The Pharma Data

AUGUST 16, 2020

Eva Larkai, a fourth-year medical student, led the student group demanding change. A major British medical school is leading the drive to eliminate what it calls “inherent racism” in the way doctors are trained in the UK. And he says the problem is one that all UK medical schools and the wider NHS share.

Medical Schools 52

Medical Schools Doctors Government Drug Trials 52

Broad Institute

APRIL 2, 2024

Scientists link certain gut bacteria to lower heart disease risk By Allessandra DiCorato April 2, 2024 Breadcrumb Home Scientists link certain gut bacteria to lower heart disease risk Study finds several species of cholesterol-metabolizing bacteria in people with lower cholesterol levels. Online April 2, 2024. DOI:10.1016/j.cell.2024.03.014.

Disease 145

Disease Medical Schools Hospitals DNA 145

Drug Discovery World

FEBRUARY 15, 2024

Collaboration and partnerships Alys is working with institutions such as Institut Gustave Roussy, UMass Chan Medical School, Icahn School of Medicine at Mount Sinai, Georgia Institute of Technology and Empa, the Swiss Federal Laboratories for Materials Science & Technology.

Medical Schools 130

Medical Schools Pharmaceuticals Laboratories Disease 130

Drug Discovery World

JUNE 26, 2024

Scientists at the University of Bristol have uncovered a new disease driving mechanism which they are aiming to target to help treat the development of atherosclerotic plaques. This unique award will allow us to develop a therapeutic to target this novel non-coding RNA, and validate its use in patients with heart disease.”

Treatment 148

Treatment Research Medical Schools RNA 148

Broad Institute

AUGUST 7, 2024

At the Broad, he directs the Cancer Genome Computational Analysis Group , and he is a professor of pathology at Harvard Medical School and director of bioinformatics at Massachusetts General Hospital. Anna Greka ’s research focuses on fundamental mechanisms of cellular dysfunction in genetic diseases with a focus on membrane proteins.

Medical Schools 90

Medical Schools Hospitals Bioinformatics Vaccine 90

Drug Discovery World

DECEMBER 6, 2023

Gremlin 1 cells present opportunities for cartilage regeneration and their discovery will have relevance to other forms of cartilage injury and disease, which are notoriously challenging to repair and treat.

Medical Schools 265

Medical Schools Clinical Trials Pharmaceuticals Trials 265

Drug Discovery World

SEPTEMBER 3, 2024

Semaglutide has been found to reduce the rates of all-cause death, including as a result of Covid-19, in those who are overweight or have obesity and established cardiovascular disease without diabetes. It wouldn’t surprise me that improving people’s health this way actually slows down the ageing process.”

Medical Schools 148

Medical Schools Trials Disease Hospitals 148

Drug Discovery World

JULY 5, 2024

Amgen has reported positive topline results from its randomised, double-blind, multicentre, placebo-controlled Phase III clinical trial evaluating the efficacy and safety of its treatment for Immunoglobulin G4-related disease (IgG4-RD). ” Amgen is now planning to file for approval in the US following results on the MITIGATE study. .

Treatment 148

Treatment Medical Schools Trials Clinical Trials 148

Drug Target Review

JULY 13, 2023

In this article, we will delve into the world of condensate biology and explore the groundbreaking research projects undertaken to discover the potential they hold for diseases such as amyotrophic lateral sclerosis ( ALS ) and colorectal cancer. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Medical Schools 98

Broad Institute

JANUARY 25, 2024

They found significant associations between the thinning of different retinal layers and increased risk of developing ocular, cardiac, pulmonary, metabolic, and neuropsychiatric diseases and identified genes that are associated with retinal layer thickness. Their findings are published in Science Translational Medicine. “We

Disease 124

Disease Research Medical Schools Science 124

Broad Institute

OCTOBER 23, 2023

By Makenzie Kohler October 23, 2023 People of South Asian ancestry around the world have more than double the risk of developing cardiometabolic diseases like diabetes, heart attack, and stroke compared to other populations.

Disease 145

Disease Research Hospitals DNA 145

biobide

FEBRUARY 2, 2024

Pediatric cancers exhibit differences at the genetic level compared to the same form of adult disease, which may influence the selected treatment. This New Alternative Model (NAM) provides a platform for High-Content Screening through disease modeling through the transplantation of primary patient tumors into immunocompromised lines.

