Myhrvold, who is currently an assistant professor at Princeton University, was a postdoctoral researcher in Sabeti’s lab when the study began.

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Drug Discovery World

AUGUST 14, 2024

Even with an approved therapy or a late-stage clinical trial, it’s still not a given that patients or doctors will have access to comprehensive and cost-effective genetic testing. Increasingly, companies are testing multiple different assets in the same disease but with different genetic targets, for example, in breast cancer.

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The Pharma Data

JULY 22, 2021

NOTE: ADUHELM TM (aducanumab-avwa)injection 100 mg/mL solutionis indicated for the treatment of Alzheimer’s disease. Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.

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Olympian Clinical Research

JUNE 2, 2021

Despite its prevalence, there’s still a lot that people don’t understand about atopic dermatitis, its symptoms, and the treatment methods available to patients who suffer from the condition. When it comes to treating atopic dermatitis, most available treatments center around symptom mitigation (i.e. What Causes Atopic Dermatitis?

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Drug Discovery World

SEPTEMBER 5, 2022

The discovery was made by researchers at Washington University School of Medicine in St Louis, Grenoble Alpes University in Grenoble in France, and The University of Texas MD Anderson Cancer Center in Houston. Researchers have found that a chemotherapy drug plus blocking resistance makes the tumours virtually disappear (right).

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Conversations in Drug Development Trends

FEBRUARY 22, 2023

Rare Disease Day on February 28th is a chance for rare disease communities to come together as one and join in conversation with stakeholders searching for treatments, raising money to support research, and changing the way healthcare and governments interact with patients.

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Drug Target Review

JANUARY 30, 2024

Considering the translational potential of this research to clinical applications, what are the key preclinical findings that present the 3A5C7 monoclonal antibody as a promising therapeutic option for managing morphine tolerance in humans? Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.

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Drug Discovery World

JANUARY 22, 2024

For the patient as well as for doctors, this means creating more time to make decisions, as the company believes: “Patients – and their quality of life – shouldn’t have to wait for a broken system to provide an answer six months too late.

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The Pharma Data

JUNE 1, 2022

has been appointed Senior Vice President and Head of the Company’s Vaccine Research & Development (R&D) organization effective August 1, succeeding Kathrin U. Chief Scientific Officer and President, Worldwide Research, Development and Medical of Pfizer. (NYSE: PFE) today announced that Annaliesa Anderson, Ph.D., Jansen, Ph.D.,

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KIF1A

AUGUST 20, 2024

So the pediatrician doctor requested the first cranial tomography, which also gave a normal result. MAKE A GIFT KIF1A.ORG is dedicated to accelerating research to find a cure for superheroes like Pauline. Treatment is within reach, but there are two obstacles in our way: time and money. You can help.

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Alta Sciences

JUNE 27, 2023

Cancer Treatments, Clinical Trials, and the Motivation to Innovate nbartlett Tue, 06/27/2023 - 20:58 Getting to the Heart of Science with Michelle Newby At the heart of science are stories—stories of courage, challenges, successes, lessons, and people. Q: What was your cancer diagnosis and was treatment options were you given?

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National Institute on Drug Abuse: Nora's Blog

FEBRUARY 8, 2023

Pregnant People With Substance Use Disorders Need Treatment, Not Criminalization mfleming Wed, 02/08/2023 - 15:33 Nora's Blog February 15, 2023 Image ©Getty Images/ Caia Image This blog was also published in STAT on February 8, 2023. People seeking treatment for addictions face additional obstacles, especially if they have children.

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Olympian Clinical Research

MARCH 19, 2024

Clinical trials are essential for advancing medical knowledge and developing new treatments that can improve patient care and outcomes. In Tampa Bay, Olympian Clinical Research is at the forefront of this vital work, offering local residents the opportunity to contribute to medical advancements.

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