Broad Institute

MARCH 22, 2024

The new mRNAs, reported in Nature Biotechnology , could potentially be used to treat diseases that require long-lasting treatments that edit genes or replace faulty proteins. “The This feature gives chemists the versatility to extensively engineer the mRNA structure without worrying about changing the information it carries.”

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The Pharma Data

MAY 22, 2023

WHO launches global network to detect and prevent infectious disease threats WHO and partners are launching a global network to help protect people from infectious disease threats through the power of pathogen genomics. New, more transmissible variants of the virus would not have been as quickly identified.

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Broad Institute

DECEMBER 13, 2023

Related news Researchers map brain cell changes in Alzheimer’s disease Courtesy of the Chen and Macosko labs. The researchers also discovered clues about cellular function and the potential roles of brain structures in disease. Courtesy of the Chen and Macosko labs. Our results underscore the need to study them more deeply.”

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Drug Target Review

JANUARY 26, 2024

These ACE2-coated particles could be tested as an anti-viral therapeutic, and as sensors for detecting virus particles. To find a DNA fragment that contained the intact ACE2 gene, complete with its embedded regulatory information, they searched libraries of cloned DNA fragments generated as part of the Human Genome Project.

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The Pharma Data

MARCH 3, 2022

The FDA decision is informed by the results of the Phase 2b proof-of-concept study of RSVpreF (NCT04032093), a global, double-blinded, placebo-controlled study that assessed the safety and immunogenicity of RSVpreF in healthy pregnant women ages 18 through 49 years old, who were vaccinated between 28- and 36-weeks gestation, and their infants.

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The Premier Consulting Blog

JUNE 18, 2023

This has opened new opportunities in pharmaceutical drug development, such as the ability to evaluate large complex databases and to integrate information in useful ways. One exciting application of these technologies is the use of in silico trials in the development of novel therapies for rare diseases.

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Codon

SEPTEMBER 29, 2024

The earliest ones relied on simple linear regression and attempted to correlate genetic variations with observable traits or disease risks — such as drug metabolization rates or cancer susceptibility. Over the decade, entire categories of diseases disappeared. 2024 Statistical models of organisms have existed for decades.

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The Pharma Data

APRIL 14, 2021

The product’s early Marek’s disease onset of immunity from five days of age provides full protection of broilers, layers and breeders against the most virulent Marek’s disease virus strains. Its purpose is to provide poultry producers with cutting-edge technology in terms of Marek’s disease protection.

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Codon

FEBRUARY 13, 2024

doi: 10.2210/rcsb_pdb/goodsell-gallery-048 The Virus that Cures It’s been over 25 years since the science magazine Discover first ran an extraordinary article about how a long-forgotten medical treatment, used in the former Soviet country of Georgia, could save us from the growing threat of untreatable, drug-resistant infections.

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Drug Target Review

JANUARY 15, 2024

CD8+ T cells are a type of lymphocyte that specialises in scanning information presented by HLA Class I. This produces a great advantage in infectious disease, as it becomes difficult for a virus to adapt and spread from person to person, because each person’s HLA array is genetically distinct.

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Drug Target Review

SEPTEMBER 4, 2023

There have been several studies that have reported the ability of infectious disease agents to be drug resistant. Infectious agent includes bacteria, virus, fungi, and parasites, and they are capable of causing disease in a living organism. 7,13 The use of Plants extract is important in drug discovery.

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The Pharma Data

DECEMBER 5, 2020

5, 2020 — A pair of new gene therapies promise a potentially lasting cure for sickle cell disease by subtly altering the genetic information in patients’ bone marrow cells, researchers report. Bluebird’s method “uses a virus to drop an entire gene encoding a new hemoglobin. SATURDAY, Dec.

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Codon

JANUARY 21, 2024

Today, refined versions of these human challenge studies have become standard practice in testing vaccines for vector-borne diseases (e.g., yellow fever, malaria, and dengue), evaluating new drugs or treatments, and studying pathogenesis, the process by which a disease develops. How are disease targets selected for challenge trials?

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The Pharma Data

AUGUST 15, 2021

Food and Drug Administration (FDA) has granted Fast Track designation to VTX-801, Vivet’s clinical-stage gene therapy for the treatment of Wilson Disease – a rare, genetic disorder that reduces the ability of the liver and other tissues to regulate copper levels, causing severe hepatic damage, neurological symptoms, and potentially death.

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The Pharma Data

JANUARY 21, 2021

President Joe Biden has promised to re-energize the nation’s response to COVID-19, but one of his top pandemic advisors says that effort could be hamstrung by both the virus and the failings of the previous administration. Further Support and Information on COVID-19. © 2021 HealthDay. All rights reserved. Posted: January 2021.

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The Pharma Data

JULY 21, 2021

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company focused on the development and commercialization of prophylactic vaccines for infectious diseases with significant unmet medical need, and Pfizer Inc. About Lyme Disease. Juan Carlos Jaramillo M.D., About VLA15.

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DrugBank

JULY 18, 2024

Vaccines have consistently demonstrated their efficacy in protecting people from infectious diseases. This led to the eradication of smallpox and polio – two debilitating diseases that historically caused global epidemics. Let’s take a deeper dive into these challenges.

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Codon

AUGUST 27, 2024

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. Sometimes, though, novel diseases do emerge, and as COVID-19 demonstrated, they can surprise us. This is the third essay of four in our pandemic mini-issue.

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Nvidia Developer: Drug Discovery

OCTOBER 5, 2021

A new study out of the Massachusetts Institute of Technology (MIT) could arm healthcare workers with the information needed to effectively treat COVID-19. A new study out of the Massachusetts Institute of Technology (MIT) could arm healthcare workers with the information needed to effectively treat COVID-19 patients.

