Drugs.com

NOVEMBER 20, 2023

20 , 2023 -- Salmonella-tainted cantaloupe has landed 17 people in the hospital, warns the U.S. Centers for Disease Control and Prevention. MONDAY, Nov. At least 43 people across 15 states and Canada have been sickened in the outbreak, which are.

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Hospitals Disease 105

Drugs.com

AUGUST 16, 2023

16, 2023 -- New hospitalizations for Americans with severe COVID are climbing once again. The number of patients being admitted to hospitals has grown for each of the past four weeks, U.S. Centers for Disease Control and Prevention. WEDNESDAY, Aug.

Hospitals 98

Hospitals Disease 98

SCIENMAG: Medicine & Health

JULY 14, 2023

The range of COVID-19 symptoms varies—some feel a mild cold, others are hospitalized, while others perish. Many studies have linked the severity of COVID-19 symptoms with an individual’s biological factors, but less is known about the impact of non-biological factors, such as the environment in which people live.

Hospitals 78

Hospitals Disease 78

Drug Discovery World

AUGUST 11, 2023

Liverpool School of Tropical Medicine (LSTM) and LifeArc are partnering to launch a new Translational Development Fund to help tackle infectious diseases. million into the fund, which will support the progression of new technologies and treatments for emerging viral threats and neglected tropical diseases. LifeArc will invest £2.7 ($3.4)

Disease 130

Disease Therapies Research Hospitals 130

Broad Institute

APRIL 2, 2024

Scientists link certain gut bacteria to lower heart disease risk By Allessandra DiCorato April 2, 2024 Breadcrumb Home Scientists link certain gut bacteria to lower heart disease risk Study finds several species of cholesterol-metabolizing bacteria in people with lower cholesterol levels. Online April 2, 2024. DOI:10.1016/j.cell.2024.03.014.

Disease 145

Disease Medical Schools Hospitals DNA 145

Drugs.com

JUNE 27, 2023

hospitals, and a coalition of medical groups has now issued a set of updated recommendations to protect patients. TUESDAY, June 27, 2023 -- “Superbug” infections are increasing in U.S. These guidelines are meant to prevent the spread of.

Hospitals 73

Hospitals Disease 73

Drug Discovery World

OCTOBER 10, 2022

A new clinical trial, led by the University of Glasgow and NHS Greater Glasgow and Clyde (NHSGGC), hopes to improve treatment options for patients with Crohn’s disease. . Crohn’s disease is a chronic condition which currently affects more than 115,000 people in the UK and causes inflammation of the lining of the digestive system.

Disease 130

Disease Treatment Hospitals Therapies 130

Drug Discovery World

NOVEMBER 2, 2022

Co-developed by researchers and engineers at the Department of Biology, University of Oxford and Boston Children’s Hospital, USA, Global.health enables access to real-time, anonymised health data on infectious disease outbreaks, for the first time.

Disease 130

Disease International Engineering Hospitals 130

Broad Institute

MARCH 19, 2024

Researchers roll out a more accurate way to estimate genetic risks of disease By Claire Hendershot March 19, 2024 Breadcrumb Home Researchers roll out a more accurate way to estimate genetic risks of disease Two new approaches for generating polygenic scores demonstrate that compiled data improves score accuracy.

Disease 136

Disease Research Packaging Hospitals 136

Drug Discovery World

OCTOBER 10, 2023

Rejuvenate Biomed, a clinical-stage company advancing therapeutics to delay the onset of age-related diseases, has completed a six-week clinical proof-of-mechanism study with lead candidate RJx-01 for the treatment of sarcopenia.

Disease 130

Disease Pharmacokinetics Treatment Hospitals 130

Drugs.com

NOVEMBER 3, 2023

Centers for Disease Control and Prevention are expected to approve new draft guidelines for hospital infection control this week, the first update since 2007. FRIDAY, Nov. 3, 2023 -- Advisors to the U.S. But healthcare workers worry whether the.

Hospitals 73

Hospitals Disease 73

Drug Discovery World

JUNE 19, 2024

These dramatic improvements – if confirmed by further studies – may eventually provide renewed hope for a much-needed paradigm shift in the treatment of debilitating autoimmune diseases.” KYV-101 is a product candidate for use in B cell-driven autoimmune diseases.

