Drug Discovery World

AUGUST 28, 2024

Pfizer has expanded its strategic partnership with Flagship Pioneering, adding two new research programmes with Flagship-founded Quotient Therapeutics. “With our deep cardiometabolic heritage, we will continue to push the boundaries of research innovation to help address significant gaps in care that remain for these patients.”

Disease 147

Disease Therapies International Drug Development 147

Drug Discovery World

NOVEMBER 1, 2023

The platform is designed to offer pharmaceutical companies and researchers novel and flexible services to grow small-batch crystals of protein-based pharmaceuticals and other key pharmaceutically relevant molecules for research.

Drug Development 147

Drug Development Pharmaceuticals Drugs Pharmaceutical Companies 147

Drug Discovery World

NOVEMBER 29, 2022

Using artificial intelligence, researchers at Chalmers University of Technology, Sweden have succeeded in designing synthetic DNA that controls the cells’ protein production. . The technology can contribute to the development and production of vaccines and drugs for severe diseases much faster and at lower cost. .

DNA 130

DNA Drug Development Research Protein Production 130

Drug Discovery World

JULY 5, 2024

The Division of Clinical Neuroscience at Oslo University Hospital (OUS) and the Swedish drug development company TikoMed have signed a research collaboration agreement focused on amyotrophic lateral sclerosis (ALS).

Drug Research 204

Drug Research Research Hospitals Drugs 204

Fierce BioTech

AUGUST 20, 2024

Alzheimer’s disease research and drug development is evolving at a rapid pace. Decades of research has led to the approval of the first disease-modifying drugs and new pathological discoveries. |

Disease 116

Disease Drug Development Research Drugs 116

Drug Discovery World

SEPTEMBER 16, 2024

Dr Klein shares how Dewpoint applies insights into the subcellular organisation of biochemical processes into membrane-less compartments to discover novel drug targets and revolutionary drugs for diseases with high unmet need, including amyotrophic lateral sclerosis (ALS) and Rett Syndrome. Register today!

Research 147

Research Drugs Science Disease 147

Drug Discovery World

JUNE 2, 2023

Download this exclusive eBook to learn more about: The latest advancements in artificial intelligence How machine learning is being used across cancer research Why AI is critical to solving challenges in drug discovery How AI can improve drug development for rare diseases Access the eBook here.

Drug Development 130

Drug Development Drugs Disease Research 130

Drug Discovery World

DECEMBER 6, 2022

As a result of clear US Food and Drug Administration (FDA) guidelines, the leading vaccine development programmes for Covid-19 were all remarkably similar. One way that NPIs research could introduce greater objectivity is by using quasi-experimental methods. Indeed, few randomised trials of NPIs have been undertaken.

Drug Development 246

Drug Development Vaccine Drugs Pharmaceuticals 246

Drug Discovery World

NOVEMBER 29, 2023

Researchers have created a mathematical model that can accurately depict Alzheimer’s disease progression in individual patients, paving the way for personalised treatment and faster development of therapies.

Drug Development 130

Drug Development Pharmaceutical Companies Drugs FDA Approval 130

Drug Discovery World

SEPTEMBER 11, 2024

Dr Klein shares how Dewpoint applies insights into the subcellular organisation of biochemical processes into membrane-less compartments to discover novel drug targets and revolutionary drugs for diseases with high unmet need, including amyotrophic lateral sclerosis (ALS) and Rett Syndrome. Register today!

Research 130

Research Drugs Science Disease 130

Drug Discovery World

JUNE 5, 2024

million to fund a new two-year collaborative partnership with King’s College London (KCL) to validate a portfolio of human genetic driven therapeutic targets for motor neuron disease (MND). Historical pipeline data suggests that drug targets with human genetic disease association are twice as likely to lead to approved drugs.

Bioinformatics 173

Bioinformatics Research Drugs Clinical Trials 173

Drug Discovery World

SEPTEMBER 21, 2023

A research team from VIB-KU Leuven and the UK Dementia Research Institute has discovered how neurons die in Alzheimer’s disease, opening new pathways for potential future treatments. The research team was also able to prevent the death of neurons, rescuing them in the process.

Disease 263

Disease RNA Research Science 263

Drug Discovery World

FEBRUARY 2, 2024

Head of clinical trials at the University College London (UCL) Dementia Research Centre, Dr Cath Mummery, has been announced as the Director of a new network of dementia trial sites across the country. million of new funding to improve access to clinical trials and help accelerate the development of new treatments.

