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Using next-gen CRISPR tool, scientists create unprecedented molecular map of human immune response

Science Daily: Pharmacology News

In a study of historic scale, scientists have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

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Medicago Says COVID-19 Vaccine Candidate Triggers Promising Immune Response | 2020-11-10

The Pharma Data

Canadian biopharmaceutical company Medicago has announced that its investigational COVID-19 vaccine generated “significant antibody and cellular immune responses” after two doses in all subjects in an early-stage clinical trial. Based on the promising phase 1 data, the company plans to proceed with a phase 2/3 clinical trial. “We

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The Vaccine Development Landscape and Its Associated Challenges

DrugBank

Vaccines have consistently demonstrated their efficacy in protecting people from infectious diseases. This led to the eradication of smallpox and polio – two debilitating diseases that historically caused global epidemics. Adjuvants are substances added to vaccines to enhance the immune response.

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Novavax Announces Agreement with Government of New Zealand for 10.7 Million Doses of COVID-19 VaccineAdvance purchase agreement signed for NVX-CoV2373, Novavax’ adjuvanted protein vaccine candidate

The Pharma Data

Nasdaq: NVAX), a late-stage biotechnology company developing next-generation vaccines for serious infectious diseases, today announced an Advance Purchase Agreement with the government of New Zealand for the purchase of 10.7 GAITHERSBURG, Md., 16, 2020 (GLOBE NEWSWIRE) — Novavax , Inc. About Novavax. Novavax, Inc.?(Nasdaq:

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Broad Discovery Series: Introducing the immune system, and expanding its cancer-fighting potential

Broad Institute

Studies of cancer immunotherapy have largely focused on T cells, but the Bod lab seeks to understand whether the immune system's antibody-producing B cells can also be leveraged for cancer treatment. Learn more about the Broad Discovery Series.

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Merck to Focus on COVID-19 Therapeutics After Scrapping Its Coronavirus Vaccine Programs | 2021-01-25

The Pharma Data

In a surprise move, Merck announced that it is giving up on its two coronavirus vaccine candidates after seeing a subpar immune response and shifting its focus to a pair of investigational coronavirus treatments. government for up to 100,000 doses ( DID, Dec. 28, 2020 ). and around the globe.

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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and Infectious Diseases in Frontiers in Science. COVID clearly caught us off guard.

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