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Therapies Disease Hospitals Treatment 246

Drug Discovery World

APRIL 14, 2023

million to fund its development of the world’s first treatment for TUBB4A-related leukodystrophy, a rare, incurable and deadly disease. The post ‘Virtual’ biotech targets R&D funding on rare disease therapy appeared first on Drug Discovery World (DDW). UK biotech firm SynaptixBio has secured £13.2

Disease 130

Disease Therapies Clinical Trials Treatment 130

Broad Institute

OCTOBER 23, 2023

The team aims to uncover how genetics and lifestyle affect cardiometabolic disease risk in South Asian populations and how to potentially decrease that risk, including through the development of new drugs and lifestyle modifications. “A

Disease 145

Disease Research Hospitals DNA 145

Drug Discovery World

DECEMBER 11, 2023

The US Food and Drug Administration (FDA) has approved the first cell-based gene therapies for the treatment of sickle cell disease (SCD), Casgevy and Lyfgenia. Diana Spencer, Senior Digital Content Editor, DDW The post FDA approves first gene therapies for sickle cell disease (with a warning) appeared first on Drug Discovery World (DDW).

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FDA Approval Therapies FDA Disease 130

SCIENMAG: Medicine & Health

FEBRUARY 13, 2024

CLEVELAND — A recent study from researchers at University Hospitals (UH) Connor Whole Health and UH Rainbow Babies & Children’s Hospital describes a quality improvement project where pain screening procedures were embedded within an outpatient pediatric sickle cell disease (SCD) clinic.

Disease 77

Disease Hospitals Research 77

Drug Target Review

DECEMBER 29, 2023

Scientists in China have published their findings 1 regarding novel biomarkers, which they hope will benefit patients by identifying the disease at an earlier stage. Diabetic kidney disease DKD is a major microvascular complication of type 2 diabetes mellitus (T2DM). References Du S, Zhai L, Ye S, et al. Science China Life Sciences.

Disease 126

Disease Science Hospitals Treatment 126

Drug Discovery World

JANUARY 30, 2023

There is a significant need for a treatment specifically developed to help manage the progression of this disease. We in the FOP community have been waiting a long time for innovations to treat this disabling disease.” “We in the FOP community have been waiting a long time for innovations to treat this disabling disease.”

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Treatment Disease Clinical Trials Trials 130

SCIENMAG: Medicine & Health

AUGUST 23, 2023

Bodo Beck first saw the three children of a family who had fled Syria sitting in his consultation room at University Hospital Cologne, the human geneticist was surprised. His genetic analysis diagnosed Bartter syndrome type 3, but never before had he seen such severe joint changes in patients with this rare disease.

Disease 89

Disease Hospitals 89

Broad Institute

FEBRUARY 7, 2024

However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. The team found that a key biological mechanism involved in a rare vascular disease may influence CAD risk.

Disease 106

Disease Hospitals Medical Schools Regulations 106

Drug Discovery World

JULY 3, 2024

In March 2022, a clinical research team at the Hospital for Sick Children (SickKids) in Toronto, Canada, administered a first single-patient gene therapy to patient Michael Pirovolakis less than three years after his initial diagnosis. Approximately 80 children around the world are affected by the condition.

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Therapies Clinical Trials Virus Disease 147

SCIENMAG: Medicine & Health

JUNE 12, 2023

BOSTON – A new study led by investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, offers an explanation for why light-to-moderate alcohol consumption may be associated with lower risk of heart disease.

Hospitals 91

Hospitals Research Disease 91

Drug Discovery World

AUGUST 28, 2023

DDW’s Diana Spencer speaks to Peter Hamley , Chief Scientific Officer of Samsara Therapeutics, to understand the role autophagy plays in neurodegenerative diseases and how boosting this process could increase healthspan. But it’s now known that if it stops working this can lead to many different diseases. What is autophagy?

Disease 130

Disease Science Clinical Trials Therapies 130

Broad Institute

SEPTEMBER 28, 2023

By Allessandra DiCorato September 28, 2023 Credit: Strittmatter Laboratory, Yale University Amyloid beta clusters (red) builds up among neurons (green) in a mouse model of Alzheimer’s disease. The scientists identified a suite of changes in cells unique to the early stages of Alzheimer’s, including some not seen before in animal studies.

