Drug Hunter

AUGUST 21, 2023

Obtaining adequate drug exposure in the brain is key to treating CNS diseases effectively. Prodrugs Remain in “Proof-of-Concept” Stages Prodrug strategies for CNS deliver have also been applied with varying success , with the most famous example being L-Dopa for Parkinson’s disease. Figure 18.

Drugs 206

Drugs Disease Targeted Protein Degradation Screening Hits 206

The Pharma Data

NOVEMBER 19, 2020

Gelbman most recently served as the founding CEO of FDNA, a digital health startup that develops advanced AI tools to help diagnose patients with rare diseases. Patel currently serves as the director of Infectious Diseases Research Laboratory at the Mayo Clinic, as well as co-director of the clinical Bacteriology Laboratory.

Laboratories 52

Laboratories Research Laboratories Science Organic Chemistry 52

PLOS: DNA Science

APRIL 17, 2025

Next month, families affected by the rare genetic disease metachromatic leukodystrophy (MLD) will meet in Washington. Because Calliope Joy didn’t have an older sibling with the disease, her initial symptoms were confusing. It is jargony enough to reawaken nightmares of taking organic chemistry.

Therapies 96

Therapies Bioethics DNA Organic Chemistry 96