Disease 59

Disease Medical Schools Pharma Companies Clinical Trials 59

Drug Discovery World

OCTOBER 13, 2023

Researchers at Harvard Medical School (HMS) in the US and the University of Oxford have developed a new artificial intelligence (AI) tool named EVEscape that can predict new viral variants before they emerge. According to the European Centre for Prevention and Disease Control, the current variants of interest are Omicron variants BA.2.75,

Vaccine 265

Vaccine Virus Medical Schools Immune Response 265

Drug Discovery World

FEBRUARY 6, 2024

Catherine Brownstein is an Assistant Professor in Pediatrics at Harvard Medical School and the Assistant Director of the Molecular Genetics Core Facility at Boston Children’s Hospital. And, once a potential target has been identified, genomics can be used to validate its role in the disease process.

Medical Schools 148

Medical Schools Clinical Trials Assay Development Hospitals 148

Drug Discovery World

AUGUST 25, 2023

A new study at UTHealth Houston in the US has found that several routine vaccinations are linked to a significant reduced risk of Alzheimer’s disease (AD). Paul Schulz, the Rick McCord Professor in Neurology with McGovern Medical School at UTHealth Houston, was senior author of the study.

Vaccine 130

Vaccine Medical Schools Immune Response Disease 130

Broad Institute

JULY 6, 2023

The accuracy of these scores has improved for some diseases and groups of people, but they continue to fall short for those of non-European ancestry, mainly because the genetic datasets used to calculate these scores have largely come from people of European ancestry.

Disease 97

Disease DNA Hospitals Medical Schools 97

Drug Discovery World

AUGUST 2, 2023

These models would create another avenue to predict disease and study treatment on a personalised level for conditions that often vary greatly from person to person.”

Research 130

Research Medical Schools Engineering Disease 130

Drug Discovery World

DECEMBER 5, 2022

Scientists have unlocked key insights into virus evolution, revealing new information that could help develop treatments for a wide variety of genetic diseases. . It was led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR) and University of Massachusetts Chan Medical School. .

Virus 130

Virus Therapies Treatment Medical Schools 130

Drug Discovery World

JANUARY 5, 2023

CANbridge Pharmaceuticals has exercised its option to secure the exclusive global rights to develop, manufacture and commercialise a novel gene therapy to treat spinal muscular atrophy (SMA) from UMass Chan Medical School. . It also exhibited much less liver toxicity when administered intravenously. . “The

Therapies 130

Therapies Medical Schools Clinical Development Pharmaceuticals 130

Drug Discovery World

JULY 21, 2022

Two doses of Covid-19 vaccines were sufficient in providing protection against severe cases of the infectious disease, according to new research. . Dr Elsie Horne, Senior Research Associate in Medical Statistics and Health Data Science in?Bristol Bristol Medical School: Population Health Sciences (PHS)?and

Vaccine 130

Vaccine Medical Schools Hospitals Science 130

Drug Discovery World

JULY 3, 2023

Janssen has announced positive results from the proof-of-concept Phase II UNITY trial for the treatment of pregnant individuals at high risk of early-onset severe (EOS) haemolytic disease of the foetus and newborn (HDFN).

Trials 130

Trials Medical Schools Clinical Development Treatment 130

Broad Institute

AUGUST 8, 2024

at Harvard Medical School, where he conducted research with Pardis Sabeti on evolution of human genetic resistance to infectious disease. Tabrizi earned his M.D.

Medical Schools 52

Medical Schools Hospitals DNA Engineering 52

The Pharma Data

JANUARY 25, 2021

25, 2021 — Recommendations are presented for the diagnosis and management of von Willebrand disease (VWD) in two clinical guidelines issued by the American Society of Hematology, International Society on Thrombosis and Haemostasis, National Hemophilia Foundation, and World Federation of Hemophilia and published online Jan. MONDAY, Jan.

Disease 52

Disease Medical Schools Laboratories Therapies 52

Drug Discovery World

FEBRUARY 2, 2023

The Food and Drug Administration (FDA) has approved Orserdu (elacestrant) for the treatment of postmenopausal women or adult men, with ER+, HER2-, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy. Stemline Therapeutics, a wholly-owned subsidiary of the Menarini Group, will (..)

FDA Approval 130

FDA Approval Therapies FDA Medical Schools 130

Drug Discovery World

MARCH 15, 2023

First new treatment in 45 years Lead researcher Dr Darrell Green, from UEA’s Norwich Medical School, was inspired to study childhood bone cancer after his best friend died from the disease as a teenager. CADD522 is a small molecule which blocks the RUNX2 protein from having an effect.