Research 250

Research Clinical Trials Trials Science 250

Drug Discovery World

JUNE 30, 2023

Research tools, safety testing and regenerative medicines – these endless stem cell applications are powering precision, speed, and new modalities in drug development. Stem cells for use in drug discovery Stem cells are fast becoming an invaluable tool in the drug discovery process.

Drug Development 130

Drug Development Drugs Disease Assay Development 130

Drug Discovery World

MAY 13, 2024

The University of Texas MD Anderson Cancer Center has been awarded $20 million to strengthen neurodegeneration research. The consortium was established to gain a deeper understanding of neurodegenerative disease biology and translate those findings into effective therapeutic interventions. Yet, we still have more work to do.

Research 130

Research Disease Drug Development Therapies 130

Drug Discovery World

APRIL 14, 2023

Oliver Schon, PhD, is VP Research & Development at BiVictriX Therapeutics, a UK-based emerging drug discovery and development company generating a pioneering first-in-class next-generation ADC anti-cancer therapeutics which exhibit superior selectivity towards cancer.

Drug Development 130

Drug Development Drugs Clinical Trials Therapies 130

Drug Discovery World

MAY 9, 2023

Jantzen Sperry , PhD, Director of Scientific Operations at Certis Oncology looks at how the adoption of orthotopic PDX models can elevate the impact of cancer research and improve translation in oncology drug development. Fewer than 5% of oncology drugs that enter clinical trials in the US receive US FDA approval.

Drug Development 130

Drug Development Clinical Trials Animal Testing Cell Based Assays 130

Drug Discovery World

FEBRUARY 13, 2023

Cell and gene therapies (CGT) are transforming the way diseases are treated. As research progresses it is hoped that cell and gene therapies will offer innovation for the future. The post Webinar: Opportunities for CGT in drug development appeared first on Drug Discovery World (DDW).

Drug Development 130

Drug Development Therapies Drugs Marketing 130

Drug Discovery World

JUNE 14, 2024

Flagship Pioneering and ProFound Therapeutics have announced a collaboration to conduct foundational research to identify potential next-generation first-in-class therapies for the treatment of obesity. Charlotte Allerton, Head of Discovery and Early Development, Pfizer, said: “With obesity expected to impact 1.9

Research 147

Research Drugs Therapies Drug Development 147

Drug Discovery World

APRIL 20, 2023

Dr Paula Moran, Dr Kiri Granger, Dr J Mark Treherne , and Dr Jenny Barnett explore the effects of long Covid-19 symptoms and what the opportunities are for drug developers working to treat post-Covid-19 cognitive impairment. Alzheimer’s disease), or by initiating a new one. depression).

Drug Development 246

Drug Development Clinical Trials Drugs Virus 246

Drug Discovery World

JUNE 2, 2023

Download this exclusive eBook to learn more about: The latest advancements in artificial intelligence How machine learning is being used across cancer research Why AI is critical to solving challenges in drug discovery How AI can improve drug development for rare diseases The post AI and drug development: Using AI and machine learning to expedite drug (..)

Drug Development 130

Drug Development Drugs Disease Research 130

DrugBank

AUGUST 15, 2024

Drug development is challenging, including not only the complexities of biomolecular drug mechanisms but also the convolutions of regulatory pathways and commercialization strategies. This includes funding large-scale clinical trials and establishing robust manufacturing/distribution networks.

Drug Development 82

Drug Development Clinical Trials Drugs Therapies 82

Drug Discovery World

OCTOBER 10, 2023

The National Institutes of Health has awarded the first phase of a roughly $40m grant to Yale University to advance a novel CRISPR-based gene-editing delivery platform for the targeted treatment of neurogenetic diseases. The two diseases being targeted in the project are Angelman syndrome and H1-4 (HIST1H1E) syndrome.

Drug Development 130

Drug Development Clinical Trials Engineering Drugs 130

Drug Discovery World

JULY 19, 2024

TPD is a rapidly emerging field in drug development, exploiting a cell’s own destruction machinery to tackle disease-causing proteins that have historically been highly challenging to target with conventional therapies.

Targeted Protein Degradation 130

Targeted Protein Degradation Small Molecule Research Government 130

Drug Discovery World

DECEMBER 5, 2022

A new partnership between industry and three rare disease foundations has formed with the goal of accelerating the development of precision drugs to treat rare neurodevelopmental disorders. . Understanding rare diseases remains a significant challenge. Understanding rare diseases remains a significant challenge.

