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Discovery of 'new rules of the immune system' could improve treatment of inflammatory diseases, say scientists

Science Daily: Pharmacology News

Tests, in mice, of a drug developed by the researchers showed that regulatory T cells can be attracted to specific body parts, boosted in number, and activated to suppress immune response and rebuild tissue.

Treatment 336
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Scientists discover a cause of lupus and a possible way to reverse it

Science Daily: Pharmacology News

Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse the disease.

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Using next-gen CRISPR tool, scientists create unprecedented molecular map of human immune response

Science Daily: Pharmacology News

Their findings uncover detailed information that could help overcome the limitations of today's immunotherapies and identify new drug targets for a wide range of diseases, including autoimmune diseases and cancer.

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New “dictionary” of immune responses reveals far more complexity in the immune system than previously thought

Broad Institute

The immune system can carry out many biological processes, from killing viruses to fighting cancer, thanks in large part to approximately 100 key cell-signaling proteins called cytokines, which instruct immune cells what to do. The reference, called the Immune Dictionary , appears today in Nature.

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Western diet causes inflammation, traditional African food protects

Science Daily: Pharmacology News

A switch of just two weeks from a traditional African diet to a Western diet causes inflammation, reduces the immune response to pathogens, and activates processes associated with lifestyle diseases. This study highlights the significant impact of diet on the immune system and metabolism.

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Beneficial gut microbe has surprising metabolic capabilities

Science Daily: Pharmacology News

A strain of the bacterium harbored in the children's gut microbial communities possessed a previously unknown gene capable of producing and metabolizing key molecules involved in regulating many important functions ranging from appetite, immune responses, neuronal function, and the ability of pathogenic bacteria to produce disease.

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Key improvements to Parkinson's disease cell therapies

Science Daily: Pharmacology News

Researchers have demonstrated that a transplant surgical procedure (called 'needle trauma') triggers a profound immune response and causes the death of most grafted dopamine neurons.

Therapies 189