Remove Disease Remove Fragment Screening Remove Pharmacokinetics
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SARS-CoV-2 Protease Inhibitors: An Attractive Approach for Treating COVID-19

PerkinElmer

There is therefore an urgent need for the development of effective antivirals to complement vaccination efforts and prevent more severe disease, hospitalization, and death. The second virtual screen focused on optimization of a hit from a previous crystallographic fragment screen.

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SARS-CoV-2 main protease. Crowdsourcing, peptidomimetics and fragments

Molecular Design

While I’m not particularly keen on the use of the term ‘open source’ in this context, I have absolutely no quibble with the goal of seeking cures and treatments for diseases that are ignored by commercial drug discovery organizations.