Small Molecule 130

Small Molecule Medical Schools Drugs Clinical Trials 130

Drug Target Review

APRIL 26, 2023

Scientists from the Massachusetts Institute of Technology (MIT) and the University of Massachusetts Medical School (UMass), US, have collaborated to create a novel type of nanoparticle that can deliver messenger RNA that encodes for beneficial proteins to the lungs.

RNA 98

RNA Medical Schools Engineering DNA 98

Broad Institute

JUNE 18, 2024

The test, developed by a team from the Broad Institute of MIT and Harvard and Princeton University, and supported by the US Centers for Disease Control and Prevention, uses CRISPR to distinguish between the two main types of seasonal flu, influenza A and B, as well as seasonal flu subtypes H1N1 and H3N2. The Journal of Molecular Diagnostics.

Virus 144

Virus RNA Medical Schools Laboratories 144

Drug Discovery World

NOVEMBER 23, 2023

Department of Defense (D o D) a nd over 50 strategic relationships with medical schools, universities, and hospitals worldwide, it is noteworthy that a valiant attempt must always be at the forefront of embracing diversity, not only from an ethnic perspective, but also geographically.

Drugs 148

Drugs Medical Schools Trials Disease 148

Broad Institute

JULY 25, 2024

OurHealth’s medical director, Dr.

Medical Schools 52

Medical Schools Hospitals Disease 52

Broad Institute

MARCH 8, 2024

“Type 2 diabetes is a disease of elevated blood sugar impacting approximately one in 10 people in the United States that can cause devastating health complications and is usually not cured. Udler and her colleagues assessed genetic findings from more than 1.4 Adapted from an MGH press release. Paper cited: Smith K, Deutsch AJ, McGrail C.,

Medical Schools 127

Medical Schools Hospitals Disease Therapies 127

Broad Institute

OCTOBER 16, 2023

She helps lead a team that processes a variety of sample types to support research at the institute focused on a wide range of diseases. She previously served as a flow cytometry specialist at Harvard University and as a research technician at Harvard Medical School. Rogers earned a B.S.

Medical Schools 52

Medical Schools Science Disease Research 52

PLOS: DNA Science

JULY 27, 2023

That information led, thanks to vaccine shelved from the first SARS circa 2003, to the rapid development and deployment of mRNA vaccines against the new infectious disease. Harvard Medical School researchers recently described an “AI tool” that “Decodes Brain Cancer’s Genome During Surgery,” in the journal Med.

Disease 68

Disease DNA Virus RNA 68

Broad Institute

AUGUST 19, 2024

This study is an important example of how understanding core metabolic requirements and functions of key bacteria can lead directly to new therapies that allow us to modify the microbiome for improved health,” said co-senior author Seth Bloom, an infectious diseases instructor at the Massachusetts General Hospital.

Hospitals 121

Hospitals Medical Schools Treatment Science 121

Drug Discovery World

APRIL 16, 2023

Currently, surgery is not offered to many patients with potentially resectable disease if rapid recurrence is expected based on tumour burden or the presence of vascular invasion,” he said. The availability of an efficacious adjuvant therapy may lead to a reassessment of which patients may benefit from surgical resection.”

Therapies 130

Therapies Medical Schools Trials Treatment 130

The Pharma Data

JUNE 2, 2022

Novartis today announced a partnership with the American Society of Hematology (ASH) to provide six additional African nations with technology that is already being used in Ghana to document and share the diagnosis of babies with sickle cell disease. About Sickle Cell Disease.

Disease 52

Disease Medical Schools Treatment Therapies 52

Drug Discovery World

NOVEMBER 27, 2023

As the significance of large molecules continues to broaden across diverse modalities, emphasis on bispecific and multispecific antibodies to treat various disorders such as rheumatologic diseases, cancer, diabetes, anaemia, and infectious diseases becomes paramount.

Production 148

Production Engineering Molecular Biology Drug Development 148

The Pharma Data

DECEMBER 3, 2020

New Tau Protein is Abnormal in Very Early Alzheimer’s Disease. Investigators with the University of Gothenburg identified new forms of tau protein that become abnormal in the very early stages of Alzheimer’s disease, even before the development of cognitive problems. Kidney Disease Leading Risk Factor for COVID-related Hospitalization.

Disease 52

Disease Research Virus Hospitals 52