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€12 million raised for extracellular protein degradation research

Drug Discovery World

Biotechnology company Draupnir Bio has received equity investments totalling €12 million to support the company’s work in the field of targeted protein degradation (TPD).

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Untapping the potential of targeted protein degradation with proteomics

Drug Discovery World

Professor Henrik Daub , Founder and CSO, NEOsphere Biotechnologies looks at the advancements taking place in proteomics and how targeted protein degradation represents a promising approach for developing new treatments for life-threatening diseases. PROTAC targeted protein degraders: the past is prologue.

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Molecular glues: new solutions for undruggable proteins | BMG LABTECH

BMG Labtech

Promising future Molecular glues offer exciting opportunities for targeted protein degradation and new ways to reach some of the estimated 85% of undruggable targets in the proteome. Conventional drug development has often focused on finding small molecules that fit the active site of a protein.

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Industry collaborations advancing drug discovery

Drug Discovery World

Strategic research partnerships bring together knowledge, expertise and technologies, allowing advancements in our understanding of diseases and therapeutics that would not be possible in isolation. The collaboration seeks to validate novel drug targets that are causally linked to clinical endpoints in Huntington’s disease.

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The DDW Podcast: 2023 in review

Drug Discovery World

Fricker was a founder of Canadian biopharma company AnorMED, acquired by Genzyme, and awarded the Queen’s Award for Technology for his participation in the development of the anticancer drug Paraplatin. He speaks about this drug discovery journey here. Listen here. Listen here. Listen here. This episode is available here.

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Reflecting on BioTrinity 2023  

Drug Discovery World

However, she also presented thoughts in a technical update, Targeted Protein Degradation – Progress, Direction and Prospects. In its pipeline, Imophoron is working on ADDomer based vaccines for three diseases, respiratory syncytial virus (RSV), Covid-19 and Chikungunya.

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European drug discovery and development: success stories

Drug Discovery World

This growth is due to factors including a rise in speciality medicines, an increase in lifestyle-driven diseases and a growing population 1. With key players including AstraZeneca, Bayer, Novartis and Pfizer pushing the boundaries of drug development, the reason behind this growth is evident. Volume 23 – Issue 4, Fall 2022.