Disease 144

Disease Medical Schools Hospitals Research 144

SCIENMAG: Medicine & Health

JULY 24, 2023

Centers for Disease Control and Prevention’s VISION Network, has determined both the number of adults needed to be vaccinated to prevent one COVID-19 associated hospitalization […] An analysis of real-world data from more than 1.2

Hospitals 84

Hospitals Vaccine Disease 84

Broad Institute

JANUARY 25, 2024

They found significant associations between the thinning of different retinal layers and increased risk of developing ocular, cardiac, pulmonary, metabolic, and neuropsychiatric diseases and identified genes that are associated with retinal layer thickness. Their findings are published in Science Translational Medicine. “We

Disease 125

Disease Research Medical Schools Science 125

Drug Discovery World

JUNE 26, 2024

Scientists at the University of Bristol have uncovered a new disease driving mechanism which they are aiming to target to help treat the development of atherosclerotic plaques. This unique award will allow us to develop a therapeutic to target this novel non-coding RNA, and validate its use in patients with heart disease.”

Treatment 147

Treatment Research Medical Schools RNA 147

Broad Institute

DECEMBER 7, 2023

A team led by investigators at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard recently developed a strategy for inferring which of these phases is present for rare variant pairs within genes. Tags: Medical and Population Genetics Program Rare Disease Clinical genomics Nature Genetics.

Disease 105

Disease Hospitals International Research 105

Drug Discovery World

FEBRUARY 28, 2023

As we turn our focus to new potential applications and disease areas for the platform, scientists and companies must consider the potential life-saving impact on rare, inherited diseases, says Archana Gupta , PhD, staff scientist in genetic sciences at Thermo Fisher Scientific.

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Disease Treatment Vaccine DNA 130

Drug Target Review

JULY 13, 2023

In this article, we will delve into the world of condensate biology and explore the groundbreaking research projects undertaken to discover the potential they hold for diseases such as amyotrophic lateral sclerosis ( ALS ) and colorectal cancer. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Medical Schools 98

Broad Institute

JULY 6, 2023

The accuracy of these scores has improved for some diseases and groups of people, but they continue to fall short for those of non-European ancestry, mainly because the genetic datasets used to calculate these scores have largely come from people of European ancestry.

Disease 97

Disease DNA Hospitals Medical Schools 97

SCIENMAG: Medicine & Health

JANUARY 26, 2024

Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People’s Hospital). Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People’s Hospital). Credit: ©Science China Press This study is led by Prof.

Disease 76

Disease Hospitals Science 76

Broad Institute

JUNE 25, 2024

Results of the study — which represents a collaboration across Brigham and Women’s Hospital, the Broad Institute of MIT and Harvard, and Harvard T.H. Co-first authors on the paper are Zhendong Mei of and Women’s Hospital and Broad, and Fenglei Wang of Harvard Chan School and Broad.

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Virus Hospitals Disease Nurses 135

Drug Discovery World

JUNE 25, 2024

The paper was co-authored by analytics company Phesi and Dr Yi-Bin Chen, Director for the Blood and Marrow Transplant Program at Massachusetts General Hospital. Phesi created a digital twin for chronic graft versus host disease (cGvHD) in the primary treatment setting.

Clinical Trials 147

Clinical Trials Trials Hospitals Clinical Research 147

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. This New Alternative Model (NAM) provides a platform for High-Content Screening through disease modeling through the transplantation of primary patient tumors into immunocompromised lines.

Disease 59

Disease Medical Schools Pharma Companies Clinical Trials 59

Drugs.com

JANUARY 17, 2024

WEDNESDAY, Jan 17, 2024 -- Palliative care is meant to ease suffering at any stage of disease, but too often many patients wait too long for this type of care to be ordered. Now, researchers at the University of Pennsylvania may have come up with a.

Hospitals 85

Hospitals Disease Research 85

SCIENMAG: Medicine & Health

JULY 28, 2023

Lurie Children’s Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn’s disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

Disease 53

Disease Hospitals Research 53