Drug Development 130

Drug Development Clinical Trials Drugs Disease 130

Drug Discovery World

NOVEMBER 29, 2023

DDW’s Megan Thomas speaks to Jennifer Cann, Director of Pathology at Virscio, a company solving human health challenges through biomedical research. MT: Can you provide a top line summary of your research? The post Meet the Researcher: Jennifer Cann, Director of Pathology, Virscio appeared first on Drug Discovery World (DDW).

Research 173

Research Clinical Trials Trials Drug Development 173

Drug Discovery World

JANUARY 24, 2023

DMD and FA are rare, degenerative, genetic diseases that affect movement and eventually lead to paralysis. This is particularly important for rare diseases where it can be hard to identify suitable patients. In the FA study, teams worked with patients to identify key movement patterns and predict genetic markers of disease.

Drug Development 130

Drug Development Clinical Trials Trials Disease 130

Drug Discovery World

OCTOBER 9, 2023

Second is the incomplete understanding of the drivers and nature of the disease: long Covid is a complex set of symptoms and manifestations and understanding it is important. This is a new dynamic and efforts on research, clinical trials regulatory, and financial support are required.

Drug Development 147

Drug Development Clinical Trials Virus Drugs 147

Drug Discovery World

APRIL 29, 2024

Dr Currien MacDonald, Medical Chair Director at WCG, discusses the challenges and opportunities presented by cannabis research. Research support Support for researching cannabidiol is expanding. More importantly, cannabis research received additional governmental support for continued investigation at the end of 2022 with H.R.8454,

Research 147

Research FDA Drug Development Production 147

Drug Target Review

AUGUST 28, 2024

What are the main challenges currently faced in the treatment of chronic liver diseases, and how does Resolution Therapeutics aim to address these challenges? Once a patient develops advanced cirrhosis/end-stage liver disease there are no specific therapies to significantly avoid major decompensations and death in the next few years.

Therapies 114

Therapies Disease Engineering Medical Schools 114

Drug Discovery World

JULY 25, 2023

Justin Hay , Senior Director, Amy Cheung Senior Director of Integrated Drug Development, and Patrick Loebs Director, at Certara, examine recent changes in paediatric guidelines and how they affect drug development projects. The guidance mentions PBPK four times regarding renal function and DDIs.

Drug Development 130

Drug Development Clinical Pharmacology Pharmacokinetics Drugs 130

Drug Discovery World

NOVEMBER 8, 2023

Over 19 million 1 hearts succumb to cardiovascular disease yearly, while around 10 million 2 lives are claimed by cancer every year. By swiftly sifting through complex datasets, AI algorithms can identify patterns, extract valuable insights, and uncover subtle correlations that might elude human researchers.

Clinical Trials 182

Clinical Trials Trials Disease Medical Schools 182

Broad Institute

SEPTEMBER 6, 2023

This collaboration has the potential not only to accelerate our understanding of the diseases, but also potentially enable scientific advancements in disease-modifying interventions — a true game changer in addressing cardiometabolic diseases.” The collaboration will focus on advancing three programs over the next three years.

Disease 136

Disease Research Therapies Treatment 136

Drug Discovery World

OCTOBER 17, 2023

The DDW Turning Science into Business Summit, ‘ Cancer research opportunities and advances ’ will feature experts and thought leaders in cancer research, precision medicine and immunotherapy. Muaiad Kittaneh Dreps and Kittaneh will also explore the importance of collaboration and data sharing in antibody drug development.

Marketing 130

Marketing Research Clinical Trials Science 130

Drug Discovery World

MAY 25, 2023

Following the Scottish Research and Drug Development Forum meeting, DDW’s Diana Spencer provides a snapshot of drug discovery in Scotland. Introduction to the CRUK Beatson Institute The first speaker was Professor Owen Sansom, Director of the Cancer Research UK Beatson Institute, who gave two presentations.

Research 130

Research Drugs Virus Disease 130

Drug Discovery World

JANUARY 30, 2023

Cell and gene therapies (CGT) are transforming the way diseases are treated. As research progresses it is hoped that cell and gene therapies will offer innovation for the future. The post Webinar: Transforming disease treatment with CGT appeared first on Drug Discovery World (DDW).

Disease 130

Disease Treatment Therapies Drug Development 130

Drug Discovery World

SEPTEMBER 8, 2022

New norms set during the COVID-19 pandemic have only fueled the industry’s expectations of accelerated drug development,” said James Matcham, Executive Strategic Consultant, Cytel, Australia. . The post Cytel hopes to accelerate drug development in APAC region appeared first on Drug Discovery World (DDW).

Drug Development 130

Drug Development Clinical Trials Drugs Trials 130