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Successful clinical trial for re-engineered Covid vaccine 

Drug Discovery World

The University of Queensland’s re-engineered clamp platform has produced a vaccine that is equally safe and virus-neutralising as an approved Covid vaccine considered among the best in its class. million to continue development for use in the global response to future disease outbreaks.

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Researchers have cracked the cellular code on protein folding, offering hope for new therapeutic avenues for many diseases

Science Daily: Pharmacology News

While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins.

Disease 90
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How structural biology is informing vaccine design

Drug Discovery World

MA: Regarding vaccine development specifically, and the role my team plays in the development of cryogenic electron microscopy (cryo-EM) technology, we see the study and dissemination of virus structures, and the proteins that comprise them, as vital to vaccine design. MA: Respiratory viruses represent a diverse group of pathogens.

Vaccine 147
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New UK partnership to accelerate mRNA research

Drug Discovery World

It is hoped that a new partnership between the UK government and BioNTech will help accelerate clinical trials of personalised immunotherapies for cancer and infectious disease vaccines. . The agreement means cancer patients will get early access to trials exploring personalised mRNA therapies, like cancer vaccines. .

Research 130
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Long Covid: A call to action for drug developers

Drug Discovery World

highlight the impact of viral infection on several facets of this central mitochondrial organelle, including bioenergetics, metabolism, inflammation, and oxidative stress, with downregulation of these processes across several organ systems both in the presence of the virus (and correlated with severity) and after the virus is not detected.

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Funding to advance gene therapy for cerebrotendinous xanthomatosis treatment 

Drug Discovery World

These deposits can cause progressive damage to the brain and other areas of the body. Disease symptomatology is characterised by chronic diarrhea during infancy and cataracts in late childhood. At present there is no cure for CTX, only treatment to slow disease progression. Vivet Therapeutics has received €4.9

Therapies 130
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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132