Drug Discovery World

JUNE 21, 2024

Allogene Therapeutics and Foresight Diagnostics have announced the initiation of a Phase II trial evaluating the use of cemacabtagene ansegedleucel (cema-cel) as part of the first line treatment regimen for newly diagnosed large B-cell lymphoma (LBCL) patients who are likely to relapse.

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Drug Target Review

JANUARY 23, 2024

What innovative approaches and technologies are anticipated to reshape immuno-oncology treatments in 2024? Immuno-oncology, notably through checkpoint inhibitors, has significantly reshaped cancer treatment over the past decade.

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Advarra

MARCH 10, 2023

Having a one in four chance of developing sickle cell disease (SCD) is uniquely, and overwhelmingly, familiar to the African American population. Considered a rare disease, research in finding better therapies – and possibly even a cure – for SCD may be competing for funding with conditions impacting broader populations.

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biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. Zebrafish Pioneers Advance in Pediatric Cancer Research and Treatment Increasing the survival rate is the primary goal when screening for cancer drugs.

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Broad Institute

JANUARY 25, 2024

They found significant associations between the thinning of different retinal layers and increased risk of developing ocular, cardiac, pulmonary, metabolic, and neuropsychiatric diseases and identified genes that are associated with retinal layer thickness. Their findings are published in Science Translational Medicine. “We

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Drug Discovery World

OCTOBER 5, 2023

A research team at the Francis Crick Institute and Great Ormond Street Hospital (GOSH)/UCL Great Ormond Street Institute of Child Health have identified potential treatments for children with rare genetic conditions. The researchers have shown that problems with calcium underlie these progressive diseases.

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Drug Discovery Today

JANUARY 13, 2021

Mission: Cure is a coalition of patients, doctors, researchers and entrepreneurs who are committed to advancing new therapies and cures for currently untreatable diseases. Their primary disease focus is on chronic pancreatitis, a rare inflammatory condition that affects over a million people across the globe.

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Drug Target Review

JUNE 3, 2024

How does COUR Pharmaceuticals’ immune-modifying nanoparticle platform differ from traditional approaches to treating immune-mediated diseases? Essentially, our CNPs reprogramme the immune system by restoring balance and returning the body to a homeostatic state, offering a precise approach to treating immune-mediated diseases.

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Drugs.com

AUGUST 1, 2023

1, 2023 -- Children who have a chronic immune system disease that can prevent them from eating may eventually have a new treatment, decades after the condition was first identified. Parents and doctors may not be aware of this, but. TUESDAY, Aug.

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Drug Discovery World

MARCH 16, 2023

For example, in patients with autoimmune diseases who suffer from uncontrolled T cell activation. Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T cells in mice.

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Drug Discovery World

MAY 20, 2024

GLP-1 receptor agonists like Ozempic (semaglutide) are a class of incretin mimetic medicines for the treatment of type 2 diabetes and obesity. GlobalData’s report predicts that GLP-1 receptor agonists will dominate the metabolic diseases space in the next 10 years.

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Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Biomarker information is also useful for tracking progression of the disease and treatment response. Most drugs do not work in all people.

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Drug Discovery World

JULY 29, 2022

Australian researchers based may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold. She has been fitted with an insulin pump, but her insulin resistance has meant she has spent a lot of time in doctors’ appointments and in hospital.

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Olympian Clinical Research

SEPTEMBER 16, 2022

million Americans were living with Alzheimer’s disease in 2021, according to the Centers for Disease Control and Prevention (CDC). Alzheimer’s disease is the seventh leading cause of death in the United States and is a devastating disease that can rob people of their memories and lives. Eating a Healthy Diet.

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The Pharma Data

AUGUST 22, 2021

In the early days of the COVID-19 pandemic, doctors in Wuhan noticed something surprising. “There’s often a phenomenon that doctors report anecdotally, or that’s mentioned in passing in a particular research paper, and that provides a clue – a hook,” he said. The next challenge was to figure out why.

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Antidote

JANUARY 29, 2024

Not only will patients be able to gain access to potential new treatments, but they will also be directly contributing to research that can save lives — something that Jamie Troil Goldfarb has experienced firsthand. Jamie received a diagnosis of stage IV melanoma in 2011, only 11 weeks after giving birth to her child.

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Olympian Clinical Research

NOVEMBER 9, 2022

Although this disease is estimated to affect less than 50,000 Americans, it may be life-threatening, especially for people who are already in poor health. Therefore, if you or a loved one is dealing with this rare condition, it’s essential to educate yourself about the condition and its potential treatments. Radiation therapy.

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Broad Institute

JUNE 18, 2024

Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment. Funding This work was supported by the Defense Advanced Research Projects Agency, the Centers for Disease Control and Prevention, the Flu Laboratory, and the TED Audacious Project.

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SCIENMAG: Medicine & Health

JUNE 20, 2023

PITTSBURGH, June 20, 2023 – When a patient with chronic kidney disease finally reaches the point that their kidneys fail, doctors have a treatment available: dialysis.

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Drug Target Review

JANUARY 30, 2024

Adenylyl cyclase superactivation induced by long-term treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization. Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons. Br J Pharmacol. 2012;165(6):1704-16. Mol Pharmacol.

