Drug Discovery World

MAY 21, 2024

Modern experimental procedures, such as immunisation, B-cell screening, and synthetic library generation, have been pivotal in developing approximately 80 FDA-approved antibody therapeutics. These targets, along with many others, are universally deemed as ‘difficult-to-drug’ targets.

FDA Approval 147

FDA Approval FDA Disease Treatment 147

Drug Discovery World

NOVEMBER 29, 2023

Researchers have created a mathematical model that can accurately depict Alzheimer’s disease progression in individual patients, paving the way for personalised treatment and faster development of therapies. The post Mathematical model can speed up Alzheimer’s drug development appeared first on Drug Discovery World (DDW).

Drug Development 130

Drug Development Pharmaceutical Companies Drugs FDA Approval 130

Drug Discovery World

MAY 3, 2023

Official comments “Measuring endothelial dysfunction with the EndoPAT technology in drug trials is a cost-effective and robust method for early documentation of proof-of-concept in pulmonary, renal and vascular diseases” says Elin Rosendahl, VP Clinical Operations, Vicore Pharma.

FDA Approval 130

FDA Approval Trials Pharmaceutical Companies Disease 130

Advarra

AUGUST 16, 2022

A rare, or orphan, disease by definition affects a small percentage of the population — fewer than 200,000 people in the U.S. But the numbers add up, and taken together, rare diseases impact an estimated 30 million Americans. Before 1983, only 38 orphan drugs had received U.S. Food and Drug Administration (FDA) approval.

Disease 52

Disease Clinical Trials FDA Approval FDA 52

Drug Discovery World

MARCH 7, 2023

Here at FAB our proprietary approach aims to overcome this fundamental challenge to human health as we work to discover and develop new drugs for age-associated diseases.” She founded Neuroute in 2019, with the aim of empowering patients from diverse backgrounds to participate in drug trials.

International 246

International Science Pharmaceuticals DNA 246

Drug Discovery World

JANUARY 17, 2024

Liquid biopsies have specific advantages over the current gold standard for tumour characterisation, tissue biopsies: not only are they less invasive and less costly, they provide results faster, are more suitable for longitudinal disease monitoring and less likely to cause harmful side effects.

DNA 147

DNA Clinical Trials RNA Treatment 147

Drug Target Review

SEPTEMBER 19, 2023

The chips can be modelled with primary cells, IPS derived stem cells or patient derived cells and potentiates to unlock molecular mechanisms that drive the disease pathophysiology, holding a greater promise. The first successful chip adaptation to a lung model was first described in 2010 by Donald Ingber, a bioengineer at Wyss institute.

Animal Testing 98

Animal Testing Clinical Trials Pharmaceutical Companies FDA 98