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The Pharma Data

NOVEMBER 29, 2021

1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE). Severity of disease : It is not yet clear whether infection with Omicron causes more severe disease compared to infections with other variants, including Delta.

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Drug Target Review

DECEMBER 5, 2024

2 Since then, the FDA has approved four more AAV-based gene therapies—Zolgensma, Hemgenix, Elevidys and Rocktavian—for treating various diseases. 2 Since then, the FDA has approved four more AAV-based gene therapies—Zolgensma, Hemgenix, Elevidys and Rocktavian—for treating various diseases. Signal Transduct Target Ther. 2024;9(1):78.

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The Pharma Data

NOVEMBER 11, 2020

“As an orally bioavailable small molecule with broad antiviral activity, SLV213 could be a valuable treatment to meet today’s urgent need to fight COVID-19 as well other life-threatening infectious diseases, such as Chagas disease, Ebola virus disease, and Nipah virus infection.”.

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The Pharma Data

JUNE 30, 2021

For their remarkable scientific contributions, doctoral student Julia Klaus, Zurich University VetSuisse Faculty, and Dr Yasmin Parr from the MRC-University of Glasgow, Centre for Virus Research, have received the 2021 ABCD Young Scientist Award. To foster young talent development in the feline health research community.

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The Pharma Data

DECEMBER 22, 2020

None of the newborns of the 127 pregnant women, including 64 who had varying levels of illness from the virus, tested positive for the coronavirus. The study also included 63 pregnant women who tested negative for the virus and 11 reproductive-age women who were not pregnant, to provide comparison. ” © 2020 HealthDay.

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Broad Institute

SEPTEMBER 30, 2024

Today, about a third of Broad’s Terra users are from the public health workforce; in the US, 76 state and local public health labs use the platform for preventing and monitoring infectious disease spread in their communities. This was true in the US and all the more in the Global South, where the burden of infectious disease is the highest.

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The Pharma Data

JANUARY 26, 2021

The person is being interviewed for more information about their illness, travel, and contacts, the Associated Press reported. “We know that even as we work hard to defeat COVID-19, the virus continues to evolve as all viruses do,” Minnesota Health Commissioner Jan Malcolm said in a statement. Associated Press Article.

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The Pharma Data

JANUARY 31, 2021

Similar to other enveloped RNA viruses such as HIV, RSV and Influenza, SARS-CoV-2 is also an RNA virus that has a trimeric spike (S) protein on its viral envelope. For more information, please visit our website: www.cloverbiopharma.com. For more information, visit www.dynavax.com. . CHENGDU, China , Feb. About Dynavax.

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The Pharma Data

JANUARY 11, 2021

The COVID-19 vaccines work by teaching the immune system to protect against the virus, experts said. Neither of the two vaccines approved in the United States — made by Pfizer-BioNTech and Moderna — contains the live virus. Centers for Disease Control and Prevention. Further Support and Information on COVID-19.

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The Pharma Data

DECEMBER 16, 2020

Most experts believe the severe acute respiratory syndrome coronavirus 2 virus originated in animals in China, probably bats, the Associated Press reported. Tracking down the animal in which the virus emerged will be key, so the group will take samples of further bat species and other animals that might harbor it. AP News Article.

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The Pharma Data

DECEMBER 16, 2020

Most experts believe the SARS-CoV-2 virus originated in animals in China, probably bats, the Associated Press reported. The objective of the 10-person WHO team is to gather information to better prepare for possible future outbreaks, according to team member Fabian Leendertz, a German biologist who specializes in emerging diseases.

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Advarra

JUNE 13, 2024

The following information includes common elements to consider in site hazard communications and use of this “bundling” approach to simplify things for stakeholders (this is the approach Advarra’s IBC has taken). However, some degree of virulence and risk is acceptable, depending on the disease and subject population being treated.

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Drug Target Review

OCTOBER 25, 2023

These white blood cells destroy diseased cells around the body, but in early pregnancy these natural killer cells in the decidua play a key role in the vast tissue and blood vessel remodelling required for the placenta to properly develop and for the foetus to begin receiving nutrients and oxygen from the parent. “One

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The Pharma Data

FEBRUARY 25, 2021

5 To date, ticks infected with the TBE virus have been identified in more than 35 countries across Europe and Asia. 5 The European Centre for Disease Prevention and Control (ECDC) currently recommends TBE vaccination for people who live in or are traveling to these risk areas. About TicoVac (TBE vaccine, whole virus inactivated).

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The Pharma Data

MARCH 21, 2022

April 6, to discuss considerations for future COVID-19 vaccine booster doses and the process for selecting specific strains of the SARS-CoV-2 virus for COVID-19 vaccines to address current and emerging variants. Centers for Disease Control and Prevention and the National Institutes of Health will participate in the meeting. “As

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Codon

NOVEMBER 8, 2024

Molecular biologists tend to focus on characteristics like metabolism, growth and development, response to stimuli, reproduction, and the ability to process information or evolve. Mitochondria also process information and interact with their environment, much like a human cell. Image by the author.

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The Pharma Data

AUGUST 15, 2021

adults and children against the TBE virus when visiting or living in TBE endemic areas. Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) is expected to discuss recommendations on the safe and appropriate use of TICOVAC. Important Safety Information for TICOVAC.

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The Pharma Data

JANUARY 21, 2021

Mirella Salvatore, an infectious disease expert and assistant professor at Weill Cornell Medicine in New York City. “The spike protein is needed to bind to the cell, to allow the virus to enter,” Salvatore explained. This is a possibility why this virus seems to transmit more easily.” interview this week.

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