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Olympian Clinical Research

JUNE 2, 2021

Despite its prevalence, there’s still a lot that people don’t understand about atopic dermatitis, its symptoms, and the treatment methods available to patients who suffer from the condition. When it comes to treating atopic dermatitis, most available treatments center around symptom mitigation (i.e. What Causes Atopic Dermatitis?

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Drug Discovery World

OCTOBER 18, 2023

Adeno-associated virus (AAV) vector-based gene therapies hold exceptional promise across a range of disease areas. We’re beginning to see their potential come to fruition, with the FDA having approved three treatments as of January 2023 — for retinal dystrophy 1 spinal muscular atrophy, 2 and haemophilia B.

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Alta Sciences

JUNE 27, 2023

Cancer Treatments, Clinical Trials, and the Motivation to Innovate nbartlett Tue, 06/27/2023 - 20:58 Getting to the Heart of Science with Michelle Newby At the heart of science are stories—stories of courage, challenges, successes, lessons, and people. Q: What was your cancer diagnosis and was treatment options were you given?

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Drug Discovery World

NOVEMBER 13, 2023

Nipocalimab, according to Abouzahr, is currently the only FcRn being studied in all three segments of autoantibody-driven disease. She says: “At Janssen, we’re fortunate that we’re building on a leadership that we’ve created over the last couple of decades of treating immune-mediated diseases.

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Conversations in Drug Development Trends

FEBRUARY 22, 2023

Rare Disease Day on February 28th is a chance for rare disease communities to come together as one and join in conversation with stakeholders searching for treatments, raising money to support research, and changing the way healthcare and governments interact with patients. In my case, my daughter Iris has GM1 gangliosidosis.

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National Institute on Drug Abuse: Nora's Blog

FEBRUARY 8, 2023

Pregnant People With Substance Use Disorders Need Treatment, Not Criminalization mfleming Wed, 02/08/2023 - 15:33 Nora's Blog February 15, 2023 Image ©Getty Images/ Caia Image This blog was also published in STAT on February 8, 2023. People seeking treatment for addictions face additional obstacles, especially if they have children.

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The Pharma Data

MAY 14, 2021

Product Name: Hives Urticaria & Angioedema Treatment Protocol | Cure & Relief. Hives Urticaria & Angioedema Treatment Protocol | Cure & Relief is backed with a 60 Day No Questions Asked Money Back Guarantee. They try every known cure, treatment, and medically accepted idea — yet NOTHING works!

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The Pharma Data

MARCH 30, 2021

– Migraine is a debilitating neurological disease affecting 39 million people in the U.S.[2] – Migraine is a debilitating neurological disease affecting 39 million people in the U.S.[2] AbbVie anticipates a regulatory decision in late Q3 2021. 3 Migraine symptoms and severity range widely among individuals.

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The Pharma Data

SEPTEMBER 4, 2020

Dr Moncef Slaoui, the leading doctor involved with Operation Warp Speed, has said it is unlikely a vaccine for the US will be ready by November. . This is in contrast with reports from the Centres of Disease Control and Prevention (CDC). Air Force photo/Senior Airman Areca T.

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On Medicine

FEBRUARY 26, 2023

Behçet’s disease is a rare multisystem vasculitic disorder that can affect any of the blood vessels of the body; signs and symptoms are diverse among individuals and range in severity, but often present as recurrent oral aphthous ulcers, genital ulcers, or as complications involving the eyes.

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The Pharma Data

OCTOBER 23, 2020

23, 2020 — High levels of a protein that lubricates the knee joint may actually be a harbinger of impending joint disease, a surprising animal study suggests. “We know that if a person or animal doesn’t make that protein, they will develop devastating joint disease affecting all the major weight-bearing joints.”

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Drug Discovery World

JANUARY 22, 2024

For the patient as well as for doctors, this means creating more time to make decisions, as the company believes: “Patients – and their quality of life – shouldn’t have to wait for a broken system to provide an answer six months too late.

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KIF1A

JUNE 4, 2024

“We really hope that someday there will be a treatment that can help stop the progression of the symptoms, and give Elena and us more years to enjoy together.” Hundreds of doctor appointments and uncountable exams, second and third opinions, but nothing made sense. The day we received the KAND diagnosis the world stopped.

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Drug Discovery World

SEPTEMBER 5, 2022

The problem is that these tumours respond to treatment initially, but then they come back. What this study shows is that we can actually combine a new target with an old drug to reduce resistance and potentially make the treatment much better.”. One of the challenges we will face is convincing doctors to go back to an old drug.

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Drug Discovery World

JULY 12, 2023

It delivers and administers medicines and medical items to about 200,000 patients with complex conditions including cancer, heart disease, diabetes, dementia and HIV.

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The Pharma Data

JANUARY 20, 2021

Food and Drug Administration (FDA) has accepted the company’s supplemental New Drug Application (sNDA) and granted Priority Review for Esbriet ® (pirfenidone) for the treatment of unclassifiable interstitial lung disease (UILD). About Unclassifiable Interstitial Lung Disease. Since its U.S. About the Pivotal Study. mL, p=0.002).

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Drug Discovery World

JUNE 5, 2023

Showcase agenda Throughout the day, there were a number of presentations on the exhibition floor which provided company updates and showcased a number of exciting results and projects, highlighting both how far we have come in the treatment of disease, as well as how far there is still to go.

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