Remove Disease Remove Immune Response Remove Medical Schools
article thumbnail

New “dictionary” of immune responses reveals far more complexity in the immune system than previously thought

Broad Institute

The immune system can carry out many biological processes, from killing viruses to fighting cancer, thanks in large part to approximately 100 key cell-signaling proteins called cytokines, which instruct immune cells what to do. The reference, called the Immune Dictionary , appears today in Nature.

article thumbnail

Revolutionary nanoparticles enable gene-editing in lungs

Drug Target Review

Scientists from the Massachusetts Institute of Technology (MIT) and the University of Massachusetts Medical School (UMass), US, have collaborated to create a novel type of nanoparticle that can deliver messenger RNA that encodes for beneficial proteins to the lungs.

RNA 98
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Not all neoantigens are created equal

Drug Target Review

These neoantigens are identified by T cells of the immune system as foreign proteins and thus trigger an immune response. Neoantigens are recognised as non-self and trigger an immune response. Patients with high numbers of clonal neoantigens show improved disease-free survival.

article thumbnail

Broad Discovery Series: Introducing the immune system, and expanding its cancer-fighting potential

Broad Institute

Lloyd Bod is an associate member of Broad, a principal investigator in the Krantz Family Center for Cancer Research at Massachusetts General Hospital, and an assistant professor of medicine at Harvard Medical School. Learn more about the Broad Discovery Series.

article thumbnail

Researchers decipher how a gut bacterium influences immunity

Broad Institute

Researchers decipher how a gut bacterium influences immunity By Corie Lok July 26, 2022 Breadcrumb Home News Researchers decipher how a gut bacterium influences immunity Study finds a molecule made by the bacterium that helps moderate immune responses. It gets its name from the intestinal mucus it breaks down.

article thumbnail

Advances in the Battle Against Autoimmune Disease

The Pharma Data

A healthy immune system defends the body against disease and other conditions. However, if the immune system malfunctions, it can attack healthy cells, tissues and organs. Autoimmune disease impacts different parts of the body, weakening functionality. Autoimmune diseases affect more than 24 million people in the U.S.

Disease 52
article thumbnail

T-cell receptors offer window to the cell for a new class of cancer therapeutics

Drug Target Review

This produces a great advantage in infectious disease, as it becomes difficult for a virus to adapt and spread from person to person, because each person’s HLA array is genetically distinct. Therefore, therapeutically useful tumour antigens represent a tiny fraction of the genes expressed by a tumour cell.